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Evaluation of COPD (Chronic Obstructive Pulmonary Disease) to Longitudinally Identify Predictive Surrogate Endpoints (ECLIPSE)
Clinical Trial ID NCT00292552
PubWeight™ 118.66
‹?›
🔗 Visit the ClinicalTrials.gov page for NCT00292552
Top papers
Rank
Title
Journal
Year
PubWeight™
‹?›
1
Susceptibility to exacerbation in chronic obstructive pulmonary disease.
N Engl J Med
2010
15.07
2
Changes in forced expiratory volume in 1 second over time in COPD.
N Engl J Med
2011
5.69
3
Pulmonary arterial enlargement and acute exacerbations of COPD.
N Engl J Med
2012
5.54
4
Characterisation of COPD heterogeneity in the ECLIPSE cohort.
Respir Res
2010
5.17
5
Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE).
Eur Respir J
2008
4.53
6
Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.
PLoS Genet
2010
3.91
7
Variants in FAM13A are associated with chronic obstructive pulmonary disease.
Nat Genet
2010
3.44
8
Determinants of depression in the ECLIPSE chronic obstructive pulmonary disease cohort.
Am J Respir Crit Care Med
2010
2.80
9
Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype.
PLoS One
2012
2.52
10
Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis.
Lancet Respir Med
2014
2.28
11
Evaluation of serum CC-16 as a biomarker for COPD in the ECLIPSE cohort.
Thorax
2008
2.25
12
The presence and progression of emphysema in COPD as determined by CT scanning and biomarker expression: a prospective analysis from the ECLIPSE study.
Lancet Respir Med
2013
2.03
13
Inflammatory biomarkers improve clinical prediction of mortality in chronic obstructive pulmonary disease.
Am J Respir Crit Care Med
2012
1.99
14
A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13.
Hum Mol Genet
2011
1.98
15
Quantifying the extent of emphysema: factors associated with radiologists' estimations and quantitative indices of emphysema severity using the ECLIPSE cohort.
Acad Radiol
2011
1.88
16
Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease.
Am J Respir Crit Care Med
2013
1.79
17
Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease.
Am J Respir Crit Care Med
2012
1.72
18
Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease.
Thorax
2012
1.72
19
Identification of five chronic obstructive pulmonary disease subgroups with different prognoses in the ECLIPSE cohort using cluster analysis.
Ann Am Thorac Soc
2015
1.72
20
Predictors of objective cough frequency in chronic obstructive pulmonary disease.
Am J Respir Crit Care Med
2013
1.64
21
Association Between Interstitial Lung Abnormalities and All-Cause Mortality.
JAMA
2016
1.61
22
Serum surfactant protein D is steroid sensitive and associated with exacerbations of COPD.
Eur Respir J
2009
1.56
23
Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.
Am J Respir Crit Care Med
2012
1.49
24
COPD association and repeatability of blood biomarkers in the ECLIPSE cohort.
Respir Res
2011
1.43
25
Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema.
Am J Respir Crit Care Med
2010
1.36
26
Predicting outcomes from 6-minute walk distance in chronic obstructive pulmonary disease.
J Am Med Dir Assoc
2011
1.28
27
Sputum neutrophils as a biomarker in COPD: findings from the ECLIPSE study.
Respir Res
2010
1.26
28
Hospitalized exacerbations of COPD: risk factors and outcomes in the ECLIPSE cohort.
Chest
2015
1.25
29
Serum PARC/CCL-18 concentrations and health outcomes in chronic obstructive pulmonary disease.
Am J Respir Crit Care Med
2011
1.23
30
Physical activity monitoring in COPD: compliance and associations with clinical characteristics in a multicenter study.
Respir Med
2011
1.23
31
Should we view chronic obstructive pulmonary disease differently after ECLIPSE? A clinical perspective from the study team.
Am J Respir Crit Care Med
2014
1.20
32
Genome-wide association study of smoking behaviours in patients with COPD.
Thorax
2011
1.18
33
The association of genome-wide significant spirometric loci with chronic obstructive pulmonary disease susceptibility.
Am J Respir Cell Mol Biol
2011
1.17
34
Eosinophilic inflammation in COPD: prevalence and clinical characteristics.
Eur Respir J
2014
1.17
35
Genetics of sputum gene expression in chronic obstructive pulmonary disease.
PLoS One
2011
1.11
36
Respiratory system impedance with impulse oscillometry in healthy and COPD subjects: ECLIPSE baseline results.
Respir Med
2011
1.11
37
Factors associated with change in exacerbation frequency in COPD.
Respir Res
2013
1.08
38
Elevated airway purines in COPD.
Chest
2011
1.07
39
Targeted metabolomics identifies perturbations in amino acid metabolism that sub-classify patients with COPD.
Mol Biosyst
2012
1.02
40
A Genome-Wide Association Study of Emphysema and Airway Quantitative Imaging Phenotypes.
Am J Respir Crit Care Med
2015
1.02
41
An aberrant leukotriene A4 hydrolase-proline-glycine-proline pathway in the pathogenesis of chronic obstructive pulmonary disease.
Am J Respir Crit Care Med
2014
0.95
42
Non-emphysematous chronic obstructive pulmonary disease is associated with diabetes mellitus.
BMC Pulm Med
2014
0.93
43
Dissecting direct and indirect genetic effects on chronic obstructive pulmonary disease (COPD) susceptibility.
Hum Genet
2013
0.92
44
Identification of FGF7 as a novel susceptibility locus for chronic obstructive pulmonary disease.
Thorax
2011
0.91
45
Genome-wide association analysis of body mass in chronic obstructive pulmonary disease.
Am J Respir Cell Mol Biol
2010
0.90
46
Gene expression analysis uncovers novel hedgehog interacting protein (HHIP) effects in human bronchial epithelial cells.
Genomics
2013
0.89
47
Altered gene expression in blood and sputum in COPD frequent exacerbators in the ECLIPSE cohort.
PLoS One
2014
0.86
48
Vitamin D, vitamin D binding protein, lung function and structure in COPD.
Respir Med
2013
0.84
49
One-year change in health status and subsequent outcomes in COPD.
Thorax
2015
0.84
50
Genetic association between human chitinases and lung function in COPD.
Hum Genet
2011
0.82
51
DNAH5 is associated with total lung capacity in chronic obstructive pulmonary disease.
Respir Res
2014
0.82
52
Sarcopenic Obesity, Functional Outcomes, and Systemic Inflammation in Patients With Chronic Obstructive Pulmonary Disease.
J Am Med Dir Assoc
2016
0.81
53
Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary disease.
Respir Res
2014
0.80
54
A diVIsive Shuffling Approach (VIStA) for gene expression analysis to identify subtypes in Chronic Obstructive Pulmonary Disease.
BMC Syst Biol
2014
0.80
55
Analyzing networks of phenotypes in complex diseases: methodology and applications in COPD.
BMC Syst Biol
2014
0.80
56
The Effect of Statins on Blood Gene Expression in COPD.
PLoS One
2015
0.79
57
On the follow-up of genome-wide association studies: an overall test for the most promising SNPs.
Genet Epidemiol
2011
0.79
58
Analysis of chloroformate-derivatised amino acids, dipeptides and polyamines by LC-MS/MS.
J Chromatogr B Analyt Technol Biomed Life Sci
2013
0.78
59
Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease.
Am J Respir Cell Mol Biol
2014
0.78
60
Early response to inhaled bronchodilators and corticosteroids as a predictor of 12-month treatment responder status and COPD exacerbations.
Int J Chron Obstruct Pulmon Dis
2016
0.78
61
Nitric oxide synthase polymorphisms, gene expression and lung function in chronic obstructive pulmonary disease.
BMC Pulm Med
2013
0.77
62
COPD subtypes identified by network-based clustering of blood gene expression.
Genomics
2016
0.77
63
Beyond GWAS in COPD: probing the landscape between gene-set associations, genome-wide associations and protein-protein interaction networks.
Hum Hered
2014
0.77
64
IREB2 and GALC are associated with pulmonary artery enlargement in chronic obstructive pulmonary disease.
Am J Respir Cell Mol Biol
2015
0.77
65
A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
BMC Genet
2015
0.77
66
High levels of biomarkers of collagen remodeling are associated with increased mortality in COPD - results from the ECLIPSE study.
Respir Res
2016
0.76
67
The Effect of Different Case Definitions of Current Smoking on the Discovery of Smoking-Related Blood Gene Expression Signatures in Chronic Obstructive Pulmonary Disease.
Nicotine Tob Res
2016
0.76
68
Identifying a Deletion Affecting Total Lung Capacity Among Subjects in the COPDGene Study Cohort.
Genet Epidemiol
2015
0.76
69
Tiotropium and Salmeterol in COPD Patients at Risk of Exacerbations: A Post Hoc Analysis from POET-COPD(®).
Adv Ther
2015
0.76
70
DNA methylation profiling in human lung tissue identifies genes associated with COPD.
Epigenetics
2016
0.76
71
Examining fatigue in COPD: development, validity and reliability of a modified version of FACIT-F scale.
Health Qual Life Outcomes
2012
0.76
72
Long-term Course of Depression Trajectories in Patients With COPD: A 3-Year Follow-up Analysis of the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints Cohort.
Chest
2016
0.75
73
SABRE: a method for assessing the stability of gene modules in complex tissues and subject populations.
BMC Bioinformatics
2016
0.75
74
Effect of inhaled corticosteroids on blood eosinophil count in steroid-naïve patients with COPD.
BMJ Open Respir Res
2016
0.75
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