Randomised Controlled Study of Physical Exercise Intervention in Breast Cancer Patients at Risk of Anthracycline-induced Cardiomyopathy: The EMBRACE Study (EMBRACE)

Clinical Trial ID NCT04467411

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Exercise capacity and mortality among men referred for exercise testing. N Engl J Med 2002 14.30
2 Efficacy and safety of exercise training in patients with chronic heart failure: HF-ACTION randomized controlled trial. JAMA 2009 6.36
3 Underlying causes and long-term survival in patients with initially unexplained cardiomyopathy. N Engl J Med 2000 6.27
4 American College of Sports Medicine roundtable on exercise guidelines for cancer survivors. Med Sci Sports Exerc 2010 6.18
5 Controlled trial of physical training in chronic heart failure. Exercise performance, hemodynamics, ventilation, and autonomic function. Circulation 1992 3.56
6 Java-based graphical user interface for MRUI, a software package for quantitation of in vivo/medical magnetic resonance spectroscopy signals. Comput Biol Med 2001 3.32
7 Doxorubicin-induced cardiomyopathy: from molecular mechanisms to therapeutic strategies. J Mol Cell Cardiol 2012 2.56
8 Early breast cancer therapy and cardiovascular injury. J Am Coll Cardiol 2007 2.53
9 Repeated transient mRNA bursts precede increases in transcriptional and mitochondrial proteins during training in human skeletal muscle. J Physiol 2010 1.98
10 Effect of exercise training on peak oxygen consumption in patients with cancer: a meta-analysis. Oncologist 2011 1.52
11 Dose-Response Relationship Between Physical Activity and Risk of Heart Failure: A Meta-Analysis. Circulation 2015 1.49
12 Effect of endurance exercise training on endothelial function and arterial stiffness in older patients with heart failure and preserved ejection fraction: a randomized, controlled, single-blind trial. J Am Coll Cardiol 2013 1.34
13 Using transcriptomics to identify and validate novel biomarkers of human skeletal muscle cancer cachexia. Genome Med 2010 1.18
14 Exercise training has greater effects on insulin sensitivity in daughters of patients with type 2 diabetes than in women with no family history of diabetes. Diabetologia 2008 0.92
15 Anthracycline degradation in cardiomyocytes: a journey to oxidative survival. Chem Res Toxicol 2010 0.91
16 Exercise training attenuates acute doxorubicin-induced cardiac dysfunction. J Cardiovasc Pharmacol 2006 0.91
17 Safety and efficacy of aerobic training in operable breast cancer patients receiving neoadjuvant chemotherapy: a phase II randomized trial. Acta Oncol 2013 0.91
18 2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines:  The Task Force for cancer treatments and cardiovascular toxicity of the European Society of Cardiology (ESC). Eur Heart J 2016 0.88
19 Chemotherapy-induced cardiotoxicity: detection, prevention, and management. Can J Cardiol 2014 0.87
20 Reduced in vivo high-energy phosphates precede adriamycin-induced cardiac dysfunction. Am J Physiol Heart Circ Physiol 2010 0.87
21 Anthracycline-containing chemotherapy causes long-term impairment of mitochondrial respiration and increased reactive oxygen species release in skeletal muscle. Sci Rep 2015 0.86
22 Voluntary wheel running in rats receiving doxorubicin: effects on running activity and cardiac myosin heavy chain. Anticancer Res 2009 0.79
23 Tako-Tsubo Cardiomyopathy: A Heart Stressed Out of Energy? JACC Cardiovasc Imaging 2014 0.76
24 Chemotherapy-induced cardiomyopathy. Heart Fail Rev 2015 0.76
25 Physical Activity and Prognosis in the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT) Trial. Circulation 2017 0.75
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