FEBS letters (FEBS Lett)

Journal PubWeight™ 35164.62‹?›

Top papers

Rank Title Year PubWeight™‹?›
1 The use of thin acrylamide gels for DNA sequencing. 1978 40.52
2 Electrophoretic resolution of the "major outer membrane protein" of Escherichia coli K12 into four bands. 1975 26.78
3 MINT: a Molecular INTeraction database. 2002 17.21
4 'Green mice' as a source of ubiquitous green cells. 1997 17.06
5 Enhanced autoradiographic detection of 32P and 125I using intensifying screens and hypersensitized film. 1977 15.45
6 A mutation data matrix for transmembrane proteins. 1994 13.49
7 Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. 1993 13.48
8 SH3--an abundant protein domain in search of a function. 1992 12.98
9 From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair. 1997 12.43
10 Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53. 1997 11.19
11 Rank products: a simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments. 2004 11.00
12 Nucleic acid transport driven by ion gradient across cell membrane. 1980 10.49
13 Isolation of large molecular weight DNA from agarose gels for further digestion by restriction enzymes. 1975 9.87
14 SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. 1995 9.62
15 The amino acid sequence of leghaemoglobin I from root nodules of broad bean (Vicia faba L.). 1975 9.08
16 Evolution of an inducible penicillin-target protein in methicillin-resistant Staphylococcus aureus by gene fusion. 1987 8.49
17 Intrinsic resistance to beta-lactam antibiotics in Staphylococcus aureus. 1980 7.13
18 MicroRNA function in animal development. 2005 6.93
19 mTOR regulation of autophagy. 2010 6.59
20 Immunoassay using antigen-enzyme conjugates. 1971 6.40
21 Isolation of autophagocytosis mutants of Saccharomyces cerevisiae. 1994 6.35
22 Cyanobacterial microcystin-LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants. 1990 6.20
23 Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase. 1996 6.16
24 Comparative amino acid contents of purified beta-lactamases from enteric bacteria. 1970 6.15
25 Specific transport of inorganic phosphate, 3-phosphoglycerate and dihydroxyacetonephosphate, and of dicarboxylates across the inner membrane of spinach chloroplasts. 1970 5.45
26 'Quantal' Ca2+ release and the control of Ca2+ entry by inositol phosphates--a possible mechanism. 1990 5.35
27 SR141716A, a potent and selective antagonist of the brain cannabinoid receptor. 1994 5.30
28 The logic of TGFbeta signaling. 2006 5.26
29 LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity. 2000 5.22
30 Management of cellular energy by the AMP-activated protein kinase system. 2003 5.22
31 High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria. 1997 5.21
32 Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes. 1990 5.14
33 Close evolutionary relationship between the chromosomally encoded beta-lactamase gene of Klebsiella pneumoniae and the TEM beta-lactamase gene mediated by R plasmids. 1986 5.13
34 Superoxide-dependent production of hydroxyl radical catalyzed by iron-EDTA complex. 1978 5.12
35 A solubilizable acrylamide gel for electrophoresis. 1970 5.09
36 Inhibition of actin polymerization by latrunculin A. 1987 5.06
37 Bromodomain: an acetyl-lysine binding domain. 2002 5.03
38 RNA-binding proteins and post-transcriptional gene regulation. 2008 5.00
39 Membrane receptor dependent iron transport in Escherichia coli. 1975 5.00
40 EST comparison indicates 38% of human mRNAs contain possible alternative splice forms. 2000 4.96
41 Computerized microacidimetric determination of beta lactamase Michaelis-Menten constants. 1973 4.95
42 ER beta: identification and characterization of a novel human estrogen receptor. 1996 4.77
43 Human monocyte chemoattractant protein-1 (MCP-1). Full-length cDNA cloning, expression in mitogen-stimulated blood mononuclear leukocytes, and sequence similarity to mouse competence gene JE. 1989 4.75
44 Pannexin membrane channels are mechanosensitive conduits for ATP. 2004 4.73
45 The primary structure of transcription factor TFIIIA has 12 consecutive repeats. 1985 4.73
46 Hydrophobic cluster analysis: an efficient new way to compare and analyse amino acid sequences. 1987 4.71
47 Dicing and slicing: the core machinery of the RNA interference pathway. 2005 4.63
48 Cyclic AMP as an antagonist of catabolite repression in Escherichia coli. 1968 4.60
49 CpG islands--'a rough guide'. 2009 4.55
50 A semi-empirical method for prediction of antigenic determinants on protein antigens. 1990 4.49
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