Top articles since 2007

Rank Title Journal Year PubWeight™‹?›
1 A short history of SHELX. Acta Crystallogr A 2007 7339.18
2 Structure validation in chemical crystallography. Acta Crystallogr D Biol Crystallogr 2009 1216.15
3 Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol 2009 235.12
4 The Sequence Alignment/Map format and SAMtools. Bioinformatics 2009 232.39
5 MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol Biol Evol 2011 220.97
6 PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 2007 209.92
7 Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics 2009 190.94
8 Global cancer statistics. CA Cancer J Clin 2011 185.92
9 The RAST Server: rapid annotations using subsystems technology. BMC Genomics 2008 175.18
10 MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. Mol Biol Evol 2007 168.76
11 Crystal structure refinement with SHELXL. Acta Crystallogr C Struct Chem 2015 158.65
12 Mapping short DNA sequencing reads and calling variants using mapping quality scores. Genome Res 2008 157.44
13 Velvet: algorithms for de novo short read assembly using de Bruijn graphs. Genome Res 2008 151.16
14 Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007 144.95
15 Hallmarks of cancer: the next generation. Cell 2011 140.01
16 Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 2009 137.99
17 Mapping and quantifying mammalian transcriptomes by RNA-Seq. Nat Methods 2008 126.81
18 Clustal W and Clustal X version 2.0. Bioinformatics 2007 126.47
19 A map of human genome variation from population-scale sequencing. Nature 2010 121.13
20 MEGA6: Molecular Evolutionary Genetics Analysis version 6.0. Mol Biol Evol 2013 112.81
21 PHENIX: a comprehensive Python-based system for macromolecular structure solution. Acta Crystallogr D Biol Crystallogr 2010 108.52
22 Phaser crystallographic software. J Appl Crystallogr 2007 108.34
23 Cancer statistics, 2010. CA Cancer J Clin 2010 103.28
24 Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007 101.42
25 The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data. Genome Res 2010 97.51
26 MicroRNAs: target recognition and regulatory functions. Cell 2009 92.17
27 Accurate whole human genome sequencing using reversible terminator chemistry. Nature 2008 90.20
28 Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 2010 90.16
29 Features and development of Coot. Acta Crystallogr D Biol Crystallogr 2010 89.46
30 Cancer statistics, 2012. CA Cancer J Clin 2012 87.38
31 Cancer statistics, 2008. CA Cancer J Clin 2008 86.74
32 RNAmmer: consistent and rapid annotation of ribosomal RNA genes. Nucleic Acids Res 2007 85.81
33 High-resolution profiling of histone methylations in the human genome. Cell 2007 85.74
34 A second generation human haplotype map of over 3.1 million SNPs. Nature 2007 85.39
35 QIIME allows analysis of high-throughput community sequencing data. Nat Methods 2010 85.34
36 Cancer statistics, 2013. CA Cancer J Clin 2013 84.72
37 Determination of absolute structure using Bayesian statistics on Bijvoet differences. J Appl Crystallogr 2008 84.57
38 NIH Image to ImageJ: 25 years of image analysis. Nat Methods 2012 84.41
39 Fast gapped-read alignment with Bowtie 2. Nat Methods 2012 83.79
40 Cancer statistics, 2009. CA Cancer J Clin 2009 83.57
41 TopHat: discovering splice junctions with RNA-Seq. Bioinformatics 2009 81.13
42 A method and server for predicting damaging missense mutations. Nat Methods 2010 78.53
43 New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur J Cancer 2009 77.71
44 Introducing mothur: open-source, platform-independent, community-supported software for describing and comparing microbial communities. Appl Environ Microbiol 2009 77.55
45 Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 2008 75.40
46 Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat Biotechnol 2010 75.21
47 Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 2007 75.09
48 BEAST: Bayesian evolutionary analysis by sampling trees. BMC Evol Biol 2007 74.13
49 Cancer statistics, 2014. CA Cancer J Clin 2014 72.81
50 Induced pluripotent stem cell lines derived from human somatic cells. Science 2007 71.50
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