Study of Safety and Efficacy of MGCND00EP1 as an Add on Treatment in Children and Adolescents With Resistant Epilepsies

Clinical Trial ID NCT04406948

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 The Columbia-Suicide Severity Rating Scale: initial validity and internal consistency findings from three multisite studies with adolescents and adults. Am J Psychiatry 2011 9.18
2 The clinical global impressions scale: applying a research tool in clinical practice. Psychiatry (Edgmont) 2007 3.02
3 Systematic review: efficacy and safety of medical marijuana in selected neurologic disorders: report of the Guideline Development Subcommittee of the American Academy of Neurology. Neurology 2014 2.37
4 Herbal medicine in the United States: review of efficacy, safety, and regulation: grand rounds at University of California, San Francisco Medical Center. J Gen Intern Med 2008 2.08
5 Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial. Lancet Neurol 2015 2.07
6 Cannabidiol: pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders. Epilepsia 2014 1.97
7 Development of the quality of life in epilepsy inventory. Epilepsia 1995 1.93
8 Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug. Braz J Med Biol Res 2006 1.76
9 History of cannabis and its preparations in saga, science, and sobriquet. Chem Biodivers 2007 1.60
10 Report of a parent survey of cannabidiol-enriched cannabis use in pediatric treatment-resistant epilepsy. Epilepsy Behav 2013 1.50
11 Metabolism, disposition, and kinetics of delta-9-tetrahydrocannabinol in men and women. Clin Pharmacol Ther 1983 1.44
12 Plasma delta-9 tetrahydrocannabinol concentrations and clinical effects after oral and intravenous administration and smoking. Clin Pharmacol Ther 1980 1.43
13 Adverse health effects of marijuana use. N Engl J Med 2014 1.37
14 The case for medical marijuana in epilepsy. Epilepsia 2014 1.28
15 Parental reporting of response to oral cannabis extracts for treatment of refractory epilepsy. Epilepsy Behav 2015 1.13
16 Cannabidiol displays antiepileptiform and antiseizure properties in vitro and in vivo. J Pharmacol Exp Ther 2009 1.12
17 Drug-drug interaction between clobazam and cannabidiol in children with refractory epilepsy. Epilepsia 2015 1.07
18 Age at onset of epilepsy, pharmacoresistance, and cognitive outcomes: a prospective cohort study. Neurology 2012 1.06
19 Safety and side effects of cannabidiol, a Cannabis sativa constituent. Curr Drug Saf 2011 1.03
20 Cannabinoids for epilepsy. Cochrane Database Syst Rev 2012 1.01
21 The case for assessing cannabidiol in epilepsy. Epilepsia 2014 0.96
22 Letter: The effect of cannabidiol on maximal electroshock seizures in rats. J Pharm Pharmacol 1973 0.86
23 Cannabidiol as a new treatment for drug-resistant epilepsy in tuberous sclerosis complex. Epilepsia 2016 0.86
24 The Pharmacological Basis of Cannabis Therapy for Epilepsy. J Pharmacol Exp Ther 2016 0.85
25 Placebo and nocebo responses in drug trials of epilepsy. Epilepsy Behav 2015 0.85
26 CBD-enriched medical cannabis for intractable pediatric epilepsy: The current Israeli experience. Seizure 2016 0.84
27 Marijuana: an effective antiepileptic treatment in partial epilepsy? A case report and review of the literature. Rev Neurol Dis 2007 0.80
28 Opportunity gained, opportunity lost: treating pharmacoresistant epilepsy in children. Epilepsia 2013 0.78
29 Induction and genetic regulation of mouse hepatic cytochrome P450 by cannabidiol. Biochem Pharmacol 1994 0.77
30 Potential therapeutical effects of cannabidiol in children with pharmacoresistant epilepsy. Med Hypotheses 2006 0.77
31 Cannabinoids in paediatric neurology. Dev Med Child Neurol 2015 0.75
32 Options for pharmacoresistant epilepsy in children: when medications don't work. Pediatr Ann 2015 0.75
33 Investigational new drugs for focal epilepsy. Expert Opin Investig Drugs 2015 0.75
34 Development and assessment of a shortened Quality of Life in Childhood Epilepsy Questionnaire (QOLCE-55). Epilepsia 2015 0.75
35 Interaction of delta9-tetrahydrocannabinol and cannabidiol with phenobarbitone in protecting mice from electrically induced convulsions. J Pharm Pharmacol 1975 0.75
36 Validating the shortened Quality of Life in Childhood Epilepsy Questionnaire (QOLCE-55) in a sample of children with drug-resistant epilepsy. Epilepsia 2017 0.75
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