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The Effects of Ketamine and Guanfacine on Working Memory in Healthy Subjects (GuaKet)
Clinical Trial ID NCT01600885
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🔗 Visit the ClinicalTrials.gov page for NCT01600885
Top papers
Rank
Title
Journal
Year
PubWeight™
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1
The assessment and analysis of handedness: the Edinburgh inventory.
Neuropsychologia
1971
86.03
2
Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia.
Arch Gen Psychiatry
2000
6.91
3
Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia.
Nat Med
2006
4.00
4
Alpha2A-adrenoceptors strengthen working memory networks by inhibiting cAMP-HCN channel signaling in prefrontal cortex.
Cell
2007
3.60
5
Magical ideation as an indicator of schizotypy.
J Consult Clin Psychol
1983
2.65
6
Body-image aberration in Schizophrenia.
J Abnorm Psychol
1978
2.29
7
Neuregulin1 (NRG1) signaling through Fyn modulates NMDA receptor phosphorylation: differential synaptic function in NRG1+/- knock-outs compared with wild-type mice.
J Neurosci
2007
1.94
8
An open trial of guanfacine in the treatment of attention-deficit hyperactivity disorder.
J Am Acad Child Adolesc Psychiatry
1995
1.81
9
Impairment of working memory maintenance and response in schizophrenia: functional magnetic resonance imaging evidence.
Biol Psychiatry
2008
1.76
10
Sustained mnemonic response in the human middle frontal gyrus during on-line storage of spatial memoranda.
J Cogn Neurosci
2002
1.63
11
Guanfacine treatment of cognitive impairment in schizophrenia.
Neuropsychopharmacology
2001
1.61
12
Comparative and interactive human psychopharmacologic effects of ketamine and amphetamine: implications for glutamatergic and dopaminergic model psychoses and cognitive function.
Arch Gen Psychiatry
2005
1.52
13
DISC1 immunoreactivity at the light and ultrastructural level in the human neocortex.
J Comp Neurol
2006
1.42
14
Guanfacine, but not clonidine, improves planning and working memory performance in humans.
Neuropsychopharmacology
1999
1.23
15
Locomotor hyperactivity induced by blockade of prefrontal cortical alpha2-adrenoceptors in monkeys.
Biol Psychiatry
2005
1.05
16
Association of the adrenergic alpha2A receptor gene with methylphenidate improvement of inattentive symptoms in children and adolescents with attention-deficit/hyperactivity disorder.
Arch Gen Psychiatry
2007
1.04
17
Dendritic spine density in schizophrenia and depression.
Arch Gen Psychiatry
2001
1.00
18
Complex haplotypes derived from noncoding polymorphisms of the intronless alpha2A-adrenergic gene diversify receptor expression.
Proc Natl Acad Sci U S A
2006
0.95
19
The effects of guanfacine on context processing abnormalities in schizotypal personality disorder.
Biol Psychiatry
2006
0.95
20
Imidazoline antihypertensive drugs: a critical review on their mechanism of action.
Pharmacol Ther
2002
0.94
21
How has DISC1 enabled drug discovery?
Mol Cell Neurosci
2007
0.94
22
Postsynaptic alpha-2 receptor stimulation improves memory in aged monkeys: indirect effects of yohimbine versus direct effects of clonidine.
Neurobiol Aging
1994
0.91
23
Adrenergic alpha2A receptor gene and response to methylphenidate in attention-deficit/hyperactivity disorder-predominantly inattentive type.
J Neural Transm (Vienna)
2008
0.91
24
The effects of an alpha-2 adrenergic agonist, guanfacine, on rCBF in human cortex in normal controls and subjects with focal epilepsy.
Neuropsychopharmacology
2000
0.83
25
Absence of behavioral sensitization in healthy human subjects following repeated exposure to ketamine.
Psychopharmacology (Berl)
2005
0.82
26
Neuropharmacologic and behavioral actions of clonidine: interactions with central neurotransmitters.
Int Rev Neurobiol
1992
0.81
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