| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada.
|
J Natl Cancer Inst
|
2000
|
133.74
|
|
2
|
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer.
|
N Engl J Med
|
2004
|
49.02
|
|
3
|
Isolation of putative progenitor endothelial cells for angiogenesis.
|
Science
|
1997
|
30.27
|
|
4
|
Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy.
|
Science
|
2005
|
23.44
|
|
5
|
Hypoxia--a key regulatory factor in tumour growth.
|
Nat Rev Cancer
|
2002
|
20.51
|
|
6
|
Exercise capacity and mortality among men referred for exercise testing.
|
N Engl J Med
|
2002
|
14.30
|
|
7
|
A simple method to assess exercise behavior in the community.
|
Can J Appl Sport Sci
|
1985
|
13.27
|
|
8
|
Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy.
|
Nat Med
|
2001
|
10.37
|
|
9
|
Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization.
|
Nat Med
|
1999
|
10.16
|
|
10
|
Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases.
|
Cancer Cell
|
2004
|
8.78
|
|
11
|
Reliability and validity of the Functional Assessment of Cancer Therapy-Breast quality-of-life instrument.
|
J Clin Oncol
|
1997
|
7.79
|
|
12
|
Influences of cardiorespiratory fitness and other precursors on cardiovascular disease and all-cause mortality in men and women.
|
JAMA
|
1996
|
7.45
|
|
13
|
Transplantation of ex vivo expanded endothelial progenitor cells for therapeutic neovascularization.
|
Proc Natl Acad Sci U S A
|
2000
|
6.59
|
|
14
|
Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors.
|
Cancer Res
|
2004
|
5.65
|
|
15
|
Meeting highlights: International Consensus Panel on the Treatment of Primary Breast Cancer. Seventh International Conference on Adjuvant Therapy of Primary Breast Cancer.
|
J Clin Oncol
|
2001
|
5.31
|
|
16
|
Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer.
|
J Clin Oncol
|
2005
|
5.27
|
|
17
|
Effect of exercise on coronary endothelial function in patients with coronary artery disease.
|
N Engl J Med
|
2000
|
4.43
|
|
18
|
Addition of bevacizumab to bolus fluorouracil and leucovorin in first-line metastatic colorectal cancer: results of a randomized phase II trial.
|
J Clin Oncol
|
2005
|
4.32
|
|
19
|
HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway.
|
J Clin Invest
|
2001
|
4.11
|
|
20
|
Regular physical activity improves endothelial function in patients with coronary artery disease by increasing phosphorylation of endothelial nitric oxide synthase.
|
Circulation
|
2003
|
3.86
|
|
21
|
Pathology: cancer cells compress intratumour vessels.
|
Nature
|
2004
|
3.60
|
|
22
|
Randomized controlled trial of exercise training in postmenopausal breast cancer survivors: cardiopulmonary and quality of life outcomes.
|
J Clin Oncol
|
2003
|
3.56
|
|
23
|
Effect of exercise training on endothelium-derived nitric oxide function in humans.
|
J Physiol
|
2004
|
3.48
|
|
24
|
Tumour biology: herceptin acts as an anti-angiogenic cocktail.
|
Nature
|
2002
|
3.40
|
|
25
|
Resistance exercise in men receiving androgen deprivation therapy for prostate cancer.
|
J Clin Oncol
|
2003
|
3.07
|
|
26
|
Transplanted cord blood-derived endothelial precursor cells augment postnatal neovascularization.
|
J Clin Invest
|
2000
|
2.96
|
|
27
|
Assessment of leisure time exercise behavior by self-report: a concurrent validity study.
|
Can J Public Health
|
1987
|
2.94
|
|
28
|
Regular physical exercise corrects endothelial dysfunction and improves exercise capacity in patients with chronic heart failure.
|
Circulation
|
1998
|
2.90
|
|
29
|
The Functional Assessment of Cancer Therapy-Anemia (FACT-An) Scale: a new tool for the assessment of outcomes in cancer anemia and fatigue.
|
Semin Hematol
|
1997
|
2.68
|
|
30
|
Physical training increases endothelial progenitor cells, inhibits neointima formation, and enhances angiogenesis.
|
Circulation
|
2003
|
2.59
|
|
31
|
Overexpression of hypoxia-inducible factor 1alpha is associated with an unfavorable prognosis in lymph node-positive breast cancer.
|
Clin Cancer Res
|
2002
|
2.57
|
|
32
|
Bone marrow-derived endothelial progenitor cells participate in cerebral neovascularization after focal cerebral ischemia in the adult mouse.
|
Circ Res
|
2002
|
2.45
|
|
33
|
HMG-CoA reductase inhibitor mobilizes bone marrow--derived endothelial progenitor cells.
|
J Clin Invest
|
2001
|
2.20
|
|
34
|
Structured exercise improves physical functioning in women with stages I and II breast cancer: results of a randomized controlled trial.
|
J Clin Oncol
|
2001
|
2.16
|
|
35
|
Differential prognostic impact of hypoxia induced and diffuse HIF-1alpha expression in invasive breast cancer.
|
J Clin Pathol
|
2005
|
2.10
|
|
36
|
Fundamentals of endothelial function for the clinical cardiologist.
|
Circulation
|
2002
|
2.07
|
|
37
|
Limited penetration of anticancer drugs through tumor tissue: a potential cause of resistance of solid tumors to chemotherapy.
|
Clin Cancer Res
|
2002
|
2.05
|
|
38
|
Effects of an oncologist's recommendation to exercise on self-reported exercise behavior in newly diagnosed breast cancer survivors: a single-blind, randomized controlled trial.
|
Ann Behav Med
|
2004
|
2.04
|
|
39
|
Hypoxia-inducible factors HIF-1alpha and HIF-2alpha in head and neck cancer: relationship to tumor biology and treatment outcome in surgically resected patients.
|
Cancer Res
|
2002
|
1.84
|
|
40
|
Remodeling of the extracellular matrix through overexpression of collagen VI contributes to cisplatin resistance in ovarian cancer cells.
|
Cancer Cell
|
2003
|
1.81
|
|
41
|
Polychemotherapy for early breast cancer: an overview of the randomised clinical trials with quality-adjusted survival analysis.
|
Lancet
|
2001
|
1.79
|
|
42
|
Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance.
|
Mol Cell Biol
|
2004
|
1.77
|
|
43
|
Cathepsin L is required for endothelial progenitor cell-induced neovascularization.
|
Nat Med
|
2005
|
1.69
|
|
44
|
A systems approach to cancer therapy. (Antioncogenics + standard cytotoxics-->mechanism(s) of interaction).
|
Cancer Metastasis Rev
|
1996
|
1.68
|
|
45
|
Hypoxia increases resistance of human pancreatic cancer cells to apoptosis induced by gemcitabine.
|
Clin Cancer Res
|
2004
|
1.68
|
|
46
|
Changes in vegetable and fruit consumption and awareness among US adults: results of the 1991 and 1997 5 A Day for Better Health Program surveys.
|
J Am Diet Assoc
|
2002
|
1.67
|
|
47
|
Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration.
|
J Clin Invest
|
2002
|
1.67
|
|
48
|
Exercise counseling and programming preferences of cancer survivors.
|
Cancer Pract
|
2002
|
1.59
|
|
49
|
Exercise acutely increases circulating endothelial progenitor cells and monocyte-/macrophage-derived angiogenic cells.
|
J Am Coll Cardiol
|
2004
|
1.50
|
|
50
|
Increase of circulating endothelial progenitor cells in patients with coronary artery disease after exercise-induced ischemia.
|
Arterioscler Thromb Vasc Biol
|
2004
|
1.45
|
|
51
|
Design of FRESH START: a randomized trial of exercise and diet among cancer survivors.
|
Med Sci Sports Exerc
|
2003
|
1.40
|
|
52
|
Transplanted human bone marrow contributes to vascular endothelium.
|
Proc Natl Acad Sci U S A
|
2004
|
1.39
|
|
53
|
Nitric oxide-mediated metabolic regulation during exercise: effects of training in health and cardiovascular disease.
|
FASEB J
|
2000
|
1.33
|
|
54
|
Leading the Way in Exercise and Diet (Project LEAD): intervening to improve function among older breast and prostate cancer survivors.
|
Control Clin Trials
|
2003
|
1.29
|
|
55
|
Tumor physiology and drug resistance.
|
Cancer Metastasis Rev
|
2001
|
1.23
|
|
56
|
Clinical aspects of drug delivery to tumors.
|
J Control Release
|
2002
|
1.20
|
|
57
|
Time course of improved flow-mediated dilation after short-term exercise training.
|
Med Sci Sports Exerc
|
2003
|
1.15
|
|
58
|
Hypoxia-inducible factor 1 alpha in high-risk breast cancer: an independent prognostic parameter?
|
Breast Cancer Res
|
2004
|
1.14
|
|
59
|
Regional and whole-body markers of nitric oxide production following hyperemic stimuli.
|
Free Radic Biol Med
|
2005
|
1.13
|
|
60
|
Systemic therapy for treating locoregional recurrence in women with breast cancer.
|
Cochrane Database Syst Rev
|
2001
|
1.10
|
|
61
|
Effects of exercise training on antitumor efficacy of doxorubicin in MDA-MB-231 breast cancer xenografts.
|
Clin Cancer Res
|
2005
|
1.09
|
|
62
|
Effect of exercise training on endothelial function in men with coronary artery disease.
|
Am J Cardiol
|
2004
|
1.07
|
|
63
|
Exercise training improves conduit vessel function in patients with coronary artery disease.
|
J Appl Physiol (1985)
|
2003
|
1.06
|
|
64
|
Exercise discussions during cancer treatment consultations.
|
Cancer Pract
|
2002
|
1.05
|
|
65
|
Chemotherapy alone versus endocrine therapy alone for metastatic breast cancer.
|
Cochrane Database Syst Rev
|
2003
|
1.05
|
|
66
|
Hypoxia and oxidative stress. Tumour hypoxia--therapeutic considerations.
|
Breast Cancer Res
|
2001
|
1.02
|
|
67
|
Modulation of circulating angiogenic factors and tumor biology by aerobic training in breast cancer patients receiving neoadjuvant chemotherapy.
|
Cancer Prev Res (Phila)
|
2013
|
0.99
|
|
68
|
Expression of HIF-1alpha in human tumours.
|
J Clin Pathol
|
2005
|
0.97
|
|
69
|
Does the theory of planned behavior mediate the effects of an oncologist's recommendation to exercise in newly diagnosed breast cancer survivors? Results from a randomized controlled trial.
|
Health Psychol
|
2005
|
0.97
|
|
70
|
Nitric oxide as a metabolic regulator during exercise: effects of training in health and disease.
|
Clin Exp Pharmacol Physiol
|
2000
|
0.95
|
|
71
|
Hypoxia induced resistance to doxorubicin in prostate cancer cells is inhibited by low concentrations of glyceryl trinitrate.
|
J Urol
|
2003
|
0.94
|
|
72
|
Exercise training enhances vasodilation responses to vascular endothelial growth factor in porcine coronary arterioles exposed to chronic coronary occlusion.
|
Circulation
|
2004
|
0.91
|
|
73
|
Exercise delays allogeneic tumor growth and reduces intratumoral inflammation and vascularization.
|
J Appl Physiol (1985)
|
2004
|
0.87
|
|
74
|
VEGF-D and HIF-1alpha in breast cancer.
|
J Clin Pathol
|
2005
|
0.84
|
|
75
|
Effects of exercise training on vascular function and myocardial perfusion.
|
Cardiol Clin
|
2001
|
0.83
|
|
76
|
Forearm vasoreactivity in type 1diabetic subjects.
|
Can J Appl Physiol
|
2001
|
0.81
|
|
77
|
[Standards, Options and Recommendations for the management of ductal carcinoma in situ of the breast (DCIS): update 2004].
|
Bull Cancer
|
2005
|
0.79
|
|
78
|
Exercise and endothelial function.
|
Circulation
|
2000
|
0.76
|