CANVAS - CANagliflozin cardioVascular Assessment Study (CANVAS)

Clinical Trial ID NCT01032629

PubWeight™ 38.20‹?›

🔗 Visit the ClinicalTrials.gov page for NCT01032629

Top papers

Rank Title Journal Year PubWeight™‹?›
1 SGLT2 inhibition--a novel strategy for diabetes treatment. Nat Rev Drug Discov 2010 4.22
2 Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes. N Engl J Med 2017 4.18
3 Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future. Lancet 2013 2.66
4 Rationale, design, and baseline characteristics of the Canagliflozin Cardiovascular Assessment Study (CANVAS)--a randomized placebo-controlled trial. Am Heart J 2013 2.12
5 SGLT-2 inhibitors and cardiovascular risk: proposed pathways and review of ongoing outcome trials. Diab Vasc Dis Res 2015 1.73
6 Efficacy and safety of canagliflozin, an inhibitor of sodium-glucose cotransporter 2, when used in conjunction with insulin therapy in patients with type 2 diabetes. Diabetes Care 2014 1.52
7 The kidney in type 2 diabetes therapy. Rev Diabet Stud 2011 1.50
8 Update on developments with SGLT2 inhibitors in the management of type 2 diabetes. Drug Des Devel Ther 2014 1.14
9 A Novel Therapeutic Agent for Type 2 Diabetes Mellitus: SGLT2 Inhibitor. Diabetes Metab J 2014 1.14
10 Rationale, design, and baseline characteristics of a randomized, placebo-controlled cardiovascular outcome trial of empagliflozin (EMPA-REG OUTCOME™). Cardiovasc Diabetol 2014 1.12
11 Importance of cardiovascular disease risk management in patients with type 2 diabetes mellitus. Diabetes Metab Syndr Obes 2014 1.05
12 Effects of Canagliflozin on Fracture Risk in Patients With Type 2 Diabetes Mellitus. J Clin Endocrinol Metab 2015 1.03
13 Genital mycotic infections with canagliflozin, a sodium glucose co-transporter 2 inhibitor, in patients with type 2 diabetes mellitus: a pooled analysis of clinical studies. Curr Med Res Opin 2014 1.03
14 Effect of canagliflozin on serum electrolytes in patients with type 2 diabetes in relation to estimated glomerular filtration rate (eGFR). Curr Med Res Opin 2014 1.01
15 SGLT2 Inhibition and cardiovascular events: why did EMPA-REG Outcomes surprise and what were the likely mechanisms? Diabetologia 2016 0.98
16 Efficacy and safety of dapagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor, in diabetes mellitus. Cardiovasc Diabetol 2015 0.98
17 Sodium Glucose Co-transporter Type 2 (SGLT2) Inhibitors: Targeting the Kidney to Improve Glycemic Control in Diabetes Mellitus. Diabetes Ther 2013 0.98
18 Efficacy, safety and regulatory status of SGLT2 inhibitors: focus on canagliflozin. Nutr Diabetes 2014 0.91
19 Efficacy and Safety of Canagliflozin Used in Conjunction with Sulfonylurea in Patients with Type 2 Diabetes Mellitus: A Randomized, Controlled Trial. Diabetes Ther 2015 0.86
20 Canagliflozin Treatment in Patients with Type 2 Diabetes Mellitus. Clin Med Insights Endocrinol Diabetes 2015 0.85
21 The efficacy and safety of canagliflozin across racial groups in patients with type 2 diabetes mellitus. Curr Med Res Opin 2015 0.85
22 Clinical Update: Cardiovascular Disease in Diabetes Mellitus: Atherosclerotic Cardiovascular Disease and Heart Failure in Type 2 Diabetes Mellitus - Mechanisms, Management, and Clinical Considerations. Circulation 2016 0.84
23 Sodium-glucose co-transporter 2 (SGLT2) inhibitors: a growing class of antidiabetic agents. Drugs Context 2014 0.79
24 Current perspectives on cardiovascular outcome trials in diabetes. Cardiovasc Diabetol 2016 0.79
25 Canagliflozin: A Novel SGLT2 Inhibitor for Type 2 Diabetes Mellitus. N Am J Med Sci 2014 0.78
26 Novel drugs and intervention strategies for the treatment of chronic kidney disease. Br J Clin Pharmacol 2013 0.78
27 Simultaneous Reduction in Both HbA1c and Body Weight with Canagliflozin Versus Glimepiride in Patients with Type 2 Diabetes on Metformin. Diabetes Ther 2016 0.78
28 Canagliflozin-current status in the treatment of type 2 diabetes mellitus with focus on clinical trial data. World J Diabetes 2014 0.76
29 Impact of sodium-glucose cotransporter 2 inhibitors on blood pressure. Vasc Health Risk Manag 2016 0.75
30 Canagliflozin and fracture risk in individuals with type 2 diabetes: results from the CANVAS Program. Diabetologia 2019 0.75
31 Stress Cardiac Biomarkers, Cardiovascular and Renal Outcomes, and Response to Canagliflozin. J Am Coll Cardiol 2022 0.75
32 Cardiovascular Risk in Diabetes Mellitus: Complication of the Disease or of Antihyperglycemic Medications. Clin Pharmacol Ther 2015 0.75
33 Effects of Baseline Blood Pressure and Low-Density Lipoprotein Cholesterol on Safety and Efficacy of Canagliflozin in Japanese Patients with Type 2 Diabetes Mellitus. Adv Ther 2015 0.75
34 Glucose-lowering therapy in type 2 diabetes. New hope after the EMPA-REG outcome trial. Herz 2016 0.75
35 Cardiovascular effects of anti-diabetes drugs. Expert Opin Drug Saf 2016 0.75
36 Diabetes Drugs and Cardiovascular Safety. Endocrinol Metab (Seoul) 2016 0.75
37 Blood pressure and cardiovascular effects of new and emerging antidiabetic agents. Curr Hypertens Rep 2014 0.75
38 Closing the knowledge gap on cardiovascular disease in type 2 diabetes: the EMPA-REG OUTCOME trial and beyond. Drugs Context 2016 0.75
39 Canagliflozin: Efficacy and Safety in Combination with Metformin Alone or with Other Antihyperglycemic Agents in Type 2 Diabetes. Diabetes Ther 2016 0.75
Next 100