Global Study to Assess the Safety and Effectiveness of Edoxaban (DU-176b) vs Standard Practice of Dosing With Warfarin in Patients With Atrial Fibrillation (EngageAFTIMI48)

Clinical Trial ID NCT00781391

PubWeight™ 31.87‹?›

🔗 Visit the ClinicalTrials.gov page for NCT00781391

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Edoxaban versus warfarin in patients with atrial fibrillation. N Engl J Med 2013 7.70
2 Genetics and the clinical response to warfarin and edoxaban: findings from the randomised, double-blind ENGAGE AF-TIMI 48 trial. Lancet 2015 2.57
3 Association between edoxaban dose, concentration, anti-Factor Xa activity, and outcomes: an analysis of data from the randomised, double-blind ENGAGE AF-TIMI 48 trial. Lancet 2015 2.04
4 Evaluation of the novel factor Xa inhibitor edoxaban compared with warfarin in patients with atrial fibrillation: design and rationale for the Effective aNticoaGulation with factor xA next GEneration in Atrial Fibrillation-Thrombolysis In Myocardial Infarction study 48 (ENGAGE AF-TIMI 48). Am Heart J 2010 1.91
5 Transition of patients from blinded study drug to open-label anticoagulation: the ENGAGE AF-TIMI 48 trial. J Am Coll Cardiol 2014 1.45
6 The discovery and development of rivaroxaban, an oral, direct factor Xa inhibitor. Nat Rev Drug Discov 2010 1.33
7 Update on anti-coagulation in atrial fibrillation. QJM 2011 1.28
8 Impact of Renal Function on Outcomes With Edoxaban in the ENGAGE AF-TIMI 48 Trial. Circulation 2016 1.07
9 Left atrial structure and function in atrial fibrillation: ENGAGE AF-TIMI 48. Eur Heart J 2013 1.03
10 New oral anticoagulants may be particularly useful for asian stroke patients. J Stroke 2014 1.00
11 Modelling and simulation of edoxaban exposure and response relationships in patients with atrial fibrillation. Thromb Haemost 2012 0.97
12 Cerebrovascular events in 21 105 patients with atrial fibrillation randomized to edoxaban versus warfarin: Effective Anticoagulation with Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48. Stroke 2014 0.87
13 A randomized trial of the safety, pharmacokinetics and pharmacodynamics of edoxaban, an oral factor Xa inhibitor, following a switch from warfarin. Br J Clin Pharmacol 2013 0.85
14 Review of atrial fibrillation outcome trials of oral anticoagulant and antiplatelet agents. Europace 2012 0.84
15 Concomitant Use of Single Antiplatelet Therapy With Edoxaban or Warfarin in Patients With Atrial Fibrillation: Analysis From the ENGAGE AF-TIMI48 Trial. J Am Heart Assoc 2016 0.80
16 Efficacy and Safety of Edoxaban in Elderly Patients With Atrial Fibrillation in the ENGAGE AF-TIMI 48 Trial. J Am Heart Assoc 2016 0.78
17 Anticoagulant and antiplatelet therapy in patients with atrial fibrillation and coronary artery disease. Thrombosis 2012 0.78
18 Cardiovascular Biomarker Score and Clinical Outcomes in Patients With Atrial Fibrillation: A Subanalysis of the ENGAGE AF-TIMI 48 Randomized Clinical Trial. JAMA Cardiol 2016 0.78
19 Edoxaban Versus Warfarin in Atrial Fibrillation Patients at Risk of Falling: ENGAGE AF-TIMI 48 Analysis. J Am Coll Cardiol 2016 0.77
20 Use of Direct Oral Anticoagulants in Patients With Atrial Fibrillation and Valvular Heart Lesions. J Am Heart Assoc 2016 0.77
21 Efficacy and safety of novel anticoagulants compared with established agents. Ther Adv Hematol 2011 0.77
22 Potential role of new anticoagulants for prevention and treatment of venous thromboembolism in cancer patients. Vasc Health Risk Manag 2013 0.76
23 Outcomes With Edoxaban Versus Warfarin in Patients With Previous Cerebrovascular Events: Findings From ENGAGE AF-TIMI 48 (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48). Stroke 2016 0.75
24 The need for multicentre cardiovascular clinical trials in Asia. Nat Rev Cardiol 2013 0.75
25 Improving anticoagulation management in patients with atrial fibrillation. P T 2013 0.75
26 Sudden Cardiac Death in Patients With Atrial Fibrillation: Insights From the ENGAGE AF-TIMI 48 Trial. J Am Heart Assoc 2016 0.75
27 Edoxaban. Hosp Pharm 2015 0.75
28 Stroke prevention in atrial fibrillation: latest clinical trials and guidelines. Pharmaceuticals (Basel) 2012 0.75
29 The Prognostic Significance of Cardiac Structure and Function in Atrial Fibrillation: The ENGAGE AF-TIMI 48 Echocardiographic Substudy. J Am Soc Echocardiogr 2016 0.75
30 Stroke and Mortality Risk in Patients With Various Patterns of Atrial Fibrillation: Results From the ENGAGE AF-TIMI 48 Trial (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48). Circ Arrhythm Electrophysiol 2017 0.75
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