Candida in the Respiratory Tract Secretions of Critically Ill Patients and The Efficacy of Antifungal Treatment (CANTREAT)

Clinical Trial ID NCT00934934

PubWeight™ 4.30‹?›

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Ventilator-associated pneumonia. Am J Respir Crit Care Med 2002 9.63
2 A randomized trial of diagnostic techniques for ventilator-associated pneumonia. N Engl J Med 2006 5.74
3 Beta-D-glucan as a diagnostic adjunct for invasive fungal infections: validation, cutoff development, and performance in patients with acute myelogenous leukemia and myelodysplastic syndrome. Clin Infect Dis 2004 4.15
4 Clinical and economic consequences of ventilator-associated pneumonia: a systematic review. Crit Care Med 2005 4.03
5 1,3-Beta-D-glucan antigenemia for early diagnosis of invasive fungal infections in neutropenic patients with acute leukemia. Clin Infect Dis 2008 3.19
6 Candida in the respiratory tract secretions of critically ill patients and the impact of antifungal treatment: a randomized placebo controlled pilot trial (CANTREAT study). Intensive Care Med 2014 2.70
7 A drug-sensitive genetic network masks fungi from the immune system. PLoS Pathog 2006 2.65
8 The design and interpretation of pilot trials in clinical research in critical care. Crit Care Med 2009 2.38
9 Comprehensive evidence-based clinical practice guidelines for ventilator-associated pneumonia: prevention. J Crit Care 2008 2.23
10 Randomized trial of combination versus monotherapy for the empiric treatment of suspected ventilator-associated pneumonia. Crit Care Med 2008 1.94
11 The clinical significance of Candida colonization of respiratory tract secretions in critically ill patients. J Crit Care 2008 1.67
12 Significance of the isolation of Candida species from respiratory samples in critically ill, non-neutropenic patients. An immediate postmortem histologic study. Am J Respir Crit Care Med 1997 1.63
13 Candida colonization of the respiratory tract and subsequent pseudomonas ventilator-associated pneumonia. Chest 2006 1.57
14 The association between anatomic site of Candida colonization, invasive candidiasis, and mortality in critically ill surgical patients. Diagn Microbiol Infect Dis 2006 1.54
15 The importance of pilot studies. Nurs Stand 2002 1.47
16 Impact of antifungal treatment on Candida-Pseudomonas interaction: a preliminary retrospective case-control study. Intensive Care Med 2006 1.45
17 Coincidence of pro- and anti-inflammatory responses in the early phase of severe sepsis: Longitudinal study of mononuclear histocompatibility leukocyte antigen-DR expression, procalcitonin, C-reactive protein, and changes in T-cell subsets in septic and postoperative patients. Crit Care Med 2002 1.25
18 Comprehensive evidence-based clinical practice guidelines for ventilator-associated pneumonia: diagnosis and treatment. J Crit Care 2008 1.21
19 The impact of ventilator-associated pneumonia on the Canadian health care system. J Crit Care 2008 1.10
20 The role of Candida sp isolated from bronchoscopic samples in nonneutropenic patients. Chest 1998 1.00
21 Candida albicans triggers activation of distinct signaling pathways to establish a proinflammatory gene expression program in primary human endothelial cells. J Immunol 2007 1.00
22 The relationship between Candida species cultured from the respiratory tract and systemic inflammation in critically ill patients with ventilator-associated pneumonia. Can J Anaesth 2010 0.83
23 Could procalcitonin be a predictive biological marker in systemic fungal infections?. Study of 14 cases. Eur J Intern Med 2002 0.82
24 Candida soluble cell wall beta-D-glucan induces lung inflammation in mice. Int J Immunopathol Pharmacol 2007 0.82
25 The clinical research enterprise in critical care: what's right, what's wrong, and what's ahead? Crit Care Med 2009 0.82
26 Cytokines in sepsis due to Candida albicans and in bacterial sepsis. Eur Cytokine Netw 1999 0.81
27 Impact of Candida species on clinical outcomes in patients with suspected ventilator-associated pneumonia. Can Respir J 2011 0.79
28 Effects of fungal beta-glucan and interferon-gamma on the secretory functions of murine alveolar macrophages. J Leukoc Biol 1996 0.78
29 Determinants of outcome in patients with a clinical suspicion of ventilator-associated pneumonia. J Crit Care 2008 0.78
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