Erythromycin Treatment for Readthrough of APC Gene Stop Codon Mutation in Familial Adenomatous Polyposis-minors' Adjusted Version

Clinical Trial ID NCT02354560

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene. Hum Mol Genet 1992 5.14
2 Gentamicin-induced correction of CFTR function in patients with cystic fibrosis and CFTR stop mutations. N Engl J Med 2003 4.43
3 Effectiveness of PTC124 treatment of cystic fibrosis caused by nonsense mutations: a prospective phase II trial. Lancet 2008 4.35
4 Hereditary and familial colon cancer. Gastroenterology 2010 4.15
5 The APC gene product in normal and tumor cells. Proc Natl Acad Sci U S A 1993 3.25
6 Eicosapentaenoic acid reduces rectal polyp number and size in familial adenomatous polyposis. Gut 2010 2.23
7 Correction of ATM gene function by aminoglycoside-induced read-through of premature termination codons. Proc Natl Acad Sci U S A 2004 1.64
8 The role of APC and beta-catenin in the aetiology of aggressive fibromatosis (desmoid tumors). Eur J Surg Oncol 2008 1.35
9 Evaluation of management of desmoid tumours associated with familial adenomatous polyposis in Dutch patients. Br J Cancer 2010 1.24
10 Restoration of APC gene function in colorectal cancer cells by aminoglycoside- and macrolide-induced read-through of premature termination codons. Gut 2009 1.01
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