Effect of PBT2 in Patients With Early to Mid Stage Huntington Disease (Reach2HD)

Clinical Trial ID NCT01590888

PubWeight™ 3.06‹?›

🔗 Visit the ClinicalTrials.gov page for NCT01590888

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial. Lancet Neurol 2008 3.03
2 PBT2 rapidly improves cognition in Alzheimer's Disease: additional phase II analyses. J Alzheimers Dis 2010 1.57
3 Safety, tolerability, and efficacy of PBT2 in Huntington's disease: a phase 2, randomised, double-blind, placebo-controlled trial. Lancet Neurol 2014 1.46
4 The iron regulatory capability of the major protein participants in prevalent neurodegenerative disorders. Front Pharmacol 2014 0.91
5 PBT2 Reduces Toxicity in a C. elegans Model of polyQ Aggregation and Extends Lifespan, Reduces Striatal Atrophy and Improves Motor Performance in the R6/2 Mouse Model of Huntington's Disease. J Huntingtons Dis 2012 0.79
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