Lifestyle Intervention in a General Population for Prevention of Ischaemic Heart Disease

Clinical Trial ID NCT00289237

PubWeight™ 67.90‹?›

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Richness of human gut microbiome correlates with metabolic markers. Nature 2013 6.93
2 Effect of screening and lifestyle counselling on incidence of ischaemic heart disease in general population: Inter99 randomised trial. BMJ 2014 5.55
3 Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia. Nat Genet 2009 5.43
4 A randomized non-pharmacological intervention study for prevention of ischaemic heart disease: baseline results Inter99. Eur J Cardiovasc Prev Rehabil 2003 4.25
5 Prevalences of diabetes and impaired glucose regulation in a Danish population: the Inter99 study. Diabetes Care 2003 2.96
6 A Danish diabetes risk score for targeted screening: the Inter99 study. Diabetes Care 2004 2.65
7 Dietary glycemic index, glycemic load, fiber, simple sugars, and insulin resistance: the Inter99 study. Diabetes Care 2005 2.00
8 Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes. Diabetes 2008 1.55
9 Natural selection affects multiple aspects of genetic variation at putatively neutral sites across the human genome. PLoS Genet 2011 1.54
10 Habitual sleep duration is associated with BMI and macronutrient intake and may be modified by CLOCK genetic variants. Am J Clin Nutr 2014 1.53
11 Natural history of insulin sensitivity and insulin secretion in the progression from normal glucose tolerance to impaired fasting glycemia and impaired glucose tolerance: the Inter99 study. Diabetes Care 2008 1.50
12 Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes. Am J Hum Genet 2013 1.43
13 Progression to impaired glucose regulation and diabetes in the population-based Inter99 study. Diabetes Care 2008 1.30
14 Combined analyses of 20 common obesity susceptibility variants. Diabetes 2010 1.27
15 G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans. Diabetes 2009 1.27
16 The functional Thr130Ile and Val255Met polymorphisms of the hepatocyte nuclear factor-4alpha (HNF4A): gene associations with type 2 diabetes or altered beta-cell function among Danes. J Clin Endocrinol Metab 2005 1.22
17 Non-replication of genome-wide based associations between common variants in INSIG2 and PFKP and obesity in studies of 18,014 Danes. PLoS One 2008 1.17
18 The common T60N polymorphism of the lymphotoxin-alpha gene is associated with type 2 diabetes and other phenotypes of the metabolic syndrome. Diabetologia 2005 1.17
19 Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian Danes. Diabetologia 2005 1.16
20 Sex differences in glucose levels: a consequence of physiology or methodological convenience? The Inter99 study. Diabetologia 2010 1.16
21 Obesity and central fat pattern among Greenland Inuit and a general population of Denmark (Inter99): relationship to metabolic risk factors. Int J Obes Relat Metab Disord 2003 1.15
22 Low birthweight and premature birth are both associated with type 2 diabetes in a random sample of middle-aged Danes. Diabetologia 2010 1.11
23 Smoking cessation intervention in a large randomised population-based study. The Inter99 study. Prev Med 2005 1.10
24 Small, hard macular drusen and peripheral drusen: associations with AMD genotypes in the Inter99 Eye Study. Invest Ophthalmol Vis Sci 2009 1.10
25 It is possible to help smokers in early motivational stages to quit. The Inter99 study. Prev Med 2005 1.10
26 Sleep disturbances are related to decreased transmission of blue light to the retina caused by lens yellowing. Sleep 2011 1.07
27 Analysis of separate and combined effects of common variation in KCNJ11 and PPARG on risk of type 2 diabetes. J Clin Endocrinol Metab 2005 1.05
28 Variants near MC4R are associated with obesity and influence obesity-related quantitative traits in a population of middle-aged people: studies of 14,940 Danes. Diabetes 2008 1.05
29 Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets. PLoS Genet 2013 1.04
30 Studies of metabolic phenotypic correlates of 15 obesity associated gene variants. PLoS One 2011 1.03
31 Identification of KCNJ15 as a susceptibility gene in Asian patients with type 2 diabetes mellitus. Am J Hum Genet 2010 1.01
32 Motivational counseling to reduce sitting time: a community-based randomized controlled trial in adults. Am J Prev Med 2014 0.96
33 Studies of relationships between variation of the human G protein-coupled receptor 40 Gene and Type 2 diabetes and insulin release. Diabet Med 2005 0.95
34 The effect of PCSK1 variants on waist, waist-hip ratio and glucose metabolism is modified by sex and glucose tolerance status. PLoS One 2011 0.95
35 Effect of lifestyle factors on plasma total homocysteine concentrations in relation to MTHFR(C677T) genotype. Inter99 (7). Eur J Clin Nutr 2004 0.94
36 Variation in the peroxisome proliferator-activated receptor delta gene in relation to common metabolic traits in 7,495 middle-aged white people. Diabetologia 2007 0.94
37 PGC-1alpha Gly482Ser polymorphism associates with hypertension among Danish whites. Hypertension 2005 0.93
38 Investigating the causal effect of vitamin D on serum adiponectin using a Mendelian randomization approach. Eur J Clin Nutr 2013 0.93
39 Studies of the association of Arg72Pro of tumor suppressor protein p53 with type 2 diabetes in a combined analysis of 55,521 Europeans. PLoS One 2011 0.92
40 Implications of central obesity-related variants in LYPLAL1, NRXN3, MSRA, and TFAP2B on quantitative metabolic traits in adult Danes. PLoS One 2011 0.92
41 Do gene variants influencing adult adiposity affect birth weight? A population-based study of 24 loci in 4,744 Danish individuals. PLoS One 2010 0.92
42 Variation of the McKusick-Kaufman gene and studies of relationships with common forms of obesity. J Clin Endocrinol Metab 2004 0.92
43 Variation near the hepatocyte nuclear factor (HNF)-4alpha gene associates with type 2 diabetes in the Danish population. Diabetologia 2005 0.91
44 Evidence of an association between genetic variation of the coactivator PGC-1beta and obesity. J Med Genet 2005 0.91
45 Large-scale studies of the HphI insulin gene variable-number-of-tandem-repeats polymorphism in relation to Type 2 diabetes mellitus and insulin release. Diabetologia 2004 0.90
46 What is the contribution of two genetic variants regulating VEGF levels to type 2 diabetes risk and to microvascular complications? PLoS One 2013 0.90
47 Atopy and development of cancer: a population-based prospective study. J Allergy Clin Immunol Pract 2014 0.89
48 Genetic risk score of 46 type 2 diabetes risk variants associates with changes in plasma glucose and estimates of pancreatic β-cell function over 5 years of follow-up. Diabetes 2013 0.88
49 A statistical approach based on substitution of macronutrients provides additional information to models analyzing single dietary factors in relation to type 2 diabetes in danish adults: the Inter99 study. J Nutr 2005 0.88
50 Acceptance of the smoking cessation intervention in a large population-based study: the Inter99 study. Scand J Public Health 2005 0.88
51 Visual acuity and refractive errors in a suburban Danish population: Inter99 Eye Study. Acta Ophthalmol Scand 2004 0.87
52 Contribution of thermolabile methylenetetrahydrofolate reductase variant to total plasma homocysteine levels in healthy men and women. Inter99 (2). Genet Epidemiol 2003 0.87
53 Comparison of accuracy of diabetes risk score and components of the metabolic syndrome in assessing risk of incident type 2 diabetes in Inter99 cohort. PLoS One 2011 0.87
54 Neighborhood deprivation is strongly associated with participation in a population-based health check. PLoS One 2015 0.86
55 Precursors of age-related macular degeneration: associations with physical activity, obesity, and serum lipids in the inter99 eye study. Invest Ophthalmol Vis Sci 2013 0.85
56 Evidence of an association between the Arg72 allele of the peptide YY and increased risk of type 2 diabetes. Diabetes 2005 0.84
57 The birth weight lowering C-allele of rs900400 near LEKR1 and CCNL1 associates with elevated insulin release following an oral glucose challenge. PLoS One 2011 0.83
58 Can a screening programme for diabetes be applied to another population? Diabet Med 2005 0.83
59 Targeted screening for undiagnosed diabetes reduces the number of diagnostic tests. Inter99(8). Diabet Med 2004 0.83
60 Differential relationship between physical activity and progression to diabetes by glucose tolerance status: the Inter99 Study. Diabetologia 2009 0.83
61 Smoking reduction intervention in a large population-based study. The Inter99 study. Prev Med 2005 0.82
62 The minor C-allele of rs2014355 in ACADS is associated with reduced insulin release following an oral glucose load. BMC Med Genet 2011 0.82
63 Evidence for an association between the Leu162Val polymorphism of the PPARalpha gene and decreased fasting serum triglyceride levels in glucose tolerant subjects. Pharmacogenetics 2003 0.82
64 The PNPLA3 rs738409 G-allele associates with reduced fasting serum triglyceride and serum cholesterol in Danes with impaired glucose regulation. PLoS One 2012 0.81
65 Gene-Environment Interactions of Circadian-Related Genes for Cardiometabolic Traits. Diabetes Care 2015 0.81
66 Interaction between genetic predisposition to obesity and dietary calcium in relation to subsequent change in body weight and waist circumference. Am J Clin Nutr 2014 0.81
67 Risk factors associated with serum levels of the inflammatory biomarker soluble urokinase plasminogen activator receptor in a general population. Biomark Insights 2014 0.81
68 Studies of relationships between the GLUT10 Ala206Thr polymorphism and impaired insulin secretion. Diabet Med 2005 0.81
69 Large-scale studies of the functional K variant of the butyrylcholinesterase gene in relation to Type 2 diabetes and insulin secretion. Diabetologia 2004 0.80
70 Lack of association between PKLR rs3020781 and NOS1AP rs7538490 and type 2 diabetes, overweight, obesity and related metabolic phenotypes in a Danish large-scale study: case-control studies and analyses of quantitative traits. BMC Med Genet 2008 0.80
71 Studies of CTNNBL1 and FDFT1 variants and measures of obesity: analyses of quantitative traits and case-control studies in 18,014 Danes. BMC Med Genet 2009 0.80
72 Association studies of novel obesity-related gene variants with quantitative metabolic phenotypes in a population-based sample of 6,039 Danish individuals. Diabetologia 2011 0.80
73 No consistent effect of ADRB2 haplotypes on obesity, hypertension and quantitative traits of body fatness and blood pressure among 6,514 adult Danes. PLoS One 2009 0.80
74 Studies of a genetic variant in HK1 in relation to quantitative metabolic traits and to the prevalence of type 2 diabetes. BMC Med Genet 2011 0.80
75 A genetic risk score of 45 coronary artery disease risk variants associates with increased risk of myocardial infarction in 6041 Danish individuals. Atherosclerosis 2015 0.78
76 Effects of general health checks differ under two different analyses perspectives-the Inter99 randomized study. J Clin Epidemiol 2015 0.77
77 Neighborhood social capital is associated with participation in health checks of a general population: a multilevel analysis of a population-based lifestyle intervention- the Inter99 study. BMC Public Health 2015 0.77
78 Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity. PLoS One 2010 0.77
79 Serum 25-Hydroxyvitamin D Status and Longitudinal Changes in Weight and Waist Circumference: Influence of Genetic Predisposition to Adiposity. PLoS One 2016 0.77
80 The relationship between changes in health behaviour and initiation of lipid-lowering and antihypertensive medications in individuals at high risk of ischaemic heart disease. BMC Public Health 2012 0.76
81 Studies of association of AGPAT6 variants with type 2 diabetes and related metabolic phenotypes in 12,068 Danes. BMC Med Genet 2013 0.76
82 The long-term effect of screening and lifestyle counseling on changes in physical activity and diet: the Inter99 Study - a randomized controlled trial. Int J Behav Nutr Phys Act 2015 0.76
83 Dietary ascorbic acid and subsequent change in body weight and waist circumference: associations may depend on genetic predisposition to obesity--a prospective study of three independent cohorts. Nutr J 2014 0.76
84 Does a population-based multi-factorial lifestyle intervention increase social inequality in dietary habits? The Inter99 study. Prev Med 2011 0.76
85 Effect of general health screening and lifestyle counselling on incidence of diabetes in general population: Inter99 randomised trial. Prev Med 2016 0.75
86 The effect of adding group-based counselling to individual lifestyle counselling on changes in dietary intake. The Inter99 study--a randomized controlled trial. Int J Behav Nutr Phys Act 2008 0.75
87 Carriers of a VEGFA enhancer polymorphism selectively binding CHOP/DDIT3 are predisposed to increased circulating levels of thyroid-stimulating hormone. J Med Genet 2016 0.75
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