Effects of Sildenafil on CFTR-dependent Ion Transport Activity

Clinical Trial ID NCT01132482

PubWeight™ 0.77‹?›

🔗 Visit the ClinicalTrials.gov page for NCT01132482

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Preclinical evidence that sildenafil and vardenafil activate chloride transport in cystic fibrosis. Am J Respir Crit Care Med 2007 2.18
2 Structural analog of sildenafil identified as a novel corrector of the F508del-CFTR trafficking defect. Mol Pharmacol 2007 1.25
3 Sildenafil (Viagra) corrects DeltaF508-CFTR location in nasal epithelial cells from patients with cystic fibrosis. Thorax 2005 0.98
4 Pharmacological modulation of cGMP levels by phosphodiesterase 5 inhibitors as a therapeutic strategy for treatment of respiratory pathology in cystic fibrosis. Am J Physiol Lung Cell Mol Physiol 2007 0.86
5 Endosomal hyperacidification in cystic fibrosis is due to defective nitric oxide-cylic GMP signalling cascade. EMBO Rep 2006 0.86
6 Pharmacokinetics and tolerability of oral sildenafil in adults with cystic fibrosis lung disease. J Cyst Fibros 2014 0.77
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