Selenium as a Potential Treatment for Moderately-ill, Severely-ill, and Critically-ill COVID-19 Patients. (SeCOVID)

Clinical Trial ID NCT04869579

PubWeight™ 0.00‹?›

🔗 Visit the ClinicalTrials.gov page for NCT04869579

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020 18.32
2 Selenium in Intensive Care (SIC): results of a prospective randomized, placebo-controlled, multiple-center study in patients with severe systemic inflammatory response syndrome, sepsis, and septic shock. Crit Care Med 2007 4.99
3 Coronavirus pathogenesis and the emerging pathogen severe acute respiratory syndrome coronavirus. Microbiol Mol Biol Rev 2005 3.18
4 Antioxidant nutrients: a systematic review of trace elements and vitamins in the critically ill patient. Intensive Care Med 2004 1.63
5 Selenium deficiency and viral infection. J Nutr 2003 1.45
6 Protection against reactive oxygen species by selenoproteins. Biochim Biophys Acta 2009 1.44
7 Pathological findings of COVID-19 associated with acute respiratory distress syndrome. Lancet Respir Med 2020 1.38
8 The influence of selenium on immune responses. Mol Nutr Food Res 2008 1.26
9 Evaluating selenium poisoning. Ann Clin Lab Sci 2006 1.23
10 The avian coronavirus infectious bronchitis virus undergoes direct low-pH-dependent fusion activation during entry into host cells. J Virol 2006 1.17
11 Oxidative stress in the pathogenesis of diffuse lung diseases: a review. Respir Med 2009 1.07
12 Time course and relationship between plasma selenium concentrations, systemic inflammatory response, sepsis, and multiorgan failure. Br J Anaesth 2007 0.97
13 Practicalities of selenium supplementation in critically ill patients. Curr Opin Clin Nutr Metab Care 2006 0.93
14 Selenium deficiency alters epithelial cell morphology and responses to influenza. Free Radic Biol Med 2007 0.93
15 Antioxidants and viral infections: host immune response and viral pathogenicity. J Am Coll Nutr 2001 0.93
16 Dietary selenium in adjuvant therapy of viral and bacterial infections. Adv Nutr 2015 0.89
17 Selenium supplementation suppresses tumor necrosis factor alpha-induced human immunodeficiency virus type 1 replication in vitro. AIDS Res Hum Retroviruses 1997 0.88
18 Selenium supplementation in the critically ill. Nutr Clin Pract 2012 0.86
19 Sodium selenite inhibits interleukin-6-mediated androgen receptor activation in prostate cancer cells via upregulation of c-Jun. Clin Chim Acta 2007 0.85
20 Selenium and host defence towards viruses. Proc Nutr Soc 1999 0.84
21 High-dose selenium for critically ill patients with systemic inflammation: pharmacokinetics and pharmacodynamics of selenious acid: a pilot study. Nutrition 2010 0.83
22 Risk stratification in critically ill patients: GDF-15 scores in adult respiratory distress syndrome. Crit Care 2013 0.82
23 Serum Levels of TNF-, IL-6, and Selenium in Patients with Acute and Chronic Coronary Artery Disease. Iran J Immunol 2006 0.82
24 Antioxidant effects of selenium on lung injury in paraquat intoxicated rats. Clin Toxicol (Phila) 2012 0.80
25 Selenium dependent glutathione peroxidase: a physiological regulatory system for platelet function. Thromb Haemost 1990 0.79
26 Role of Nrf2 and Autophagy in Acute Lung Injury. Curr Pharmacol Rep 2016 0.79
27 Pharmaconutrition with selenium in critically ill patients: what do we know? Nutr Clin Pract 2014 0.78
28 Selenoproteins: Antioxidant selenoenzymes and beyond. Arch Biochem Biophys 2016 0.78
29 Selenium supplementation induces metalloproteinase-dependent L-selectin shedding from monocytes. J Leukoc Biol 2008 0.78
30 Selenium enhances glutathione peroxidase activity and prostacyclin release in cultured human endothelial cells. Concurrent effects on mRNA levels. Biol Trace Elem Res 1995 0.77
31 Selenium supplementation for critically ill adults. Cochrane Database Syst Rev 2015 0.77
32 ROS Signaling in the Pathogenesis of Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome (ARDS). Adv Exp Med Biol 2017 0.75
33 Attenuation of cyclophosphamide-induced pulmonary toxicity in Swiss albino mice by naphthalimide-based organoselenium compound 2-(5-selenocyanatopentyl)-benzo[de]isoquinoline 1,3-dione. Pharm Biol 2014 0.75
34 Investigation of selenium pretreatment in the attenuation of lung injury in rats induced by fine particulate matters. Environ Sci Pollut Res Int 2016 0.75
35 Selenium in the maintenance and therapy of HIV-infected patients. Chem Biol Interact 1994 0.75
36 Selenium triggers Nrf2-mediated protection against cadmium-induced chicken hepatocyte autophagy and apoptosis. Toxicol In Vitro 2017 0.75
37 Increased levels of IL-6, IL-1β, and TNF-α in Kashin-Beck disease and rats induced by T-2 toxin and selenium deficiency. Rheumatol Int 2013 0.75
38 Studies on vitamin E and selenium deficiency in young pigs. IV. Effect on coagulation system. Can J Comp Med 1977 0.75
Next 100