The Addition of Temozolomide to Conditioning for Autologous Transplantation in Relapsed & Refractory Central Nervous System (CNS) Lymphoma (DRBEAT)

Clinical Trial ID NCT01235793

PubWeight™ 1.33‹?›

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 2005 74.55
2 CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma. N Engl J Med 2002 19.60
3 Autologous bone marrow transplantation as compared with salvage chemotherapy in relapses of chemotherapy-sensitive non-Hodgkin's lymphoma. N Engl J Med 1995 9.72
4 Cancer phase I clinical trials: efficient dose escalation with overdose control. Stat Med 1998 4.19
5 Report of an international workshop to standardize baseline evaluation and response criteria for primary CNS lymphoma. J Clin Oncol 2005 3.47
6 Chemoradiotherapy in malignant glioma: standard of care and future directions. J Clin Oncol 2007 2.93
7 Phase I study of intraventricular administration of rituximab in patients with recurrent CNS and intraocular lymphoma. J Clin Oncol 2007 2.64
8 Salvage therapy for primary CNS lymphoma with a combination of rituximab and temozolomide. Neurology 2004 2.41
9 Treatment of primary CNS lymphoma with methotrexate and deferred radiotherapy: a report of NABTT 96-07. J Clin Oncol 2003 2.30
10 Immunochemotherapy with rituximab and temozolomide for central nervous system lymphomas. Cancer 2004 2.00
11 Plasma and cerebrospinal fluid population pharmacokinetics of temozolomide in malignant glioma patients. Clin Cancer Res 2004 1.95
12 Temozolomide as salvage treatment in primary brain lymphomas. Br J Cancer 2007 1.81
13 Intensive chemotherapy followed by hematopoietic stem-cell rescue for refractory and recurrent primary CNS and intraocular lymphoma: Société Française de Greffe de Moëlle Osseuse-Thérapie Cellulaire. J Clin Oncol 2008 1.65
14 Diagnosis and treatment of primary CNS lymphoma. Nat Rev Neurol 2013 1.56
15 Flexible Bayesian methods for cancer phase I clinical trials. Dose escalation with overdose control. Stat Med 2005 1.50
16 Results of intensive chemotherapy followed by hematopoietic stem-cell rescue in 22 patients with refractory or recurrent primary CNS lymphoma or intraocular lymphoma. J Clin Oncol 2001 1.47
17 Primary CNS lymphoma in immunocompetent patients. Oncologist 2009 1.41
18 Intensive methotrexate and cytarabine followed by high-dose chemotherapy with autologous stem-cell rescue in patients with newly diagnosed primary CNS lymphoma: an intent-to-treat analysis. J Clin Oncol 2003 1.41
19 Treatment of relapsed central nervous system lymphoma with high-dose methotrexate. Clin Cancer Res 2004 1.30
20 BEAM chemotherapy and autologous bone marrow transplantation for patients with relapsed or refractory non-Hodgkin's lymphoma. J Clin Oncol 1995 1.29
21 Phase I trial of temozolomide (NSC 362856) in patients with advanced cancer. Clin Cancer Res 1997 1.19
22 Patient specific dosing in a cancer phase I clinical trial. Stat Med 2001 1.16
23 Plasma and cerebrospinal fluid pharmacokinetics of intravenous temozolomide in non-human primates. J Neurooncol 2003 1.11
24 Autologous peripheral blood stem cell transplantation for acute myelogenous leukemia. Bone Marrow Transplant 1997 1.10
25 Temozolomide, a novel alkylating agent with activity in the central nervous system, may improve the treatment of advanced metastatic melanoma. Oncologist 2000 1.09
26 Salvage stereotactic radiosurgery effectively treats recurrences from whole-brain radiation therapy. Cancer 2008 1.06
27 Etoposide achieves potentially cytotoxic concentrations in CSF of children with acute lymphoblastic leukemia. J Clin Oncol 1996 1.00
28 Effect of dose and schedule on pharmacokinetics of high-dose cytosine arabinoside in plasma and cerebrospinal fluid. J Clin Oncol 1983 0.99
29 Phase 2 study of BCNU and temozolomide for recurrent glioblastoma multiforme: North American Brain Tumor Consortium study. Neuro Oncol 2004 0.99
30 High-dose chemotherapy with autologous stem cell transplantation as first-line therapy for primary CNS lymphoma in patients younger than 60 years: a multicenter phase II study of the GOELAMS group. Bone Marrow Transplant 2006 0.99
31 Alteration of the pharmacokinetics of high-dose ara-C by its metabolite, high ara-U in patients with acute leukemia. J Clin Oncol 1983 0.96
32 Dose-dense regimen of temozolomide given every other week in patients with primary central nervous system tumors. Ann Oncol 2004 0.93
33 Temozolomide in patients with advanced cancer: phase I and pharmacokinetic study. Pharmacotherapy 2004 0.93
34 Pharmacodynamics of tandem high-dose melphalan with peripheral blood stem cell transplantation in children with neuroblastoma and medulloblastoma. Bone Marrow Transplant 2001 0.91
35 Topotecan as salvage therapy for relapsed or refractory primary central nervous system lymphoma. J Neurooncol 2007 0.89
36 High-dose thiotepa, busulfan, cyclophosphamide and ASCT without whole-brain radiotherapy for poor prognosis primary CNS lymphoma. Bone Marrow Transplant 2003 0.86
37 The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of diffuse large cell B-cell non-Hodgkin's lymphoma: an evidence-based review. Biol Blood Marrow Transplant 2001 0.84
38 Intensive chemotherapy with high doses of BCNU, etoposide, cytosine arabinoside, and melphalan (BEAM) followed by autologous bone marrow transplantation: toxicity and antitumor activity in 26 patients with poor-risk malignancies. Cancer Chemother Pharmacol 1988 0.82
39 Use of temozolomide with other cytotoxic chemotherapy in the treatment of patients with recurrent brain metastases from lung cancer. Oncologist 2003 0.82
40 L-phenylalanine mustard (melphalan) uptake and cross-linking in the RPMI 6410 human lymphoblastoid cell line. Cancer Res 1980 0.80
41 Clinical presentation, diagnosis, and pharmacotherapy of patients with primary brain tumors. Ann Pharmacother 1999 0.80
42 Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy. Neuro Oncol 2004 0.79
43 Neoplastic meningitis from breast cancer: feasibility and activity of long-term intrathecal liposomal Ara-C combined with dose-dense temozolomide. Anticancer Res 2009 0.78
44 Autologous stem cell transplantation with PCR-negative graft would be associated with a favorable outcome in core-binding factor acute myeloid leukemia. Biol Blood Marrow Transplant 2008 0.78
45 Phase I study of temozolomide and escalating doses of oral etoposide for adults with recurrent malignant glioma. Cancer 2003 0.78
46 Intrathecal liposomal cytarabine in combination with temozolomide in low-grade oligoastrocytoma with leptomeningeal dissemination. J Neurooncol 2009 0.77
47 Primary central nervous system lymphomas: salvage treatment after failure to high-dose methotrexate. Cancer Lett 2007 0.77
48 Radiotherapy at tumor recurrence in primary CNS lymphoma. Neurology 1998 0.75
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