| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Structure validation in chemical crystallography.
|
Acta Crystallogr D Biol Crystallogr
|
2009
|
1216.15
|
|
2
|
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome.
|
Genome Biol
|
2009
|
235.12
|
|
3
|
The Sequence Alignment/Map format and SAMtools.
|
Bioinformatics
|
2009
|
232.39
|
|
4
|
MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods.
|
Mol Biol Evol
|
2011
|
220.97
|
|
5
|
Fast and accurate short read alignment with Burrows-Wheeler transform.
|
Bioinformatics
|
2009
|
190.94
|
|
6
|
Global cancer statistics.
|
CA Cancer J Clin
|
2011
|
185.92
|
|
7
|
Crystal structure refinement with SHELXL.
|
Acta Crystallogr C Struct Chem
|
2015
|
158.65
|
|
8
|
Hallmarks of cancer: the next generation.
|
Cell
|
2011
|
140.01
|
|
9
|
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources.
|
Nat Protoc
|
2009
|
137.99
|
|
10
|
A map of human genome variation from population-scale sequencing.
|
Nature
|
2010
|
121.13
|
|
11
|
MEGA6: Molecular Evolutionary Genetics Analysis version 6.0.
|
Mol Biol Evol
|
2013
|
112.81
|
|
12
|
PHENIX: a comprehensive Python-based system for macromolecular structure solution.
|
Acta Crystallogr D Biol Crystallogr
|
2010
|
108.52
|
|
13
|
Cancer statistics, 2010.
|
CA Cancer J Clin
|
2010
|
103.28
|
|
14
|
The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data.
|
Genome Res
|
2010
|
97.51
|
|
15
|
MicroRNAs: target recognition and regulatory functions.
|
Cell
|
2009
|
92.17
|
|
16
|
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008.
|
Int J Cancer
|
2010
|
90.16
|
|
17
|
Features and development of Coot.
|
Acta Crystallogr D Biol Crystallogr
|
2010
|
89.46
|
|
18
|
Cancer statistics, 2012.
|
CA Cancer J Clin
|
2012
|
87.38
|
|
19
|
QIIME allows analysis of high-throughput community sequencing data.
|
Nat Methods
|
2010
|
85.34
|
|
20
|
Cancer statistics, 2013.
|
CA Cancer J Clin
|
2013
|
84.72
|
|
21
|
NIH Image to ImageJ: 25 years of image analysis.
|
Nat Methods
|
2012
|
84.41
|
|
22
|
Fast gapped-read alignment with Bowtie 2.
|
Nat Methods
|
2012
|
83.79
|
|
23
|
Cancer statistics, 2009.
|
CA Cancer J Clin
|
2009
|
83.57
|
|
24
|
TopHat: discovering splice junctions with RNA-Seq.
|
Bioinformatics
|
2009
|
81.13
|
|
25
|
A method and server for predicting damaging missense mutations.
|
Nat Methods
|
2010
|
78.53
|
|
26
|
New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1).
|
Eur J Cancer
|
2009
|
77.71
|
|
27
|
Introducing mothur: open-source, platform-independent, community-supported software for describing and comparing microbial communities.
|
Appl Environ Microbiol
|
2009
|
77.55
|
|
28
|
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation.
|
Nat Biotechnol
|
2010
|
75.21
|
|
29
|
Cancer statistics, 2014.
|
CA Cancer J Clin
|
2014
|
72.81
|
|
30
|
A new equation to estimate glomerular filtration rate.
|
Ann Intern Med
|
2009
|
71.41
|
|
31
|
Prevention of HIV-1 infection with early antiretroviral therapy.
|
N Engl J Med
|
2011
|
69.36
|
|
32
|
Finding the missing heritability of complex diseases.
|
Nature
|
2009
|
67.95
|
|
33
|
Overview of the CCP4 suite and current developments.
|
Acta Crystallogr D Biol Crystallogr
|
2011
|
67.55
|
|
34
|
XDS.
|
Acta Crystallogr D Biol Crystallogr
|
2010
|
67.46
|
|
35
|
Improved survival with ipilimumab in patients with metastatic melanoma.
|
N Engl J Med
|
2010
|
67.34
|
|
36
|
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data.
|
Bioinformatics
|
2009
|
67.17
|
|
37
|
Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios.
|
Transl Androl Urol
|
2016
|
66.58
|
|
38
|
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement.
|
PLoS Med
|
2009
|
65.36
|
|
39
|
GenAlEx 6.5: genetic analysis in Excel. Population genetic software for teaching and research--an update.
|
Bioinformatics
|
2012
|
65.14
|
|
40
|
An integrated encyclopedia of DNA elements in the human genome.
|
Nature
|
2012
|
64.73
|
|
41
|
Differential expression analysis for sequence count data.
|
Genome Biol
|
2010
|
64.56
|
|
42
|
SPAdes: a new genome assembly algorithm and its applications to single-cell sequencing.
|
J Comput Biol
|
2012
|
62.36
|
|
43
|
An integrated map of genetic variation from 1,092 human genomes.
|
Nature
|
2012
|
59.82
|
|
44
|
A framework for variation discovery and genotyping using next-generation DNA sequencing data.
|
Nat Genet
|
2011
|
59.36
|
|
45
|
RNA-Seq: a revolutionary tool for transcriptomics.
|
Nat Rev Genet
|
2009
|
58.77
|
|
46
|
Cancer statistics, 2015.
|
CA Cancer J Clin
|
2015
|
57.51
|
|
47
|
Fiji: an open-source platform for biological-image analysis.
|
Nat Methods
|
2012
|
56.92
|
|
48
|
Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010.
|
Lancet
|
2012
|
56.72
|
|
49
|
Multiplex genome engineering using CRISPR/Cas systems.
|
Science
|
2013
|
55.53
|
|
50
|
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits.
|
Proc Natl Acad Sci U S A
|
2009
|
54.68
|