A Phase III Study Comparing Efficacy, Safety and Tolerability of the Fixed Dose Triple Combination CHF 5993 With the Fixed Dose Dual Combination CHF 1535 in Subjects With COPD (TRITON)

Clinical Trial ID NCT04320342

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012 56.72
2 Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med 2006 49.95
3 Standardisation of spirometry. Eur Respir J 2005 48.20
4 Effect of exacerbation on quality of life in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1998 10.05
5 Usefulness of the Medical Research Council (MRC) dyspnoea scale as a measure of disability in patients with chronic obstructive pulmonary disease. Thorax 1999 8.63
6 Antibiotic therapy in exacerbations of chronic obstructive pulmonary disease. Ann Intern Med 1987 8.41
7 Development and first validation of the COPD Assessment Test. Eur Respir J 2009 8.06
8 Hepatic encephalopathy--definition, nomenclature, diagnosis, and quantification: final report of the working party at the 11th World Congresses of Gastroenterology, Vienna, 1998. Hepatology 2002 7.53
9 Multi-ethnic reference values for spirometry for the 3-95-yr age range: the global lung function 2012 equations. Eur Respir J 2012 7.18
10 Chronic obstructive pulmonary disease: current burden and future projections. Eur Respir J 2006 6.34
11 St. George's Respiratory Questionnaire: MCID. COPD 2005 3.99
12 Efficacy and tolerability of budesonide/formoterol added to tiotropium in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2009 3.61
13 Minimum clinically important difference for the COPD Assessment Test: a prospective analysis. Lancet Respir Med 2014 2.69
14 Single inhaler triple therapy versus inhaled corticosteroid plus long-acting β2-agonist therapy for chronic obstructive pulmonary disease (TRILOGY): a double-blind, parallel group, randomised controlled trial. Lancet 2016 2.19
15 Review article: the design of clinical trials in hepatic encephalopathy--an International Society for Hepatic Encephalopathy and Nitrogen Metabolism (ISHEN) consensus statement. Aliment Pharmacol Ther 2011 1.97
16 The local side effects of inhaled corticosteroids: current understanding and review of the literature. Chest 2004 1.76
17 Creating scenarios of the impact of COPD and their relationship to COPD Assessment Test (CAT™) scores. BMC Pulm Med 2011 1.54
18 Comparison of tiotropium plus fluticasone propionate/salmeterol with tiotropium in COPD: a randomized controlled study. Respir Med 2011 1.14
19 Measuring the effects of COPD on the patient. Respir Med 2005 1.13
20 Benefits of adding fluticasone propionate/salmeterol to tiotropium in moderate to severe COPD. Respir Med 2011 1.05
21 Extrafine beclomethasone/formoterol in severe COPD patients with history of exacerbations. Respir Med 2014 1.03
22 Inhalational and topical steroids, and oral candidosis: a mini review. Oral Dis 2001 0.95
23 Acute bronchodilator responsiveness in subjects with and without airflow obstruction in five Latin American cities: the PLATINO study. Pulm Pharmacol Ther 2009 0.82
24 FULFIL Trial: Once-Daily Triple Therapy in Patients with Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med 2017 0.80
25 Standardisation of lung function testing: the authors' replies to readers' comments. Eur Respir J 2010 0.77
26 Single inhaler extrafine triple therapy versus long-acting muscarinic antagonist therapy for chronic obstructive pulmonary disease (TRINITY): a double-blind, parallel group, randomised controlled trial. Lancet 2017 0.76
27 Responder Analyses for Treatment Effects in COPD Using the St George's Respiratory Questionnaire. Chronic Obstr Pulm Dis 2017 0.75
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