Study of Daratumumab in Multiple Myeloma (MM) Patients in >VGPR/MRD-positive (DART4MM)

Clinical Trial ID NCT03992170

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987 174.79
2 Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma. N Engl J Med 2008 13.06
3 Improved survival in multiple myeloma and the impact of novel therapies. Blood 2007 12.70
4 Melphalan and prednisone plus thalidomide versus melphalan and prednisone alone or reduced-intensity autologous stem cell transplantation in elderly patients with multiple myeloma (IFM 99-06): a randomised trial. Lancet 2007 7.23
5 Multiple myeloma. Blood 2008 5.88
6 Bortezomib with thalidomide plus dexamethasone compared with thalidomide plus dexamethasone as induction therapy before, and consolidation therapy after, double autologous stem-cell transplantation in newly diagnosed multiple myeloma: a randomised phase 3 study. Lancet 2010 5.59
7 Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: randomised controlled trial. Lancet 2006 5.07
8 Clinical and biologic implications of recurrent genomic aberrations in myeloma. Blood 2003 4.67
9 Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma. Blood 2010 4.52
10 Recent major improvement in long-term survival of younger patients with multiple myeloma. Blood 2007 4.08
11 Bortezomib plus dexamethasone is superior to vincristine plus doxorubicin plus dexamethasone as induction treatment prior to autologous stem-cell transplantation in newly diagnosed multiple myeloma: results of the IFM 2005-01 phase III trial. J Clin Oncol 2010 4.02
12 Bortezomib induction and maintenance treatment in patients with newly diagnosed multiple myeloma: results of the randomized phase III HOVON-65/ GMMG-HD4 trial. J Clin Oncol 2012 3.93
13 A phase 1/2 study of carfilzomib in combination with lenalidomide and low-dose dexamethasone as a frontline treatment for multiple myeloma. Blood 2012 3.44
14 Efficacy and safety of once-weekly bortezomib in multiple myeloma patients. Blood 2010 2.84
15 Oral melphalan, prednisone, and thalidomide in elderly patients with multiple myeloma: updated results of a randomized controlled trial. Blood 2008 2.68
16 Efficacy of melphalan and prednisone plus thalidomide in patients older than 75 years with newly diagnosed multiple myeloma: IFM 01/01 trial. J Clin Oncol 2009 2.49
17 Superiority of bortezomib, thalidomide, and dexamethasone (VTD) as induction pretransplantation therapy in multiple myeloma: a randomized phase 3 PETHEMA/GEM study. Blood 2012 2.42
18 Complete response correlates with long-term progression-free and overall survival in elderly myeloma treated with novel agents: analysis of 1175 patients. Blood 2011 2.37
19 Melphalan and prednisone plus thalidomide or placebo in elderly patients with multiple myeloma. Blood 2010 2.33
20 Daratumumab, Bortezomib, and Dexamethasone for Multiple Myeloma. N Engl J Med 2016 2.32
21 Major tumor shrinking and persistent molecular remissions after consolidation with bortezomib, thalidomide, and dexamethasone in patients with autografted myeloma. J Clin Oncol 2010 2.25
22 Randomized, multicenter, phase 2 study (EVOLUTION) of combinations of bortezomib, dexamethasone, cyclophosphamide, and lenalidomide in previously untreated multiple myeloma. Blood 2012 2.07
23 New drugs and novel mechanisms of action in multiple myeloma in 2013: a report from the International Myeloma Working Group (IMWG). Leukemia 2013 2.04
24 Phase III study of the value of thalidomide added to melphalan plus prednisone in elderly patients with newly diagnosed multiple myeloma: the HOVON 49 Study. J Clin Oncol 2010 1.81
25 Once- versus twice-weekly bortezomib induction therapy with CyBorD in newly diagnosed multiple myeloma. Blood 2010 1.79
26 Thalidomide for previously untreated elderly patients with multiple myeloma: meta-analysis of 1685 individual patient data from 6 randomized clinical trials. Blood 2011 1.69
27 Current trends in autologous stem-cell transplantation for myeloma in the era of novel therapies. J Clin Oncol 2011 1.60
28 How I treat multiple myeloma in younger patients. Blood 2009 1.48
29 Cyclophosphamide, thalidomide, and dexamethasone (CTD) as initial therapy for patients with multiple myeloma unsuitable for autologous transplantation. Blood 2011 1.32
30 Addition of thalidomide to oral melphalan/prednisone in patients with multiple myeloma not eligible for transplantation: results of a randomized trial from the Turkish Myeloma Study Group. Eur J Haematol 2010 1.30
31 Extramedullary intracranial localization of multiple myeloma and treatment with novel agents: a retrospective survey of 50 patients. Cancer 2011 1.18
32 Fluorescence in situ hybridization: uses and limitations. Semin Hematol 2000 1.16
33 Phase 2 study of carfilzomib, thalidomide, and dexamethasone as induction/consolidation therapy for newly diagnosed multiple myeloma. Blood 2014 0.89
34 Initial treatment of nontransplant patients with multiple myeloma. Semin Oncol 2013 0.78
35 Daratumumab plus Bortezomib, Melphalan, and Prednisone for Untreated Myeloma. N Engl J Med 2017 0.75
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