PubRank

Nitric Oxide Bioavailability in Chronic Obstructive Pulmonary Disease (COPD)

Clinical Trial ID NCT01398943

PubWeight™ 0.00‹?›

🔗 Visit the ClinicalTrials.gov page for NCT01398943

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med 1997 14.51
2 Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis. Lancet 1992 11.50
3 Point: Flow-mediated dilation does reflect nitric oxide-mediated endothelial function. J Appl Physiol (1985) 2005 9.97
4 The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta. Nature 1998 6.69
5 Nitric oxide synthases in mammals. Biochem J 1994 6.50
6 Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease. Circulation 2000 6.13
7 Differences in interleukin-8 and tumor necrosis factor-alpha in induced sputum from patients with chronic obstructive pulmonary disease or asthma. Am J Respir Crit Care Med 1996 5.53
8 Long-term follow-up of patients with mild coronary artery disease and endothelial dysfunction. Circulation 2000 5.53
9 Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor. Am J Physiol 1986 4.88
10 Cigarette smoking is associated with dose-related and potentially reversible impairment of endothelium-dependent dilation in healthy young adults. Circulation 1993 4.53
11 Hospitalizations and mortality in the Lung Health Study. Am J Respir Crit Care Med 2002 4.11
12 Passive smoking and impaired endothelium-dependent arterial dilatation in healthy young adults. N Engl J Med 1996 3.59
13 Tetrahydrobiopterin augments endothelium-dependent dilatation in sedentary but not in habitually exercising older adults. J Physiol 2005 2.86
14 Use of salsalate to target inflammation in the treatment of insulin resistance and type 2 diabetes. Clin Transl Sci 2008 2.54
15 Effect of a single high-fat meal on endothelial function in healthy subjects. Am J Cardiol 1997 2.53
16 Tetrahydrobiopterin improves endothelium-dependent vasodilation in chronic smokers : evidence for a dysfunctional nitric oxide synthase. Circ Res 2000 2.52
17 Endothelial function testing as a biomarker of vascular disease. Circulation 2003 2.30
18 NF-kappa B and I kappa B alpha: an inducible regulatory system in endothelial activation. J Exp Med 1994 2.10
19 Flow-induced vasodilation of the human brachial artery is impaired in patients <40 years of age with coronary artery disease. Am J Cardiol 1996 2.09
20 Heterogenous nature of flow-mediated dilatation in human conduit arteries in vivo: relevance to endothelial dysfunction in hypercholesterolemia. Circ Res 2001 2.02
21 Determinants of systemic vascular function in patients with stable chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2008 2.02
22 Effect of antioxidant vitamins on the transient impairment of endothelium-dependent brachial artery vasoactivity following a single high-fat meal. JAMA 1997 1.99
23 Nuclear factor-{kappa}B activation contributes to vascular endothelial dysfunction via oxidative stress in overweight/obese middle-aged and older humans. Circulation 2009 1.99
24 Impaired flow-mediated dilation is associated with low pulmonary function and emphysema in ex-smokers: the Emphysema and Cancer Action Project (EMCAP) Study. Am J Respir Crit Care Med 2007 1.90
25 Free radicals and antioxidants: a personal view. Nutr Rev 1994 1.76
26 Pivotal role for endothelial tetrahydrobiopterin in pulmonary hypertension. Circulation 2005 1.62
27 Matrix metalloproteinases. Matrix degradation and more. Am J Respir Cell Mol Biol 1999 1.57
28 Exercise and the nitric oxide vasodilator system. Sports Med 2003 1.48
29 Pulmonary hypertension in a GTP-cyclohydrolase 1-deficient mouse. Circulation 2005 1.38
30 Supplementation with vitamins C and E improves arterial stiffness and endothelial function in essential hypertensive patients. Am J Hypertens 2007 1.36
31 Pathogenesis of chronic obstructive pulmonary disease. Clin Chest Med 2007 1.34
32 Tetrahydrobiopterin: regulator of endothelial nitric oxide synthase in vascular disease. Trends Cardiovasc Med 2004 1.34
33 Pathophysiological implications of insulin resistance on vascular endothelial function. Diabet Med 2003 1.33
34 A large blood pressure-raising effect of nitric oxide synthase inhibition in humans. Hypertension 1999 1.33
35 Noninvasive assessment of endothelium-dependent flow-mediated dilation of the brachial artery. Vasc Med 1997 1.26
36 Tetrahydrobiopterin restores endothelial function in long-term smokers. J Am Coll Cardiol 2000 1.23
37 Effects of oxidative stress on endothelial function after a high-fat meal. Clin Sci (Lond) 2004 1.20
38 The effect of acute exercise on endothelial function following a high-fat meal. Eur J Appl Physiol 2006 1.14
39 Arterial endothelial dysfunction related to passive smoking is potentially reversible in healthy young adults. Ann Intern Med 1999 1.13
40 EPR spectroscopic detection of free radical outflow from an isolated muscle bed in exercising humans. J Appl Physiol (1985) 2003 1.09
41 The effect of oral antioxidants on brachial artery flow-mediated dilation following 5 and 10 min of ischemia. Eur J Appl Physiol 2009 1.09
42 Effect of exercise training on endothelial function in men with coronary artery disease. Am J Cardiol 2004 1.07
43 Chronic obstructive pulmonary disease as a predictor of mortality in patients undergoing percutaneous coronary intervention. Am J Cardiol 2005 1.06
44 Nitric oxide synthase inhibition reduces glucose uptake during exercise in individuals with type 2 diabetes more than in control subjects. Diabetes 2002 1.04
45 Effect of folic acid and antioxidant vitamins on endothelial dysfunction in patients with coronary artery disease. J Am Coll Cardiol 2000 1.01
46 Effects of cyclosporine A on skeletal muscle mitochondrial respiration and endurance time in rats. Am J Respir Crit Care Med 1995 1.00
47 Variability of flow-mediated dilation measurements with repetitive reactive hyperemia. Vasc Med 2006 0.95
48 Cytokines and therapy in COPD: a promising combination? Chest 2002 0.92
49 Preserved contribution of nitric oxide to baseline vascular tone in deconditioned human skeletal muscle. J Physiol 2005 0.89
50 Endothelial dysfunction in chronic obstructive pulmonary disease. Angiology 2008 0.89
51 Endothelial dysfunction and type 2 diabetes. Part 1: physiology and methods for exploring the endothelial function. Diabetes Metab 2001 0.89
52 A comparison between active- and reactive-hyperaemia-induced brachial artery vasodilation. Clin Sci (Lond) 2006 0.88
53 Additional benefit of vitamin E supplementation to simvastatin therapy on vasoreactivity of the brachial artery of hypercholesterolemic men. J Am Coll Cardiol 1998 0.86
54 Endothelial GTPCH in eNOS uncoupling and atherosclerosis. Arterioscler Thromb Vasc Biol 2007 0.86
55 Metabolic and vascular limb differences affected by exercise, gender, age, and disease. Med Sci Sports Exerc 2006 0.85
56 Reproducibility of the flow-mediated dilation response to acute exercise in overweight men. Ultrasound Med Biol 2007 0.83
57 Assessment of salsalate, a nonacetylated salicylate, in the treatment of patients with arthritis. Clin Ther 1996 0.82
58 Salsalate, a nonacetylated salicylate, is as efficacious as diclofenac in patients with rheumatoid arthritis. Salsalate-Diclofenac Study Group. J Rheumatol 1995 0.79
59 Skeletal muscle function in COPD. Chest 2000 0.78
60 [The role of endothelial dysfunction in the pathogenesis of combined cardiopulmonary diseases]. Klin Med (Mosk) 2006 0.75
61 Exercise capacity after combined heart-lung transplantation. Transplant Proc 1992 0.75
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