Examining the Genetic Factors That May Cause Chronic Obstructive Pulmonary Disease (COPD) (COPDGene)

Clinical Trial ID NCT00608764

PubWeight™ 69.98‹?›

🔗 Visit the ClinicalTrials.gov page for NCT00608764

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Pulmonary arterial enlargement and acute exacerbations of COPD. N Engl J Med 2012 5.54
2 Lung volumes and emphysema in smokers with interstitial lung abnormalities. N Engl J Med 2011 4.75
3 GOLD 2011 disease severity classification in COPDGene: a prospective cohort study. Lancet Respir Med 2012 3.98
4 Chronic obstructive pulmonary disease exacerbations in the COPDGene study: associated radiologic phenotypes. Radiology 2011 3.30
5 The clinical features of the overlap between COPD and asthma. Respir Res 2011 2.29
6 Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis. Lancet Respir Med 2014 2.28
7 The chronic bronchitic phenotype of COPD: an analysis of the COPDGene Study. Chest 2011 2.14
8 A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13. Hum Mol Genet 2011 1.98
9 Interstitial lung abnormalities and reduced exercise capacity. Am J Respir Crit Care Med 2012 1.80
10 Genome-wide study of percent emphysema on computed tomography in the general population. The Multi-Ethnic Study of Atherosclerosis Lung/SNP Health Association Resource Study. Am J Respir Crit Care Med 2014 1.80
11 Clinical and radiographic predictors of GOLD-unclassified smokers in the COPDGene study. Am J Respir Crit Care Med 2011 1.76
12 Racial differences in quality of life in patients with COPD. Chest 2011 1.64
13 Genome-wide association identifies regulatory Loci associated with distinct local histogram emphysema patterns. Am J Respir Crit Care Med 2014 1.57
14 β-Blockers are associated with a reduction in COPD exacerbations. Thorax 2015 1.48
15 Statins and pulmonary fibrosis: the potential role of NLRP3 inflammasome activation. Am J Respir Crit Care Med 2012 1.27
16 The clinical impact of non-obstructive chronic bronchitis in current and former smokers. Respir Med 2013 1.23
17 Clinical and radiographic correlates of hypoxemia and oxygen therapy in the COPDGene study. Respir Med 2011 1.12
18 Epidemiology, radiology, and genetics of nicotine dependence in COPD. Respir Res 2011 1.10
19 Epidemiology, genetics, and subtyping of preserved ratio impaired spirometry (PRISm) in COPDGene. Respir Res 2014 1.06
20 Association between airway caliber changes with lung inflation and emphysema assessed by volumetric CT scan in subjects with COPD. Chest 2011 1.03
21 A Genome-Wide Association Study of Emphysema and Airway Quantitative Imaging Phenotypes. Am J Respir Crit Care Med 2015 1.02
22 Effect of emphysema on CT scan measures of airway dimensions in smokers. Chest 2013 0.97
23 Racial differences in CT phenotypes in COPD. COPD 2013 0.95
24 Pulmonary artery enlargement is associated with right ventricular dysfunction and loss of blood volume in small pulmonary vessels in chronic obstructive pulmonary disease. Circ Cardiovasc Imaging 2015 0.93
25 Non-emphysematous chronic obstructive pulmonary disease is associated with diabetes mellitus. BMC Pulm Med 2014 0.93
26 Exome Sequencing Analysis in Severe, Early-Onset Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med 2016 0.92
27 Generative Method to Discover Genetically Driven Image Biomarkers. Inf Process Med Imaging 2015 0.91
28 A simplified score to quantify comorbidity in COPD. PLoS One 2014 0.89
29 Clinical, physiologic, and radiographic factors contributing to development of hypoxemia in moderate to severe COPD: a cohort study. BMC Pulm Med 2016 0.87
30 Risk factors for COPD exacerbations in inhaled medication users: the COPDGene study biannual longitudinal follow-up prospective cohort. BMC Pulm Med 2016 0.86
31 Impact of self-reported gastroesophageal reflux disease in subjects from COPDGene cohort. Respir Res 2014 0.84
32 Childhood pneumonia increases risk for chronic obstructive pulmonary disease: the COPDGene study. Respir Res 2015 0.84
33 DNAH5 is associated with total lung capacity in chronic obstructive pulmonary disease. Respir Res 2014 0.82
34 Exome Array Analysis Identifies a Common Variant in IL27 Associated with Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med 2016 0.81
35 Spherical Topic Models for Imaging Phenotype Discovery in Genetic Studies. Bayesian Graph Models Biomed Imaging 2015 0.81
36 Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary disease. Respir Res 2014 0.80
37 Chronic obstructive pulmonary disease: respiratory review of 2013. Tuberc Respir Dis (Seoul) 2014 0.79
38 Reproducibility of NIRS assessment of muscle oxidative capacity in smokers with and without COPD. Respir Physiol Neurobiol 2016 0.79
39 CT-derived Biomechanical Metrics Improve Agreement Between Spirometry and Emphysema. Acad Radiol 2016 0.78
40 Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol 2014 0.78
41 Phenotypic and genetic heterogeneity among subjects with mild airflow obstruction in COPDGene. Respir Med 2014 0.78
42 A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. BMC Genet 2015 0.77
43 Age-Related Differences in Health-Related Quality of Life in COPD: An Analysis of the COPDGene and SPIROMICS Cohorts. Chest 2015 0.77
44 Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD. PLoS Genet 2016 0.77
45 IREB2 and GALC are associated with pulmonary artery enlargement in chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol 2015 0.77
46 Childhood-onset asthma in smokers. association between CT measures of airway size, lung function, and chronic airflow obstruction. Ann Am Thorac Soc 2014 0.77
47 Pneumothorax risk factors in smokers with and without chronic obstructive pulmonary disease. Ann Am Thorac Soc 2014 0.77
48 Disproportionate contribution of right middle lobe to emphysema and gas trapping on computed tomography. PLoS One 2014 0.77
49 Identifying a Deletion Affecting Total Lung Capacity Among Subjects in the COPDGene Study Cohort. Genet Epidemiol 2015 0.76
50 DNA methylation profiling in human lung tissue identifies genes associated with COPD. Epigenetics 2016 0.76
51 Susceptibility to Childhood Pneumonia: A Genome-Wide Analysis. Am J Respir Cell Mol Biol 2016 0.75
52 Arterial and Venous Pulmonary Vascular Morphology and Their Relationship to Findings in Cardiac Magnetic Resonance Imaging in Smokers. J Comput Assist Tomogr 2016 0.75
53 Hemizygous Deletion on Chromosome 3p26.1 Is Associated with Heavy Smoking among African American Subjects in the COPDGene Study. PLoS One 2016 0.75
54 Acute Exacerbations and Lung Function Loss in Smokers With and Without COPD. Am J Respir Crit Care Med 2016 0.75
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