Effect of DHEA on Skin Aging in Postmenopausal Women

Clinical Trial ID NCT00248989

PubWeight™ 0.00‹?›

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 The use of estrogens and progestins and the risk of breast cancer in postmenopausal women. N Engl J Med 1995 11.08
2 Differential changes in bone mineral density of the appendicular and axial skeleton with aging: relationship to spinal osteoporosis. J Clin Invest 1981 3.60
3 Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood. J Clin Endocrinol Metab 1984 3.07
4 Source of estrogen production in postmenopausal women. J Clin Endocrinol Metab 1973 2.91
5 A review of the prolonged use of estrogens and androgens in postmenopausal and senile osteoporosis. AMA Arch Intern Med 1957 2.29
6 Marked decline in serum concentrations of adrenal C19 sex steroid precursors and conjugated androgen metabolites during aging. J Clin Endocrinol Metab 1997 1.96
7 Skeletal effects of oral oestrogen compared with subcutaneous oestrogen and testosterone in postmenopausal women. BMJ 1988 1.89
8 On aging bone loss. Clin Orthop Relat Res 1982 1.86
9 Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age. J Clin Endocrinol Metab 1994 1.79
10 The key role of 17 beta-hydroxysteroid dehydrogenases in sex steroid biology. Steroids 1997 1.76
11 Changes in serum concentrations of conjugated and unconjugated steroids in 40- to 80-year-old men. J Clin Endocrinol Metab 1994 1.66
12 Intracrinology. Mol Cell Endocrinol 1991 1.61
13 Endocrine and intracrine sources of androgens in women: inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone. Endocr Rev 2003 1.60
14 Dehydroepiandrosterone (DHEA), DHEA sulfate, and aging: contribution of the DHEAge Study to a sociobiomedical issue. Proc Natl Acad Sci U S A 2000 1.51
15 Testosterone enhances estradiol's effects on postmenopausal bone density and sexuality. Maturitas 1995 1.37
16 Stanozolol in postmenopausal osteoporosis: therapeutic efficacy and possible mechanisms of action. Metabolism 1983 1.32
17 Clinical experience of drug treatments for mastalgia. Lancet 1985 1.26
18 The management of persistent menopausal symptoms with oestradiol-testosterone implants: clinical, lipid and hormonal results. Maturitas 1984 1.21
19 Modulation of growth, differentiation and carcinogenesis by dehydroepiandrosterone. Adv Enzyme Regul 1987 1.18
20 Dehydroepiandrosterone enhances IL2 production and cytotoxic effector function of human T cells. Clin Immunol Immunopathol 1991 1.17
21 Early menopausal changes in bone mass and sex steroids. J Clin Endocrinol Metab 1985 1.16
22 Unique features of the basal cells of human prostate epithelium. Microsc Res Tech 2000 1.16
23 Dehydroepiandrosterone reduces serum low density lipoprotein levels and body fat but does not alter insulin sensitivity in normal men. J Clin Endocrinol Metab 1988 1.14
24 Localization of type 5 17beta-hydroxysteroid dehydrogenase, 3beta-hydroxysteroid dehydrogenase, and androgen receptor in the human prostate by in situ hybridization and immunocytochemistry. Endocrinology 1999 1.14
25 Differential symptom response to parenteral estrogen and/or androgen administration in the surgical menopause. Am J Obstet Gynecol 1985 1.11
26 Sex steroids and bone density in premenopausal and perimenopausal women. J Clin Endocrinol Metab 1989 1.11
27 Physiological changes in dehydroepiandrosterone are not reflected by serum levels of active androgens and estrogens but of their metabolites: intracrinology. J Clin Endocrinol Metab 1997 1.10
28 DHEA and peripheral androgen and estrogen formation: intracinology. Ann N Y Acad Sci 1995 1.09
29 Therapeutic effects of dehydroepiandrosterone (DHEA) in diabetic mice. Diabetes 1982 1.09
30 Dehydroepiandrosterone and androsterone levels in human plasma: effect of age and sex; day-to-day and diurnal variations. J Clin Endocrinol Metab 1957 1.09
31 The role of androgen in the maintenance of sexual functioning in oophorectomized women. Psychosom Med 1987 1.05
32 Oral dehydroepiandrosterone in physiologic doses modulates immune function in postmenopausal women. Am J Obstet Gynecol 1993 1.03
33 Twenty-four-hour mean plasma testosterone concentration declines with age in normal premenopausal women. J Clin Endocrinol Metab 1995 1.02
34 Effect of 12-month dehydroepiandrosterone replacement therapy on bone, vagina, and endometrium in postmenopausal women. J Clin Endocrinol Metab 1997 1.02
35 Reduced testosterone and adrenal C19 steroid levels in obese men. Metabolism 1995 1.01
36 Affective changes with estrogen and androgen replacement therapy in surgically menopausal women. J Affect Disord 1988 0.96
37 Clinical, biochemical, radiographic, epidemiologic, and economic features of osteoporosis. Orthop Clin North Am 1981 0.95
38 Vaginal atrophy in the postmenopausal woman. The importance of sexual activity and hormones. JAMA 1983 0.94
39 High-affinity androgen binding and androgenic regulation of alpha 1(I)-procollagen and transforming growth factor-beta steady state messenger ribonucleic acid levels in human osteoblast-like osteosarcoma cells. Endocrinology 1991 0.94
40 Metabolic effects of 12-month percutaneous dehydroepiandrosterone replacement therapy in postmenopausal women. J Endocrinol 1996 0.89
41 Divergent correlations of circulating dehydroepiandrosterone sulfate and testosterone with insulin levels and insulin receptor binding. J Clin Endocrinol Metab 1988 0.87
42 Role of 17 beta-hydroxysteroid dehydrogenases in sex steroid formation in peripheral intracrine tissues. Trends Endocrinol Metab 2000 0.84
43 Prevention by dehydroepiandrosterone of the development of mammary carcinoma induced by 7,12-dimethylbenz(a)anthracene (DMBA) in the rat. Breast Cancer Res Treat 1994 0.83
44 RU486, a progestin and glucocorticoid antagonist, inhibits the growth of breast cancer cells via the progesterone receptor. J Clin Endocrinol Metab 1985 0.82
45 Effectiveness of dehydroepiandrosterone in reduction of cryptosporidial activity in immunosuppressed rats. Antimicrob Agents Chemother 1992 0.82
46 Inhibition of tumor development by dehydroepiandrosterone and related steroids. Toxicol Pathol 1986 0.82
47 Dehydroepiandrosterone (DHEA) and synthetic DHEA analogs are modest inhibitors of HIV-1 IIIB replication. AIDS Res Hum Retroviruses 1992 0.80
48 Effects of nandrolone decanoate and antiresorptive therapy on vertebral density in osteoporotic postmenopausal women. Arch Intern Med 1989 0.80
49 Androgenic activity of dehydroepiandrosterone and androstenedione in the rat ventral prostate. Endocrinology 1988 0.79
50 Radioimmunoassay of 17beta-hydroxy-5alpha-androstan-3-one, 4-androstene-3,17-dione, dehydroepiandrosterone, 17-hydroxyprogesterone and progesterone and its application to the human male plasma. J Steroid Biochem 1976 0.78
51 Influence of testosterone and dihydrotestosterone on bone-matrix induced endochondral bone formation. Calcif Tissue Int 1989 0.78
52 Effects of parenteral administration of estrogen and androgen on plasma hormone levels and hot flushes in the surgical menopause. Am J Obstet Gynecol 1984 0.78
53 Obesity in the dog: role of the adrenal steroid dehydroepiandrosterone (DHEA). J Nutr 1991 0.77
54 Adrenocortical function in old age: response to acute adrenocorticotropin stimulation. J Clin Endocrinol Metab 1982 0.75
55 Direct action of androgen on hot flushes in the human male. Maturitas 1984 0.75
56 Exclusive androgenic effect of dehydroepiandrosterone in sebaceous glands of rat skin. J Endocrinol 2000 0.75
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