PubRank

Progesterone for the Treatment of Traumatic Brain Injury III (ProTECT)

Clinical Trial ID NCT00822900

PubWeight™ 23.27‹?›

🔗 Visit the ClinicalTrials.gov page for NCT00822900

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Very early administration of progesterone for acute traumatic brain injury. N Engl J Med 2014 3.20
2 Progesterone in experimental permanent stroke: a dose-response and therapeutic time-window study. Brain 2013 1.49
3 Patients' perspectives of enrollment in research without consent: the patients' experiences in emergency research-progesterone for the treatment of traumatic brain injury study. Crit Care Med 2015 1.43
4 Pharmacotherapy of traumatic brain injury: state of the science and the road forward: report of the Department of Defense Neurotrauma Pharmacology Workgroup. J Neurotrauma 2014 1.31
5 Progesterone treatment normalizes the levels of cell proliferation and cell death in the dentate gyrus of the hippocampus after traumatic brain injury. Exp Neurol 2011 1.01
6 Progesterone receptors: a key for neuroprotection in experimental stroke. Endocrinology 2012 0.99
7 Progesterone attenuates hemorrhagic transformation after delayed tPA treatment in an experimental model of stroke in rats: involvement of the VEGF-MMP pathway. J Cereb Blood Flow Metab 2013 0.97
8 Post-stroke infections exacerbate ischemic brain injury in middle-aged rats: immunomodulation and neuroprotection by progesterone. Neuroscience 2012 0.91
9 Is progesterone a worthy candidate as a novel therapy for traumatic brain injury? Dialogues Clin Neurosci 2011 0.91
10 Progesterone protects blood-brain barrier function and improves neurological outcome following traumatic brain injury in rats. Exp Ther Med 2014 0.88
11 Allopregnanolone levels are reduced in temporal cortex in patients with Alzheimer's disease compared to cognitively intact control subjects. Biochim Biophys Acta 2010 0.87
12 Neuroprotective effects of progesterone in traumatic brain injury: blunted in vivo neutrophil activation at the blood-brain barrier. Am J Surg 2013 0.84
13 NAD(P)H:quinone oxidoreductase 1 is induced by progesterone in cardiomyocytes. Cardiovasc Toxicol 2012 0.83
14 Delayed progesterone treatment reduces brain infarction and improves functional outcomes after ischemic stroke: a time-window study in middle-aged rats. J Cereb Blood Flow Metab 2013 0.82
15 The neuroprotective effects of progesterone on traumatic brain injury: current status and future prospects. Acta Pharmacol Sin 2013 0.82
16 Progesterone for neuroprotection in pediatric traumatic brain injury. Pediatr Crit Care Med 2015 0.82
17 Progesterone and vitamin d hormone as a biologic treatment of traumatic brain injury in the aged. PM R 2011 0.82
18 Anti-inflammatory effects of progesterone in lipopolysaccharide-stimulated BV-2 microglia. PLoS One 2014 0.81
19 Therapeutic effects of progesterone and its metabolites in traumatic brain injury may involve non-classical signaling mechanisms. Front Neurosci 2013 0.79
20 Studying community consultation in exception from informed consent trials. Crit Care Med 2014 0.78
21 Progesterone treatment shows benefit in a pediatric model of moderate to severe bilateral brain injury. PLoS One 2014 0.77
22 Progesterone in transient ischemic stroke: a dose-response study. Psychopharmacology (Berl) 2014 0.76
23 Architecture design of a generic centralized adjudication module integrated in a web-based clinical trial management system. Clin Trials 2015 0.75
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