Controlled Myelofibrosis Study With Oral Janus-associated Kinase (JAK) Inhibitor Treatment-II: The COMFORT-II Trial

Clinical Trial ID NCT00934544

PubWeight™ 32.21‹?›

🔗 Visit the ClinicalTrials.gov page for NCT00934544

Top papers

Rank Title Journal Year PubWeight™‹?›
1 JAK inhibition with ruxolitinib versus best available therapy for myelofibrosis. N Engl J Med 2012 10.07
2 Philadelphia-negative classical myeloproliferative neoplasms: critical concepts and management recommendations from European LeukemiaNet. J Clin Oncol 2011 3.83
3 Three-year efficacy, safety, and survival findings from COMFORT-II, a phase 3 study comparing ruxolitinib with best available therapy for myelofibrosis. Blood 2013 2.60
4 Efficacy, safety and survival with ruxolitinib in patients with myelofibrosis: results of a median 2-year follow-up of COMFORT-I. Haematologica 2013 1.67
5 Efficacy, safety, and survival with ruxolitinib in patients with myelofibrosis: results of a median 3-year follow-up of COMFORT-I. Haematologica 2015 1.32
6 Biology and clinical management of myeloproliferative neoplasms and development of the JAK inhibitor ruxolitinib. Curr Med Chem 2012 1.16
7 A pooled analysis of overall survival in COMFORT-I and COMFORT-II, 2 randomized phase III trials of ruxolitinib for the treatment of myelofibrosis. Haematologica 2015 1.10
8 Resolution of bone marrow fibrosis in a patient receiving JAK1/JAK2 inhibitor treatment with ruxolitinib. Haematologica 2013 1.02
9 Myelofibrosis-associated complications: pathogenesis, clinical manifestations, and effects on outcomes. Int J Gen Med 2014 0.98
10 Comparison of placebo and best available therapy for the treatment of myelofibrosis in the phase 3 COMFORT studies. Haematologica 2013 0.97
11 Rapid and long-lasting decrease of T-regulatory cells in patients with myelofibrosis treated with ruxolitinib. Leukemia 2013 0.95
12 Ruxolitinib for the treatment of myelofibrosis: its clinical potential. Ther Clin Risk Manag 2012 0.93
13 Role of tyrosine-kinase inhibitors in myeloproliferative neoplasms: comparative lessons learned. Onco Targets Ther 2016 0.88
14 The evolving treatment paradigm in myelofibrosis. Leuk Lymphoma 2012 0.84
15 The use of erythropoiesis-stimulating agents with ruxolitinib in patients with myelofibrosis in COMFORT-II: an open-label, phase 3 study assessing efficacy and safety of ruxolitinib versus best available therapy in the treatment of myelofibrosis. Exp Hematol Oncol 2015 0.84
16 Symptom burden and splenomegaly in patients with myelofibrosis in the United States: a retrospective medical record review. Cancer Med 2013 0.81
17 Definition and management of ruxolitinib treatment failure in myelofibrosis. Blood Cancer J 2014 0.80
18 The arrival of JAK inhibitors: advancing the treatment of immune and hematologic disorders. BioDrugs 2013 0.78
19 Emerging drugs for myelofibrosis. Expert Opin Emerg Drugs 2012 0.77
20 Efficacy of ruxolitinib for myelofibrosis. Expert Opin Pharmacother 2014 0.77
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