Effects of the Addition of Metyrapone to Antidepressant Therapy in Depression With Dexamethasone Suppression Test Non-suppression.

Clinical Trial ID NCT03491696

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Epigenetic programming by maternal behavior. Nat Neurosci 2004 20.92
2 Remission rates during treatment with venlafaxine or selective serotonin reuptake inhibitors. Br J Psychiatry 2001 4.33
3 Glucocorticoid receptors in major depression: relevance to pathophysiology and treatment. Biol Psychiatry 2001 3.39
4 Mood disorders and allostatic load. Biol Psychiatry 2003 3.23
5 A specific laboratory test for the diagnosis of melancholia. Standardization, validation, and clinical utility. Arch Gen Psychiatry 1981 2.76
6 Depression and hypothalamic-pituitary-adrenal activation: a quantitative summary of four decades of research. Psychosom Med 2011 2.30
7 The DST as a predictor of outcome in depression: a meta-analysis. Am J Psychiatry 1993 1.95
8 Do corticosteroids damage the brain? J Neuroendocrinol 2006 1.64
9 Metyrapone as additive treatment in major depression: a double-blind and placebo-controlled trial. Arch Gen Psychiatry 2004 1.63
10 Antidepressant augmentation with metyrapone for treatment-resistant depression (the ADD study): a double-blind, randomised, placebo-controlled trial. Lancet Psychiatry 2015 1.42
11 Not fade away: the HPA axis and depression. Psychol Med 2010 0.99
12 Antiglucocorticoid treatments for mood disorders. Cochrane Database Syst Rev 2008 0.96
13 Pharmacological modulation of HPA axis in depression - new avenues for potential therapeutic benefits. Psychiatr Danub 2013 0.82
14 Neuroendocrine profiles in mood disorders. Int J Neuropsychopharmacol 2003 0.82
15 Effect of metyrapone supplementation on imipramine therapy in patients with treatment-resistant unipolar depression. Pol J Pharmacol 2005 0.79
16 Neuroendocrine responses to inhibitors of steroid biosynthesis in patients with major depression resistant to antidepressant therapy. Can J Psychiatry 1998 0.76
17 Relationship between chronobiological thyrotropin and prolactin responses to protirelin (TRH) and suicidal behavior in depressed patients. Psychoneuroendocrinology 2017 0.75
18 Genomic and epigenomic mechanisms of glucocorticoids in the brain. Nat Rev Endocrinol 2017 0.75
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