Early Detection of Four Common Cancers Using the ctDNA Analysing Test (K-DETEK)

Clinical Trial ID NCT05227261

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Global cancer statistics, 2012. CA Cancer J Clin 2015 53.52
2 Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N Engl J Med 2012 44.56
3 Reduced lung-cancer mortality with low-dose computed tomographic screening. N Engl J Med 2011 38.61
4 Analysis of circulating tumor DNA to monitor metastatic breast cancer. N Engl J Med 2013 13.22
5 Circulating mutant DNA to assess tumor dynamics. Nat Med 2007 10.33
6 Detection of circulating tumor DNA in early- and late-stage human malignancies. Sci Transl Med 2014 8.36
7 Cell-free nucleic acids as biomarkers in cancer patients. Nat Rev Cancer 2011 7.69
8 ASCO 2006 update of recommendations for the use of tumor markers in gastrointestinal cancer. J Clin Oncol 2006 7.43
9 Detection and quantification of mutations in the plasma of patients with colorectal tumors. Proc Natl Acad Sci U S A 2005 5.91
10 Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor. Cell 2012 5.62
11 DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells. Cancer Res 2001 5.45
12 An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage. Nat Med 2014 4.98
13 Mutation tracking in circulating tumor DNA predicts relapse in early breast cancer. Sci Transl Med 2015 3.33
14 Efficacy of breast cancer screening by age. New results from the Swedish Two-County Trial. Cancer 1995 3.32
15 Prospective evaluation of methylated SEPT9 in plasma for detection of asymptomatic colorectal cancer. Gut 2013 2.17
16 Circulating tumor DNA as an early marker of therapeutic response in patients with metastatic colorectal cancer. Ann Oncol 2015 2.12
17 Blood markers for early detection of colorectal cancer: a systematic review. Cancer Epidemiol Biomarkers Prev 2007 2.00
18 Serum tumor markers in breast cancer: are they of clinical value? Clin Chem 2006 1.95
19 Review of biomarkers in colorectal cancer. Colorectal Dis 2012 1.59
20 Lung Cancer Statistics. Adv Exp Med Biol 2016 1.56
21 Serial monitoring of circulating tumor DNA in patients with primary breast cancer for detection of occult metastatic disease. EMBO Mol Med 2015 1.37
22 Integrated digital error suppression for improved detection of circulating tumor DNA. Nat Biotechnol 2016 1.32
23 Preoperative CA 15-3 and CEA serum levels as predictor for breast cancer outcomes. Ann Oncol 2007 1.28
24 Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients. Proc Natl Acad Sci U S A 2015 1.18
25 Performance of Lung-RADS in the National Lung Screening Trial: a retrospective assessment. Ann Intern Med 2015 1.17
26 Circulating tumor DNA analysis as a real-time method for monitoring tumor burden in melanoma patients undergoing treatment with immune checkpoint blockade. J Immunother Cancer 2014 1.14
27 The pathophysiology, clinical presentation, and diagnosis of colon cancer and adenomatous polyps. Med Clin North Am 2005 1.07
28 Plasma Septin9 versus fecal immunochemical testing for colorectal cancer screening: a prospective multicenter study. PLoS One 2014 1.03
29 Fragment Length of Circulating Tumor DNA. PLoS Genet 2016 0.87
30 The relationship between COPD and lung cancer. Lung Cancer 2015 0.85
31 Breast cancer screening methods: a review of the evidence. Health Care Women Int 2003 0.85
32 National Performance Benchmarks for Modern Screening Digital Mammography: Update from the Breast Cancer Surveillance Consortium. Radiology 2016 0.81
33 Circulating CA 15-3 antigen levels in non-mammary malignancies. Br J Cancer 1989 0.78
34 Ultra-Deep Massive Parallel Sequencing of Plasma Cell-Free DNA Enables Large-Scale Profiling of Driver Mutations in Vietnamese Patients With Advanced Non-Small Cell Lung Cancer. Front Oncol 2020 0.75
35 Survival of patients with symptom- and screening-detected colorectal cancer. Oncotarget 2016 0.75
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