Inhaled Xylitol Versus Saline in Stable Subjects With Cystic Fibrosis

Clinical Trial ID NCT01355796

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Top papers

Rank	Title	Journal	Year	PubWeight™‹?›
1	Cystic fibrosis.	N Engl J Med	2005	8.09
2	Human beta-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis.	Cell	1997	5.99
3	Production of beta-defensins by human airway epithelia.	Proc Natl Acad Sci U S A	1998	3.85
4	Human beta-defensin 2 is a salt-sensitive peptide antibiotic expressed in human lung.	J Clin Invest	1998	3.51
5	Loss of CFTR chloride channels alters salt absorption by cystic fibrosis airway epithelia in vitro.	Mol Cell	1998	2.31
6	Activity of abundant antimicrobials of the human airway.	Am J Respir Cell Mol Biol	1999	1.93
7	Xylitol chewing gums and caries rates: a 40-month cohort study.	J Dent Res	1995	1.78
8	Xylitol chewing gum in prevention of acute otitis media: double blind randomised trial.	BMJ	1996	1.52
9	The osmolyte xylitol reduces the salt concentration of airway surface liquid and may enhance bacterial killing.	Proc Natl Acad Sci U S A	2000	1.00
10	Effect of sorbitol, xylitol, and xylitol/sorbitol chewing gums on dental plaque.	Caries Res	1989	0.92
11	Safety assessment of inhaled xylitol in mice and healthy volunteers.	Respir Res	2004	0.86
12	Long-term tolerance of healthy human subjects to high amounts of xylitol and fructose: general and biochemical findings.	Int Z Vitam Ernahrungsforsch Beih	1976	0.78
13	Pulmonary function and sputum production in patients with cystic fibrosis: a pilot study comparing the PercussiveTech HF device and standard chest physiotherapy.	Chest	2004	0.77
14	Bronchoscopic assessment of airway retention time of aerosolized xylitol.	Respir Res	2006	0.77
15	Safety assessment of inhaled xylitol in subjects with cystic fibrosis.	J Cyst Fibros	2006	0.75