PubRank

Effect of Sulforaphane in Broccoli Sprouts on Nrf2 Activation

Clinical Trial ID NCT01315665

PubWeight™ 0.75‹?›

🔗 Visit the ClinicalTrials.gov page for NCT01315665

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Effect of high-dose ibuprofen in patients with cystic fibrosis. N Engl J Med 1995 4.82
2 Cystic fibrosis pulmonary guidelines: chronic medications for maintenance of lung health. Am J Respir Crit Care Med 2007 4.34
3 Extremely potent triterpenoid inducers of the phase 2 response: correlations of protection against oxidant and inflammatory stress. Proc Natl Acad Sci U S A 2005 3.08
4 Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes. Mol Cancer Ther 2007 2.71
5 The synthetic triterpenoids, CDDO and CDDO-imidazolide, are potent inducers of heme oxygenase-1 and Nrf2/ARE signaling. Cancer Res 2005 2.67
6 A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells. Clin Cancer Res 2006 1.92
7 Triterpenoid CDDO-Me blocks the NF-kappaB pathway by direct inhibition of IKKbeta on Cys-179. J Biol Chem 2006 1.92
8 The role of inflammation in the pathophysiology of CF lung disease. Clin Rev Allergy Immunol 2002 1.85
9 Clinical use of Ibuprofen is associated with slower FEV1 decline in children with cystic fibrosis. Am J Respir Crit Care Med 2007 1.75
10 Inflammation and anti-inflammatory therapies for cystic fibrosis. Clin Chest Med 2007 1.29
11 The use of anti-inflammatory medications in cystic fibrosis: trends and physician attitudes. Chest 1999 1.23
12 Dysfunction of Nrf-2 in CF epithelia leads to excess intracellular H2O2 and inflammatory cytokine production. PLoS One 2008 1.08
13 Signaling intermediates required for NF-kappa B activation and IL-8 expression in CF bronchial epithelial cells. Am J Physiol Lung Cell Mol Physiol 2002 1.07
14 Effect of ibuprofen on neutrophil migration in vivo in cystic fibrosis and healthy subjects. J Pharmacol Exp Ther 2003 1.04
15 Role of IKK and ERK pathways in intrinsic inflammation of cystic fibrosis airways. Biochem Pharmacol 2007 1.02
16 The triterpenoid CDDO limits inflammation in preclinical models of cystic fibrosis lung disease. Am J Physiol Lung Cell Mol Physiol 2009 0.97
17 Ibuprofen therapy for cystic fibrosis lung disease: revisited. Curr Opin Pulm Med 2008 0.94
18 Oral non-steroidal anti-inflammatory drug therapy for cystic fibrosis. Cochrane Database Syst Rev 2007 0.84
19 Fluticasone reduces IL-6 and IL-8 production of cystic fibrosis bronchial epithelial cells via IKK-beta kinase pathway. Eur Respir J 2003 0.84
20 Chemical and biological mechanisms of phytochemical activation of Nrf2 and importance in disease prevention. Recent Adv Phytochem 2013 0.75
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