Ambroxol as a Treatment for Parkinson's Disease Dementia

Clinical Trial ID NCT02914366

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Glucocerebrosidase deficiency in substantia nigra of parkinson disease brains. Ann Neurol 2012 2.20
2 Challenges in Parkinson's disease: restoration of the nigrostriatal dopamine system is not enough. Lancet Neurol 2004 2.11
3 Pilot study using ambroxol as a pharmacological chaperone in type 1 Gaucher disease. Blood Cells Mol Dis 2012 1.58
4 Augmenting CNS glucocerebrosidase activity as a therapeutic strategy for parkinsonism and other Gaucher-related synucleinopathies. Proc Natl Acad Sci U S A 2013 1.45
5 Identification and characterization of ambroxol as an enzyme enhancement agent for Gaucher disease. J Biol Chem 2009 1.39
6 Lysosomal hydrolases in cerebrospinal fluid from subjects with Parkinson's disease. Mov Disord 2007 1.13
7 Ambroxol in the 21st century: pharmacological and clinical update. Expert Opin Drug Metab Toxicol 2008 0.92
8 The chaperone activity and toxicity of ambroxol on Gaucher cells and normal mice. Brain Dev 2012 0.91
9 An alternative to steroids for prevention of respiratory distress syndrome (RDS): multicenter controlled study to compare ambroxol and betamethasone. J Perinat Med 1987 0.82
10 Antenatal use of ambroxol for the prevention of infant respiratory distress syndrome. J Obstet Gynaecol Res 2000 0.81
11 Changes in pulmonary function in preterm infants recovering from RDS following early treatment with ambroxol: results of a randomized trial. Pediatr Pulmonol 1999 0.81
12 Ambroxol for prevention and treatment of hyaline membrane disease. Eur Respir J Suppl 1989 0.77
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