Intrathecal Tetanus Immunoglobulin to Treat Tetanus (ITITTT)

Clinical Trial ID NCT02999815

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Intrathecal antitetanus serum (horse) in the treatment of tetanus. Lancet 1977 2.39
2 Device-associated nosocomial infections in 55 intensive care units of 8 developing countries. Ann Intern Med 2006 2.20
3 Magnesium sulphate for treatment of severe tetanus: a randomised controlled trial. Lancet 2006 1.81
4 More on influenza vaccine in young children. N Engl J Med 2012 1.57
5 Intrathecal tetanus immunoglobulins in the management of tetanus. Indian J Pediatr 2007 1.54
6 The need for a journal policy on intrathecal, epidural, and perineural administration of non-approved drugs. Pain 2010 1.42
7 Intrathecal immunoglobulin in the treatment of tetanus. Indian Pediatr 2002 1.39
8 Analysis of retrograde transport in motor neurons reveals common endocytic carriers for tetanus toxin and neurotrophin receptor p75NTR. J Cell Biol 2002 1.38
9 Maternal and neonatal tetanus. Lancet 2014 1.38
10 Management of tetanus: a review of 18 cases. J R Soc Med 1994 1.19
11 Impact of improved vaccination programme and intensive care facilities on incidence and outcome of tetanus in southern Vietnam, 1993-2002. Trans R Soc Trop Med Hyg 2004 1.11
12 Brain damage after neonatal tetanus in a rural Kenyan hospital. Trop Med Int Health 2001 1.10
13 Randomised controlled trial of tetanus treatment with antitetanus immunoglobulin by the intrathecal or intramuscular route. BMJ 2004 1.06
14 Double-blind trial of equine antitoxin and human immune globulin in tetanus neonatorum. Lancet 1971 1.06
15 Intrathecal human tetanus immunoglobulin in early tetanus. Lancet 1980 1.01
16 Brain bioavailability of human intravenous immunoglobulin and its transport through the murine blood-brain barrier. J Cereb Blood Flow Metab 2013 1.01
17 Pharmacological management of tetanus: an evidence-based review. Crit Care 2014 0.97
18 Intrathecal therapy in tetanus. A meta-analysis. JAMA 1991 0.93
19 Intrathecal vs. intramuscular administration of human antitetanus immunoglobulin or equine tetanus antitoxin in the treatment of tetanus: a meta-analysis. Trop Med Int Health 2006 0.93
20 Predicting the clinical outcome of tetanus: the tetanus severity score. Trop Med Int Health 2006 0.92
21 Neuronal activity-dependent membrane traffic at the neuromuscular junction. Proc Natl Acad Sci U S A 2002 0.91
22 Therapeutic trial of intracisternal human tetanus immunoglobulin in clinical tetanus. Trans R Soc Trop Med Hyg 1979 0.88
23 Semi-recumbent body position fails to prevent healthcare-associated pneumonia in Vietnamese patients with severe tetanus. Trans R Soc Trop Med Hyg 2011 0.87
24 A new treatment for neonatal tetanus. Antitetanic serum and prednisolone given together intrathecally. Turk J Pediatr 1967 0.87
25 A randomized double-blind sham-controlled study of intrathecal human anti-tetanus immunoglobulin in the management of tetanus. Natl Med J India 2000 0.85
26 [Reversible paraplegia following intrathecal injection of high doses of human gammaglobulins in the treatment of low-grade tetanus. 4 cases]. Presse Med 1984 0.84
27 Intracerebral antitoxin in experimental tetanus. Br J Exp Pathol 1966 0.83
28 Intrathecal serotherapy of tetanus. I. Explanation of complications. II. Comparison of intrathecal tetanus immune globulin and tetanus antitoxin. Turk J Pediatr 1974 0.82
29 Pathogenesis of local tetanus in the dog and the cat. J Immunol 1949 0.81
30 Effect of intrathecal glycine and related amino acids on the allodynia and hyperalgesic action of strychnine or bicuculline in mice. Korean J Anesthesiol 2010 0.79
31 Fragment C of tetanus toxin: new insights into its neuronal signaling pathway. Int J Mol Sci 2012 0.79
32 Intrathecal anti-tetanus human immunoglobulin in the treatment of neonatal tetanus. J Coll Physicians Surg Pak 2011 0.78
33 Rapid, sensitive, and specific detection of Clostridium tetani by loop-mediated isothermal amplification assay. J Microbiol Biotechnol 2013 0.77
34 Intrathecal glycine for pain and dystonia in complex regional pain syndrome. Pain 2009 0.77
35 Long-term survival after intensive care unit discharge in Thailand: a retrospective study. Crit Care 2013 0.76
36 [Intrathecal therapy with 1 500 UI of antitetanic serum and 1.5 g of intravenous metronidazole: prognosis of tetanus in hospitalized patients in Togo]. Sante 2009 0.75
37 Failure of intrathecal antitetanus serum to improve survival in neonatal tetanus. Arch Dis Child 1983 0.75
38 Pharmacology of intracisternal or intrathecal glycine, muscimol, and baclofen in strychnine-induced thermal hyperalgesia of mice. J Korean Med Sci 2011 0.75
39 Human serum sickness. Clin Rev Allergy 1985 0.75
40 Tetanus neonatorum--experience with intrathecal serotherapy at Muhimbili Medical Centre, Dar es Salaam, Tanzania. Ann Trop Paediatr 1987 0.75
41 Intrathecal serotherapy in neonatal tetanus: a controlled trial. Arch Dis Child 1979 0.75
42 The therapeutic effect of homologous and heterologous antitoxins in experimental diphtheria and tetanus. Br J Exp Pathol 1970 0.75
43 Current practice in the management of tetanus. Crit Care 2014 0.75
44 Tetanus; the use of human hyperimmune globulin in treatment. Calif Med 1963 0.75
45 An immunohistochemical study on a tetanus fatal case using toxin fragment C (TTC). Should it be a useful diagnostic tool? Neuropathology 2008 0.75
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