Top clinical trials

Rank Clinical Trial PubWeight™‹?›
201 CATIE- Schizophrenia Trial 41.67
202 Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results (LEADER®) 41.54
203 Multiple Ascending Dose Study of Miravirsen in Treatment-Naïve Chronic Hepatitis C Subjects 41.47
204 Diabetes Prevention Program Outcomes Study (DPPOS) 41.46
205 STAMPEDE: Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy: A Multi-Stage Multi-Arm Randomised Controlled Trial (STAMPEDE) 41.45
206 Family Heart Study (FHS) 41.40
207 Hydroxyurea to Prevent Organ Damage in Children With Sickle Cell Anemia 41.38
208 Dietary Patterns, Sodium Intake and Blood Pressure (DASH - Sodium) 41.16
209 PROMISE EBF: Safety and Efficacy of Exclusive Breastfeeding Promotion in the Era of HIV in Sub-Saharan Africa 41.10
210 Exenatide Study of Cardiovascular Event Lowering Trial (EXSCEL): A Trial To Evaluate Cardiovascular Outcomes After Treatment With Exenatide Once Weekly In Patients With Type 2 Diabetes Mellitus 41.00
211 Evaluating Panitumumab (ABX-EGF) Plus Best Supportive Care Versus Best Supportive Care in Patients With Metastatic Colorectal Cancer 40.91
212 Pilot Study of AuroLase(tm) Therapy in Refractory and/or Recurrent Tumors of the Head and Neck 40.67
213 Incidence of Diabetes and Cardiovascular Disease in Mexican Americans 40.56
214 Enhancing Recovery in Coronary Heart Disease (ENRICHD) Patients 40.52
215 40.35
216 Effect of LY2062430 on the Progression of Alzheimer's Disease (EXPEDITION) 40.31
217 Study to Evaluate the Safety and Efficacy of Two Different Dosing Schedules of Pembrolizumab (MK-3475) Compared to Ipilimumab in Participants With Advanced Melanoma (MK-3475-006/KEYNOTE-006) 40.30
218 Randomized Study of Real-Time Continuous Glucose Monitors (RT-CGM) in the Management of Type 1 Diabetes 40.22
219 A Phase 1/2 Study to Evaluate MEDI4736 40.18
220 A Phase 1/2 Study of the Oral ALK/EGFR Inhibitor AP26113 40.14
221 Prevalence of Asymptomatic Ventricular Dysfunction 40.10
222 Neo ALTTO (Neoadjuvant Lapatinib and/or Trastuzumab Treatment Optimisation) Study (Neo ALTTO) 40.09
223 A Study of Pertuzumab in Addition to Chemotherapy and Trastuzumab as Adjuvant Therapy in Participants With Human Epidermal Growth Receptor 2 (HER2)-Positive Primary Breast Cancer 40.07
224 Phase III Study (Tarceva®) vs Chemotherapy to Treat Advanced Non-Small Cell Lung Cancer (NSCLC) in Patients With Mutations in the TK Domain of EGFR 39.98
225 Multi-Ethnic Study of Atherosclerosis (MESA) 39.79
226 Vaccine To Prevent Cervical Intraepithelial Neoplasia or Cervical Cancer in Younger Healthy Participants 39.77
227 A Study of Nivolumab by Itself or Nivolumab Combined With Ipilimumab in Patients With Advanced or Metastatic Solid Tumors 39.63
228 Cetuximab and Best Supportive Care Compared With Best Supportive Care Alone in Treating Patients With Metastatic Epidermal Growth Factor Receptor-Positive Colorectal Cancer 39.45
229 Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer 39.31
230 This Study Will Evaluate the Efficacy and Safety of LCZ696 Compared to Enalapril on Morbidity and Mortality of Patients With Chronic Heart Failure (PARADIGM-HF) 39.18
231 GSK1572932A Antigen-Specific Cancer Immunotherapeutic as Adjuvant Therapy in Patients With Non-Small Cell Lung Cancer 39.10
232 Multiple Class I Peptides & Montanide ISA 51 VG w Escalating Doses of Anti-PD-1 ab BMS936558 38.88
233 Study of a Drug [DCVax®-L] to Treat Newly Diagnosed GBM Brain Cancer (GBM) 38.86
234 A Study Evaluating IPI-926 in Combination With Gemcitabine in Patients With Metastatic Pancreatic Cancer 38.83
235 Determinants of Medical and Surgical Treatment Outcomes in Chronic Sinusitis 38.78
236 Tolvaptan Phase 3 Efficacy and Safety Study in ADPKD (TEMPO3/4) 38.67
237 The LIFE Study - Lifestyle Interventions and Independence for Elders (LIFE) 38.67
238 A Study Comparing GSK2118436 to Dacarbazine (DTIC) in Previously Untreated Subjects With BRAF Mutation Positive Advanced (Stage III) or Metastatic (Stage IV) Melanoma 38.65
239 Daily Everolimus in Combination With Trastuzumab and Vinorelbine in HER2/Neu Positive Women With Locally Advanced or Metastatic Breast Cancer (BOLERO-3) 38.64
240 Family Blood Pressure Program - GENOA 38.52
241 Pioglitazone vs Vitamin E vs Placebo for Treatment of Non-Diabetic Patients With Nonalcoholic Steatohepatitis (PIVENS) (PIVENS) 38.44
242 A Study Of Combined C- MET Inhibitor And PAN-HER Inhibitor (PF-02341066 And PF-00299804) In Patients With Non- Small Cell Lung Cancer 38.41
243 Cardiovascular Outcomes Study of Alogliptin in Patients With Type 2 Diabetes and Acute Coronary Syndrome (EXAMINE) 38.39
244 Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-012/KEYNOTE-012) 38.24
245 Single-dose Postpartum Vitamin A Supplementation of Mothers and Neonates (ZVITAMBO) 38.20
246 CANVAS - CANagliflozin cardioVascular Assessment Study (CANVAS) 38.20
247 Coronary Disease Morbidity and Mortality in a Population 38.11
248 Safety of PCI-32765 in Chronic Lymphocytic Leukemia 38.00
249 Lung Health Study (LHS) I and III 37.98
250 Vitamin D and Omega-3 Trial (VITAL) (VITAL) 37.94
251 Preventing Obesity Using Novel Dietary Strategies 37.73
252 ALTTO (Adjuvant Lapatinib And/Or Trastuzumab Treatment Optimisation) Study; BIG 2-06/N063D (ALTTO) 37.72
253 Physicians' Health Study II (PHS II) 37.63
254 Shock Trial: Should We Emergently Revascularize Occluded Coronaries for Cardiogenic Shock. 37.46
255 Evaluation of the Long- Term Effects of Spiriva on Lung Function in COPD Patients 37.32
256 Study Of Letrozole With Or Without Palbociclib (PD-0332991) For The First-Line Treatment Of Hormone-Receptor Positive Advanced Breast Cancer 37.24
257 Study of Two Doses of MK-3475 (Pembrolizumab) Versus Docetaxel in Previously-Treated Participants With Non-Small Cell Lung Cancer (MK-3475-010/KEYNOTE-010) 37.14
258 Evaluating the Effectiveness of Sildenafil at Improving Health Outcomes and Exercise Ability in People With Diastolic Heart Failure (The RELAX Study) (RELAX) 37.00
259 Genetics of Atherosclerosis in Mexican Americans 36.96
260 Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) (TODAY) 36.89
261 Study to Evaluate Safety, Pharmacokinetics, and Efficacy of Rociletinib (CO-1686) in Previously Treated Mutant Epidermal Growth Factor Receptor (EGFR) in Non-Small Cell Lung Cancer (NSCLC) Patients 36.89
262 Effects of Bariatric Surgery in Swedish Obese Subjects (SOS) 36.82
263 Randomized Study Comparing Docetaxel Plus Dasatinib to Docetaxel Plus Placebo in Castration-resistant Prostate Cancer (READY) 36.82
264 Aldosterone Antagonist Therapy for Adults With Heart Failure and Preserved Systolic Function (TOPCAT) 36.54
265 Neurocognitive Function in Snoring Children 36.42
266 Girls Health Enrichment Multi-Site Studies (GEMS) 36.35
267 Severe Malaria and Anti-malarial Drug Resistance in Cambodia 36.34
268 A Study of LGK974 in Patients With Malignancies Dependent on Wnt Ligands 36.26
269 An Investigational Drug, PF-02341066, Is Being Studied In Patients With Advanced Non-Small Cell Lung Cancer With A Specific Gene Profile Involving The Anaplastic Lymphoma Kinase (ALK) Gene 36.20
270 Spine Patient Outcomes Research Trial (SPORT) - Intervertebral Disc Herniation (SPORT) 36.17
271 REVEAL: Randomized EValuation of the Effects of Anacetrapib Through Lipid-modification (REVEAL) 36.08
272 Stenting vs. Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS) 36.05
273 A Study of Belimumab in Subjects With Systemic Lupus Erythematosus (SLE) (BLISS-52) 35.97
274 Fluids and Catheters Treatment Trial (FACTT) - ARDS Clinical Research Network 35.95
275 The Second Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT2) 35.94
276 Combination Chemotherapy With or Without Bevacizumab in Treating Patients With Advanced, Metastatic, or Recurrent Non-Small Cell Lung Cancer 35.85
277 Epidemiology of Cardiovascular and Non-Cardiovascular Risk In Chicago 35.80
278 Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma (ACT IV) 35.77
279 A Study of Atezolizumab Administered in Combination With Bevacizumab and/or With Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors 35.67
280 XRP6258 Plus Prednisone Compared to Mitoxantrone Plus Prednisone in Hormone Refractory Metastatic Prostate Cancer (TROPIC) 35.58
281 Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial) (TAILORx) 35.44
282 Ipilimumab With or Without Talimogene Laherparepvec in Unresected Melanoma 35.31
283 A Phase I, Dose-finding Study of the Bromodomain (Brd) Inhibitor OTX015/MK-8628 in Hematologic Malignancies (MK-8628-001) 35.27
284 Radiation Therapy With or Without Cetuximab in Treating Patients With Stage III or Stage IV Cancer of the Oropharynx, Hypopharynx, or Larynx 35.26
285 Phase III Study of ABI-007(Albumin-bound Paclitaxel) Plus Gemcitabine Versus Gemcitabine in Metastatic Adenocarcinoma of the Pancreas 35.20
286 Viral Therapy in Treating Patient With Liver Cancer 35.19
287 A Phase III Study of Radium-223 Dichloride in Patients With Symptomatic Hormone Refractory Prostate Cancer With Skeletal Metastases (ALSYMPCA) 35.16
288 A Study Of PF-05082566 As A Single Agent And In Combination With Rituximab 35.08
289 Obesity Intervention "Obeldicks" for Obese Children, Adolescents and Their Parents (Obeldicks) 35.00
290 Clarification of Optimal Anticoagulation Through Genetics (COAG) 34.94
291 EVA3S: Endarterectomy Versus Angioplasty in Patients With Severe Symptomatic Carotid Stenosis 34.91
292 Phase 2 Study of MK-3475 in Patients With Microsatellite Unstable (MSI) Tumors 34.86
293 BIBW 2992 (Afatinib) Versus Chemotherapy as First Line Treatment in NSCLC With EGFR Mutation 34.76
294 A Study of Onartuzumab (MetMAb) in Combination With Tarceva (Erlotinib) in Participants With Met Diagnostic-Positive Non-Small Cell Lung Cancer Who Have Received Chemotherapy For Advanced or Metastatic Disease (MetLung) 34.56
295 Protocolized Care for Early Septic Shock (ProCESS) 34.50
296 A Study of the Effectiveness and Safety of Nivolumab Compared to Bevacizumab and of Nivolumab With or Without Ipilimumab in Glioblastoma Patients (CheckMate 143) 34.46
297 Australasian Resuscitation In Sepsis Evaluation Randomised Controlled Trial (ARISE) 34.41
298 Patient-Physician Partnership to Improve High Blood Pressure Adherence 34.41
299 CMV-specific Cytotoxic T Lymphocytes Expressing CAR Targeting HER2 in Patients With GBM (HERT-GBM) 34.37
300 A Phase 3 Study of Ibrutinib (PCI-32765) Versus Ofatumumab in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia (RESONATE™) 34.37
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