PubRank

Plasma Cytochrome c as Biomarker of Traumatic Injury and Predictor of Outcome

Clinical Trial ID NCT02440373

PubWeight™ 0.00‹?›

🔗 Visit the ClinicalTrials.gov page for NCT02440373

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Med 1996 35.00
2 Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997 24.57
3 Multiple organ dysfunction score: a reliable descriptor of a complex clinical outcome. Crit Care Med 1995 10.29
4 Biochemical pathways of caspase activation during apoptosis. Annu Rev Cell Dev Biol 1999 8.21
5 An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9. J Biol Chem 1999 6.88
6 Emergency medical services intervals and survival in trauma: assessment of the "golden hour" in a North American prospective cohort. Ann Emerg Med 2009 3.92
7 A descriptive analysis of Emergency Medical Service Systems participating in the Resuscitation Outcomes Consortium (ROC) network. Prehosp Emerg Care 2007 3.90
8 Cytochrome c release from mitochondria proceeds by a two-step process. Proc Natl Acad Sci U S A 2002 3.57
9 Cytochrome c: functions beyond respiration. Nat Rev Mol Cell Biol 2008 2.95
10 Out-of-hospital hypertonic resuscitation after traumatic hypovolemic shock: a randomized, placebo controlled trial. Ann Surg 2011 2.85
11 Epidemiology and outcomes from out-of-hospital cardiac arrest in children: the Resuscitation Outcomes Consortium Epistry-Cardiac Arrest. Circulation 2009 2.49
12 Comparison of multiple organ dysfunction scores in the prediction of hospital mortality in the critically ill. Crit Care Med 2002 2.47
13 Apoptosis in heart failure: release of cytochrome c from mitochondria and activation of caspase-3 in human cardiomyopathy. Proc Natl Acad Sci U S A 1999 2.42
14 The design and interpretation of pilot trials in clinical research in critical care. Crit Care Med 2009 2.38
15 Functional consequences of caspase activation in cardiac myocytes. Proc Natl Acad Sci U S A 2002 1.98
16 Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation. J Biol Chem 1999 1.96
17 Multiple organ dysfunction: baseline and serial component scores. Crit Care Med 2001 1.88
18 Signaling pathways in reactive oxygen species-induced cardiomyocyte apoptosis. Circulation 1999 1.74
19 Impact of prehospital mode of transport after severe injury: a multicenter evaluation from the Resuscitation Outcomes Consortium. J Trauma Acute Care Surg 2012 1.71
20 The Multiple Organ Dysfunction Score (MODS) versus the Sequential Organ Failure Assessment (SOFA) score in outcome prediction. Intensive Care Med 2002 1.71
21 Multiple organ failure in trauma patients. J Trauma 2003 1.66
22 Zoniporide preserves left ventricular compliance during ventricular fibrillation and minimizes postresuscitation myocardial dysfunction through benefits on energy metabolism. Crit Care Med 2007 1.66
23 The Multiple Organ Dysfunction Score as a descriptor of patient outcome in septic shock compared with two other scoring systems. Crit Care Med 1999 1.50
24 Mitochondrial oxidant stress triggers cell death in simulated ischemia-reperfusion. Biochim Biophys Acta 2010 1.35
25 Circulating levels of cytochrome c after resuscitation from cardiac arrest: a marker of mitochondrial injury and predictor of survival. Am J Physiol Heart Circ Physiol 2006 1.22
26 Cytochrome c: occurrence and functions. Chem Rev 2006 1.21
27 Serum cytochrome c indicates in vivo apoptosis and can serve as a prognostic marker during cancer therapy. Int J Cancer 2005 1.17
28 Ca2+-induced reactive oxygen species production promotes cytochrome c release from rat liver mitochondria via mitochondrial permeability transition (MPT)-dependent and MPT-independent mechanisms: role of cardiolipin. J Biol Chem 2004 1.15
29 Cytochrome c and tumor necrosis factor-alpha values in serum and cerebrospinal fluid of patients with influenza-associated encephalopathy. Pediatr Infect Dis J 2005 1.11
30 Caspase activation and mitochondrial cytochrome C release during hypoxia-mediated apoptosis of adult ventricular myocytes. J Mol Cell Cardiol 2000 1.09
31 Cytochrome c biogenesis in mitochondria. Mitochondrion 2007 1.06
32 Apoptosis and the systolic dysfunction in congestive heart failure. Story of apoptosis interruptus and zombie myocytes. Cardiol Clin 2001 0.98
33 Treatment of uncontrolled hemorrhagic shock after liver trauma: fatal effects of fluid resuscitation versus improved outcome after vasopressin. Anesth Analg 2004 0.95
34 Serum cytochrome c level as a prognostic indicator in patients with systemic inflammatory response syndrome. Clin Chim Acta 2004 0.94
35 Mechanism of the cardioprotection of rhEPO pretreatment on suppressing the inflammatory response in ischemia-reperfusion. Life Sci 2005 0.93
36 Prognostic predictive values of serum cytochrome c, cytokines, and other laboratory measurements in acute encephalopathy with multiple organ failure. Arch Dis Child 2006 0.93
37 Evidence for early supply independent mitochondrial dysfunction in patients developing multiple organ failure after trauma. J Trauma 1997 0.92
38 Proximal tubular cytochrome c efflux: determinant, and potential marker, of mitochondrial injury. Kidney Int 2004 0.91
39 Arginine vasopressin: the future of pressure-support resuscitation in hemorrhagic shock. J Surg Res 2012 0.89
40 Steady as a ROC: the Resuscitation Outcomes Consortium. Resuscitation 2008 0.88
41 Vasopressin for hemorrhagic shock management: revisiting the potential value in civilian and combat casualty care. J Trauma 2010 0.86
42 Protecting mitochondrial bioenergetic function during resuscitation from cardiac arrest. Crit Care Clin 2012 0.85
43 Cytochrome c is a possible new marker for fulminant hepatitis in humans. J Gastroenterol 2005 0.84
44 Circulating cytochrome c as potential biomarker of impaired reperfusion in ST-segment elevation acute myocardial infarction. Am J Cardiol 2010 0.83
45 Cytochrome-c detection: a diagnostic marker for myocardial infarction. Appl Biochem Biotechnol 2001 0.82
46 AVE4454B--a novel sodium-hydrogen exchanger isoform-1 inhibitor--compared less effective than cariporide for resuscitation from cardiac arrest. Transl Res 2010 0.80
47 Cytochrome c is rapidly extruded from apoptotic cells and detectable in serum of anticancer-drug treated tumor patients. Adv Exp Med Biol 2001 0.79
48 Activation of caspase-3 may not contribute to postresuscitation myocardial dysfunction. Am J Physiol Heart Circ Physiol 2009 0.78
49 Serum cytochrome c to indicate the extent of ongoing tumor cell death. Int J Lab Hematol 2008 0.77
50 Serum cytochrome c detection using a cytochrome c oxidase biosensor. Biotechnol Appl Biochem 2007 0.75
51 Determination of cytochrome c in human serum and pharmaceutical injections using flow injection chemiluminescence. Appl Biochem Biotechnol 2009 0.75
52 Disposable biosensor based on Au nanoparticles-modified CdS nanorod arrays for detection cytochrome c. J Nanosci Nanotechnol 2011 0.75
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