Assessing the Efficacy and Safety of Metformin in Treatment of Moderate Psoriasis

Clinical Trial ID NCT02644954

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Risk of myocardial infarction in patients with psoriasis. JAMA 2006 9.42
2 Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin. Circulation 2000 6.96
3 Cellular and molecular mechanisms of metformin: an overview. Clin Sci (Lond) 2012 4.04
4 European S3-guidelines on the systemic treatment of psoriasis vulgaris. J Eur Acad Dermatol Venereol 2009 3.56
5 Association between disease-modifying antirheumatic drugs and diabetes risk in patients with rheumatoid arthritis and psoriasis. JAMA 2011 3.02
6 Prevalence of metabolic syndrome in patients with psoriasis: a hospital-based case-control study. Br J Dermatol 2007 2.40
7 Psoriasis: a possible risk factor for development of coronary artery calcification. Br J Dermatol 2007 1.86
8 Interleukin-12, interleukin-23, and psoriasis: current prospects. J Am Acad Dermatol 2007 1.76
9 The concept of psoriasis as a systemic inflammation: implications for disease management. J Eur Acad Dermatol Venereol 2012 1.06
10 Metformin and liraglutide ameliorate high glucose-induced oxidative stress via inhibition of PKC-NAD(P)H oxidase pathway in human aortic endothelial cells. Atherosclerosis 2013 1.04
11 Inflammation in atherosclerosis and psoriasis: common pathogenic mechanisms and the potential for an integrated treatment approach. Br J Dermatol 2008 0.95
12 Effect of weight change and metformin on fibrinolysis and the von Willebrand factor in obese nondiabetic subjects: the BIGPRO1 Study. Biguanides and the Prevention of the Risk of Obesity. Diabetes Care 1998 0.90
13 Metformin ameliorates methotrexate-induced hepatotoxicity. J Pharmacol Pharmacother 2012 0.87
14 A marriage of two "Methusalem" drugs for the treatment of psoriasis?: Arguments for a pilot trial with metformin as add-on for methotrexate. Dermatoendocrinol 2013 0.85
15 Metformin inhibits proliferation of human keratinocytes through a mechanism associated with activation of the MAPK signaling pathway. Exp Ther Med 2013 0.80
16 Impact of metformin and rosiglitazone treatment on glucose transporter 4 mRNA expression in women with polycystic ovary syndrome. Eur J Endocrinol 2008 0.78
17 Effects of metformin on the glycemic control, lipid profile, and arterial blood pressure of type 2 diabetic patients with metabolic syndrome already on insulin. Braz J Med Biol Res 2006 0.77
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