Safety and Efficacy of Sodium Nitrite in Sickle Cell Disease

Clinical Trial ID NCT01033227

PubWeight™ 1.13‹?›

🔗 Visit the ClinicalTrials.gov page for NCT01033227

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation. Nat Med 2003 8.95
2 Glucose-6-phosphate dehydrogenase deficiency. Lancet 2008 8.26
3 Lactate dehydrogenase as a biomarker of hemolysis-associated nitric oxide resistance, priapism, leg ulceration, pulmonary hypertension, and death in patients with sickle cell disease. Blood 2005 3.98
4 Platelet activation in patients with sickle disease, hemolysis-associated pulmonary hypertension, and nitric oxide scavenging by cell-free hemoglobin. Blood 2007 2.31
5 Nitrate and nitrite in biology, nutrition and therapeutics. Nat Chem Biol 2009 2.29
6 The biochemistry of nitric oxide, nitrite, and hemoglobin: role in blood flow regulation. Free Radic Biol Med 2004 2.12
7 Nitric oxide synthase reduces nitrite to NO under anoxia. Cell Mol Life Sci 2007 1.73
8 Sickle cell disease vasculopathy: a state of nitric oxide resistance. Free Radic Biol Med 2008 1.69
9 Nitric oxide's reactions with hemoglobin: a view through the SNO-storm. Nat Med 2003 1.61
10 Inorganic nitrite therapy: historical perspective and future directions. Free Radic Biol Med 2011 1.13
11 Sodium nitrite promotes regional blood flow in patients with sickle cell disease: a phase I/II study. Br J Haematol 2008 1.03
12 Assessment of cerebral tissue oxygenation in patients with sickle cell disease: effect of transfusion therapy. J Pediatr Hematol Oncol 2004 0.94
13 Near-infrared spectroscopy provides an index of blood flow and vasoconstriction in calf skeletal muscle during lower body negative pressure. Acta Physiol (Oxf) 2007 0.88
14 The acute chest syndrome in sickle cell disease. Possible role of nitric oxide in its pathophysiology and treatment. Am J Respir Crit Care Med 1999 0.88
15 Kinetics of estimated human muscle capillary blood flow during recovery from exercise. Exp Physiol 2005 0.82
16 Nitrite reduction to nitric oxide in the vasculature. Am J Physiol Heart Circ Physiol 2008 0.80
Next 100