Effects of Ranibizumab to Delay or Regression Non-proliferative Diabetic Retinopathy(NPDR) With DME Assessed by Microaneurysm Changes: A Pilot Study

Clinical Trial ID NCT02834663

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer. Nat Rev Drug Discov 2004 9.96
2 Vascular endothelial growth factor and angiogenesis. Pharmacol Rev 2004 5.41
3 Photocoagulation treatment of proliferative diabetic retinopathy. Clinical application of Diabetic Retinopathy Study (DRS) findings, DRS Report Number 8. The Diabetic Retinopathy Study Research Group. Ophthalmology 1981 4.72
4 Diabetic retinopathy and angiogenesis. Curr Diabetes Rev 2009 1.92
5 Pericytes and the pathogenesis of diabetic retinopathy. Horm Metab Res 2005 1.74
6 Aqueous humour levels of cytokines are correlated to vitreous levels and severity of macular oedema in branch retinal vein occlusion. Eye (Lond) 2006 1.73
7 VEGF164(165) as the pathological isoform: differential leukocyte and endothelial responses through VEGFR1 and VEGFR2. Invest Ophthalmol Vis Sci 2004 1.45
8 Microaneurysms in the development of diabetic retinopathy (UKPDS 42). UK Prospective Diabetes Study Group. Diabetologia 1999 1.38
9 Histological and ultrastructural investigation of retinal microaneurysm development in diabetic patients. Br J Ophthalmol 1995 1.25
10 Optical coherence tomographic characteristics of microaneurysms in diabetic retinopathy. Am J Ophthalmol 2010 1.15
11 Microaneurysm turnover is a biomarker for diabetic retinopathy progression to clinically significant macular edema: findings for type 2 diabetics with nonproliferative retinopathy. Ophthalmologica 2009 1.13
12 Does microaneurysm count reflect severity of early diabetic retinopathy? Ophthalmology 1986 1.02
13 Microaneurysm turnover at the macula predicts risk of development of clinically significant macular edema in persons with mild nonproliferative diabetic retinopathy. Diabetes Care 2012 0.99
14 Retinal microaneurysm count predicts progression and regression of diabetic retinopathy. Post-hoc results from the DIRECT Programme. Diabet Med 2011 0.98
15 Vascular basement membrane thickening in diabetic retinopathy. Curr Eye Res 2010 0.97
16 Microaneurysm formation rate as a predictive marker for progression to clinically significant macular edema in nonproliferative diabetic retinopathy. Retina 2014 0.95
17 Effects of bevacizumab on the neovascular membrane of proliferative diabetic retinopathy: reduction of endothelial cells and expressions of VEGF and HIF-1α. Mol Vis 2012 0.83
18 Microaneurysm turnover in diabetic retinopathy assessed by automated RetmarkerDR image analysis--potential role as biomarker of response to ranibizumab treatment. Ophthalmologica 2014 0.77
19 High vitreous concentration of vascular endothelial growth factor in diabetic patients with proliferative retinopathy using statins. Ann Med 2008 0.75
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