PubRank

Early Goal Directed Therapy Using a Physiological Holistic View. The ANDROMEDA-SHOCK Study (ANDROMEDA)

Clinical Trial ID NCT03078712

PubWeight™ 0.00‹?›

🔗 Visit the ClinicalTrials.gov page for NCT03078712

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012. Intensive Care Med 2013 17.37
2 Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial. JAMA 2010 8.09
3 Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial. Am J Respir Crit Care Med 2010 5.41
4 Circulatory shock. N Engl J Med 2013 4.95
5 The effects of dobutamine on microcirculatory alterations in patients with septic shock are independent of its systemic effects. Crit Care Med 2006 3.53
6 Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine. Intensive Care Med 2014 3.37
7 The effect of increasing doses of norepinephrine on tissue oxygenation and microvascular flow in patients with septic shock. Crit Care Med 2009 2.60
8 Increasing arterial blood pressure with norepinephrine does not improve microcirculatory blood flow: a prospective study. Crit Care 2009 2.32
9 Central venous-to-arterial carbon dioxide difference: an additional target for goal-directed therapy in septic shock? Intensive Care Med 2008 2.14
10 Can venous-to-arterial carbon dioxide differences reflect microcirculatory alterations in patients with septic shock? Intensive Care Med 2015 1.59
11 Re-thinking resuscitation: leaving blood pressure cosmetics behind and moving forward to permissive hypotension and a tissue perfusion-based approach. Crit Care 2013 1.50
12 Persistent sepsis-induced hypotension without hyperlactatemia: is it really septic shock? J Crit Care 2010 1.34
13 Microvascular flow and tissue oxygenation after major abdominal surgery: association with post-operative complications. Intensive Care Med 2008 1.26
14 Fluid overload, de-resuscitation, and outcomes in critically ill or injured patients: a systematic review with suggestions for clinical practice. Anaesthesiol Intensive Ther 2014 1.20
15 Sepsis-associated hyperlactatemia. Crit Care 2014 1.17
16 Iatrogenic salt water drowning and the hazards of a high central venous pressure. Ann Intensive Care 2014 1.13
17 Effects of dobutamine on systemic, regional and microcirculatory perfusion parameters in septic shock: a randomized, placebo-controlled, double-blind, crossover study. Intensive Care Med 2013 1.09
18 Persistently high venous-to-arterial carbon dioxide differences during early resuscitation are associated with poor outcomes in septic shock. Crit Care 2013 1.09
19 Persistent Sepsis-Induced Hypotension without Hyperlactatemia: A Distinct Clinical and Physiological Profile within the Spectrum of Septic Shock. Crit Care Res Pract 2012 1.01
20 The holistic view on perfusion monitoring in septic shock. Curr Opin Crit Care 2012 0.99
21 Severe abnormalities in microvascular perfused vessel density are associated to organ dysfunctions and mortality and can be predicted by hyperlactatemia and norepinephrine requirements in septic shock patients. J Crit Care 2013 0.99
22 Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion. Crit Care 2015 0.99
23 Combination of arterial lactate levels and venous-arterial CO2 to arterial-venous O 2 content difference ratio as markers of resuscitation in patients with septic shock. Intensive Care Med 2015 0.96
24 When to stop septic shock resuscitation: clues from a dynamic perfusion monitoring. Ann Intensive Care 2014 0.96
25 Early lactate clearance-guided therapy in patients with sepsis: a meta-analysis with trial sequential analysis of randomized controlled trials. Intensive Care Med 2015 0.91
26 Adaptive Designs for Clinical Trials. N Engl J Med 2016 0.90
27 Evolution of peripheral vs metabolic perfusion parameters during septic shock resuscitation. A clinical-physiologic study. J Crit Care 2011 0.89
28 Lactate-guided resuscitation saves lives: we are not sure. Intensive Care Med 2016 0.88
29 Relationship of systemic, hepatosplanchnic, and microcirculatory perfusion parameters with 6-hour lactate clearance in hyperdynamic septic shock patients: an acute, clinical-physiological, pilot study. Ann Intensive Care 2012 0.88
30 Early peripheral perfusion-guided fluid therapy in patients with septic shock. Am J Respir Crit Care Med 2015 0.87
31 Effects of dexmedetomidine and esmolol on systemic hemodynamics and exogenous lactate clearance in early experimental septic shock. Crit Care 2016 0.83
32 Understanding clinical signs of poor tissue perfusion during septic shock. Intensive Care Med 2016 0.82
33 Nitroglycerin reverts clinical manifestations of poor peripheral perfusion in patients with circulatory shock. Crit Care 2014 0.80
34 Changes in peripheral perfusion relate to visceral organ perfusion in early septic shock: A pilot study. J Crit Care 2016 0.79
35 Clinical assessment of peripheral circulation. Curr Opin Crit Care 2015 0.77
36 [Prevalence of severe sepsis in intensive care units. A national multicentric study]. Rev Med Chil 2007 0.76
37 Is the macrocirculation really dissociated from the microcirculation in septic shock? Intensive Care Med 2016 0.75
Next 100