Statins for the Early Treatment of Sepsis (SETS)

Clinical Trial ID NCT00528580

PubWeight™ 10.65‹?›

🔗 Visit the ClinicalTrials.gov page for NCT00528580

Top papers

Rank Title Journal Year PubWeight™‹?›
1 American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 1992 20.79
2 Statins and sepsis in patients with cardiovascular disease: a population-based cohort analysis. Lancet 2006 4.42
3 Statins and outcomes in patients admitted to hospital with community acquired pneumonia: population based prospective cohort study. BMJ 2006 3.62
4 The effect of statins on mortality in patients with bacteremia. Clin Infect Dis 2001 3.02
5 Prior statin therapy is associated with a decreased rate of severe sepsis. Circulation 2004 2.82
6 Statin use and sepsis events [corrected] in patients with chronic kidney disease. JAMA 2007 2.69
7 High-dose, short-course levofloxacin for community-acquired pneumonia: a new treatment paradigm. Clin Infect Dis 2003 2.63
8 A novel anti-inflammatory role for simvastatin in inflammatory arthritis. J Immunol 2003 2.37
9 Statin use and mortality within 180 days after bacteremia: a population-based cohort study. Crit Care Med 2006 2.16
10 Simvastatin attenuates vascular leak and inflammation in murine inflammatory lung injury. Am J Physiol Lung Cell Mol Physiol 2005 2.13
11 Statin treatment after onset of sepsis in a murine model improves survival. Circulation 2005 2.08
12 Simvastatin improves sepsis-induced mortality and acute kidney injury via renal vascular effects. Kidney Int 2006 1.83
13 Understanding the potential role of statins in pneumonia and sepsis. Crit Care Med 2011 1.77
14 In the critically ill patient, diabetes predicts mortality independent of statin therapy but is not associated with acute lung injury: a cohort study. Crit Care Med 2012 1.53
15 Lovastatin inhibits brain endothelial cell Rho-mediated lymphocyte migration and attenuates experimental autoimmune encephalomyelitis. FASEB J 2003 1.38
16 Statin use and risk of community acquired pneumonia in older people: population based case-control study. BMJ 2009 1.30
17 Simvastatin ameliorates injury in an experimental model of lung ischemia-reperfusion. J Thorac Cardiovasc Surg 2003 1.16
18 Association of statin therapy and increased survival in patients with multiple organ dysfunction syndrome. Intensive Care Med 2006 1.15
19 Statins, inflammation and kidney disease. Nat Rev Nephrol 2011 1.04
20 Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury. N Engl J Med 2000 1.01
21 Systematic review and meta-analysis on the association between outpatient statins use and infectious disease-related mortality. PLoS One 2012 0.95
22 Lovastatin for adult patients with dengue: protocol for a randomised controlled trial. Trials 2012 0.93
23 Effects of discontinuing or continuing ongoing statin therapy in severe sepsis and septic shock: a retrospective cohort study. Crit Care 2011 0.84
24 To JUPITER and beyond: statins, inflammation, and primary prevention. Crit Care 2010 0.82
25 Association between statin therapy and outcomes in critically ill patients: a nested cohort study. BMC Clin Pharmacol 2011 0.82
26 Statins role in the prevention and treatment of sepsis. Pharmacol Res 2014 0.80
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