Primary Prevention of Infection by COVID-19 in Health Providers (PI-Covid-19)

Clinical Trial ID NCT04420260

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N Engl J Med 2012 22.75
2 Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020 18.32
3 Bats are natural reservoirs of SARS-like coronaviruses. Science 2005 13.44
4 Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China. Science 2003 12.59
5 A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature 2020 9.42
6 Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats. Proc Natl Acad Sci U S A 2005 8.52
7 A Novel Coronavirus from Patients with Pneumonia in China, 2019. N Engl J Med 2020 7.78
8 Oxidative stress, inflammation, and cancer: how are they linked? Free Radic Biol Med 2010 7.31
9 Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA 2020 6.59
10 Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC. Nature 2013 6.39
11 Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group. J Virol 2013 4.98
12 A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet 2020 3.90
13 Epidemiology and cause of severe acute respiratory syndrome (SARS) in Guangdong, People's Republic of China, in February, 2003. Lancet 2003 3.66
14 Close relative of human Middle East respiratory syndrome coronavirus in bat, South Africa. Emerg Infect Dis 2013 3.61
15 The pungency of garlic: activation of TRPA1 and TRPV1 in response to allicin. Curr Biol 2005 3.53
16 Middle East respiratory syndrome coronavirus infection in dromedary camels in Saudi Arabia. MBio 2014 3.49
17 Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human. Proc Natl Acad Sci U S A 2005 3.37
18 Novel coronavirus infections in Jordan, April 2012: epidemiological findings from a retrospective investigation. East Mediterr Health J 2013 2.42
19 Genetic characterization of Betacoronavirus lineage C viruses in bats reveals marked sequence divergence in the spike protein of pipistrellus bat coronavirus HKU5 in Japanese pipistrelle: implications for the origin of the novel Middle East respiratory syndrome coronavirus. J Virol 2013 1.67
20 Middle East respiratory syndrome coronavirus: another zoonotic betacoronavirus causing SARS-like disease. Clin Microbiol Rev 2015 1.64
21 Description and clinical treatment of an early outbreak of severe acute respiratory syndrome (SARS) in Guangzhou, PR China. J Med Microbiol 2003 1.58
22 Mechanism of NLRP3 inflammasome activation. Ann N Y Acad Sci 2014 1.54
23 Middle East respiratory syndrome coronavirus: a case-control study of hospitalized patients. Clin Infect Dis 2014 1.52
24 Pathological findings of COVID-19 associated with acute respiratory distress syndrome. Lancet Respir Med 2020 1.38
25 Angiotensin II and the endothelium: diverse signals and effects. Hypertension 2005 1.28
26 Inducible bronchus-associated lymphoid tissue elicited by a protein cage nanoparticle enhances protection in mice against diverse respiratory viruses. PLoS One 2009 1.23
27 Eugenol suppresses cyclooxygenase-2 expression in lipopolysaccharide-stimulated mouse macrophage RAW264.7 cells. Life Sci 2003 1.22
28 Middle East respiratory syndrome coronavirus infection mediated by the transmembrane serine protease TMPRSS2. J Virol 2013 1.21
29 Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike protein. Proc Natl Acad Sci U S A 2014 1.20
30 Echinacea-induced cytokine production by human macrophages. Int J Immunopharmacol 1997 1.13
31 Oxidative stress and inflammation: essential partners in alcoholic liver disease. Int J Hepatol 2012 1.05
32 Structure and inhibition of the SARS coronavirus envelope protein ion channel. PLoS Pathog 2009 1.04
33 Behaviorally Assessed Sleep and Susceptibility to the Common Cold. Sleep 2015 1.02
34 Vitamin D induces interleukin-1β expression: paracrine macrophage epithelial signaling controls M. tuberculosis infection. PLoS Pathog 2013 1.02
35 CXC chemokine ligand 9/monokine induced by IFN-gamma production by tumor cells is critical for T cell-mediated suppression of cutaneous tumors. J Immunol 2007 1.00
36 Inhibition of cell growth and induction of apoptosis via inactivation of NF-kappaB by a sulfurcompound isolated from garlic in human colon cancer cells. J Pharmacol Sci 2007 0.99
37 Investigation of antioxidant, anti-inflammatory and DNA-protective properties of eugenol in thioacetamide-induced liver injury in rats. Toxicology 2009 0.99
38 MERS-CoV papain-like protease has deISGylating and deubiquitinating activities. Virology 2013 0.99
39 Activity of and effect of subcutaneous treatment with the broad-spectrum antiviral lectin griffithsin in two laboratory rodent models. Antimicrob Agents Chemother 2013 0.97
40 Epidemiology, Genetic Recombination, and Pathogenesis of Coronaviruses. Trends Microbiol 2016 0.96
41 Rhesus theta-defensin prevents death in a mouse model of severe acute respiratory syndrome coronavirus pulmonary disease. J Virol 2009 0.96
42 Mechanism and Regulation of NLRP3 Inflammasome Activation. Trends Biochem Sci 2016 0.95
43 Targeting membrane-bound viral RNA synthesis reveals potent inhibition of diverse coronaviruses including the middle East respiratory syndrome virus. PLoS Pathog 2014 0.93
44 Specific plant terpenoids and lignoids possess potent antiviral activities against severe acute respiratory syndrome coronavirus. J Med Chem 2007 0.89
45 Innate immune response of human alveolar type II cells infected with severe acute respiratory syndrome-coronavirus. Am J Respir Cell Mol Biol 2013 0.88
46 Antioxidant action and therapeutic efficacy of Allium sativum L. Molecules 2013 0.88
47 Kava and St. John's Wort: current evidence for use in mood and anxiety disorders. J Altern Complement Med 2009 0.87
48 Fast-Track Zika Vaccine Development - Is It Possible? N Engl J Med 2016 0.86
49 Broad-spectrum antiviral therapeutics. PLoS One 2011 0.85
50 Allicin attenuates inflammation and suppresses HLA-B27 protein expression in ankylosing spondylitis mice. Biomed Res Int 2013 0.84
51 Middle East respiratory syndrome coronavirus (MERS-CoV) outbreak in South Korea, 2015: epidemiology, characteristics and public health implications. J Hosp Infect 2016 0.83
52 Vitamin C supplementation and respiratory infections: a systematic review. Mil Med 2004 0.82
53 Clove and eugenol in noncytotoxic concentrations exert immunomodulatory/anti-inflammatory action on cytokine production by murine macrophages. J Pharm Pharmacol 2012 0.82
54 The SARS-coronavirus papain-like protease: structure, function and inhibition by designed antiviral compounds. Antiviral Res 2014 0.81
55 Antiasthmatic Effects of Eugenol in a Mouse Model of Allergic Asthma by Regulation of Vitamin D3 Upregulated Protein 1/NF-κB Pathway. Inflammation 2015 0.80
56 Antiviral drugs specific for coronaviruses in preclinical development. Curr Opin Virol 2014 0.80
57 Oxidative Stress and Inflammation: What Polyphenols Can Do for Us? Oxid Med Cell Longev 2016 0.80
58 Sambucus nigra extracts inhibit infectious bronchitis virus at an early point during replication. BMC Vet Res 2014 0.79
59 Anti-inflammatory, Antithrombotic and Cardiac Remodeling Preventive Effects of Eugenol in Isoproterenol-Induced Myocardial Infarction in Wistar Rat. Cardiovasc Toxicol 2016 0.79
60 Severe Acute Respiratory Syndrome (SARS)-Lessons for Future Pandemics. Virtual Mentor 2010 0.79
61 Overviews of Biological Importance of Quercetin: A Bioactive Flavonoid. Pharmacogn Rev 2017 0.79
62 Inhibitory effects of eugenol on RANKL-induced osteoclast formation via attenuation of NF-κB and MAPK pathways. Connect Tissue Res 2014 0.78
63 Garlic and its potential for prevention of colorectal cancer and other conditions. Curr Opin Gastroenterol 2009 0.78
64 An evidence-based systematic review of elderberry and elderflower (Sambucus nigra) by the Natural Standard Research Collaboration. J Diet Suppl 2014 0.78
65 Vitamin D₃ metabolites enhance the NLRP3-dependent secretion of IL-1β from human THP-1 monocytic cells. J Cell Biochem 2015 0.78
66 Immunomodulatory activity of macromolecular polysaccharide isolated from Grifola frondosa. Chin J Nat Med 2015 0.78
67 Human blood mononuclear cell in vitro cytokine response before and after two different strenuous exercise bouts in the presence of bloodroot and Echinacea extracts. Blood Cells Mol Dis 2009 0.76
68 Mini Review of Phytochemicals and Plant Taxa with Activity as Microbial Biofilm and Quorum Sensing Inhibitors. Molecules 2015 0.76
69 Beneficial effects of cinnamon on the metabolic syndrome, inflammation, and pain, and mechanisms underlying these effects - a review. J Tradit Complement Med 2012 0.76
70 Development of animal models against emerging coronaviruses: From SARS to MERS coronavirus. Virology 2015 0.76
71 Neurovirulent Murine Coronavirus JHM.SD Uses Cellular Zinc Metalloproteases for Virus Entry and Cell-Cell Fusion. J Virol 2017 0.75
72 Public Health Network Structure and Collaboration Effectiveness during the 2015 MERS Outbreak in South Korea: An Institutional Collective Action Framework. Int J Environ Res Public Health 2017 0.75
73 MERS-CoV infection: Mind the public knowledge gap. J Infect Public Health 2017 0.75
74 Molecular Evolution of Human Coronavirus Genomes. Trends Microbiol 2016 0.75
75 [Analysis on the risk factors of severe acute respiratory syndromes coronavirus infection in workers from animal markets]. Zhonghua Liu Xing Bing Xue Za Zhi 2004 0.75
76 Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus. PLoS Pathog 2017 0.75
77 Zinc ionophore activity of quercetin and epigallocatechin-gallate: from Hepa 1-6 cells to a liposome model. J Agric Food Chem 2014 0.75
78 Quercetin and Ascorbic Acid Suppress Fructose-Induced NLRP3 Inflammasome Activation by Blocking Intracellular Shuttling of TXNIP in Human Macrophage Cell Lines. Inflammation 2017 0.75
79 Oxidative Stress and Inflammation in Cardiovascular Disease. Oxid Med Cell Longev 2017 0.75
80 Antiviral activity of Sambucus Formosana Nakai ethanol extract and related phenolic acid constituents against human coronavirus NL63. Virus Res 2019 0.75
81 Update on Nitazoxanide: A Multifunctional Chemotherapeutic Agent. Curr Drug Discov Technol 2017 0.75
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