Antimicrobial agents and chemotherapy (Antimicrob Agents Chemother)

Journal PubWeight™ 31816.20‹?›

Top papers

Rank Title Year PubWeight™‹?›
1 Novel method for detection of beta-lactamases by using a chromogenic cephalosporin substrate. 1972 61.10
2 A functional classification scheme for beta-lactamases and its correlation with molecular structure. 1995 26.51
3 In vitro antibacterial activity of AM-715, a new nalidixic acid analog. 1980 26.28
4 Method of reliable determination of minimal lethal antibiotic concentrations. 1980 23.54
5 In vitro activity of Bay 09867, a new quinoline derivative, compared with those of other antimicrobial agents. 1983 21.48
6 In vitro and in vivo activity of DL-8280, a new oxazine derivative. 1982 21.31
7 Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique. 1979 17.49
8 Laboratory evaluation of a rapid, automatic susceptibility testing system: report of a collaborative study. 1975 17.12
9 Novel carbapenem-hydrolyzing beta-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae. 2001 16.97
10 Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India. 2009 16.90
11 Multiplex PCR strategy for rapid identification of structural types and variants of the mec element in methicillin-resistant Staphylococcus aureus. 2002 15.11
12 Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy. 2002 13.91
13 Structural comparison of three types of staphylococcal cassette chromosome mec integrated in the chromosome in methicillin-resistant Staphylococcus aureus. 2001 12.65
14 PCR mapping of integrons reveals several novel combinations of resistance genes. 1995 12.54
15 Quinolone resistance-determining region in the DNA gyrase gyrA gene of Escherichia coli. 1990 11.71
16 Clavulanic acid: a beta-lactamase-inhiting beta-lactam from Streptomyces clavuligerus. 1977 11.58
17 The fluoroquinolones: structures, mechanisms of action and resistance, and spectra of activity in vitro. 1985 11.34
18 More extended-spectrum beta-lactamases. 1991 11.28
19 Comparative in vitro activity of Mk-0366 and other selected oral antimicrobial agents against Neisseria gonorrhoeae. 1981 11.11
20 In vitro antimicrobial susceptibility of anaerobic bacteria isolated from clinical specimens. 1972 11.05
21 Cefamandole, a cephalosporin antibiotic with an unusually wide spectrum of activity. 1974 10.72
22 Growing group of extended-spectrum beta-lactamases: the CTX-M enzymes. 2004 10.64
23 HR 756, a new cephalosporin active against gram-positive and gram-negative aerobic and anaerobic bacteria. 1979 10.60
24 Cefuroxime, a new cephalosporin antibiotic: activity in vitro. 1976 10.56
25 Detection of erythromycin-resistant determinants by PCR. 1996 10.56
26 In vitro activity of norfloxacin, a quinolinecarboxylic acid, compared with that of beta-lactams, aminoglycosides, and trimethoprim. 1982 10.08
27 Characterization of VIM-2, a carbapenem-hydrolyzing metallo-beta-lactamase and its plasmid- and integron-borne gene from a Pseudomonas aeruginosa clinical isolate in France. 2000 10.05
28 Antibacterial activity of a new 1-oxa cephalosporin compared with that of other beta-lactam compounds. 1979 10.01
29 A new class of genetic element, staphylococcus cassette chromosome mec, encodes methicillin resistance in Staphylococcus aureus. 2000 9.84
30 Cefoxitin, a semisynthetic cephamycin antibiotic: antibacterial spectrum and resistance to hydrolysis by gram-negative beta-lactamases. 1974 9.66
31 Azthreonam (SQ 26,776), a synthetic monobactam specifically active against aerobic gram-negative bacteria. 1982 9.58
32 Susceptibility of anaerobic bacteria to 23 antimicrobial agents. 1976 9.53
33 Erythromycin resistance by ribosome modification. 1995 9.40
34 Medium for use in antibiotic susceptibility testing of anaerobic bacteria. 1976 9.38
35 Modified broth-disk method for testing the antibiotic susceptibility of anaerobic bacteria. 1973 9.35
36 Microplate alamar blue assay versus BACTEC 460 system for high-throughput screening of compounds against Mycobacterium tuberculosis and Mycobacterium avium. 1997 9.16
37 Resistance of Candida species to fluconazole. 1995 9.04
38 MK0787 (N-formimidoyl thienamycin): evaluation of in vitro and in vivo activities. 1980 9.02
39 Cloning and characterization of blaVIM, a new integron-borne metallo-beta-lactamase gene from a Pseudomonas aeruginosa clinical isolate. 1999 9.01
40 Susceptibility of anaerobes to cefoxitin and other cephalosporins. 1975 8.86
41 Cefoxitin, a semisynthetic cephamycin antibiotic: resistance to beta-lactamase inactivation. 1974 8.84
42 Antibacterial activity of cefamandole, a new cephalosporin antibiotic, compared with that of cephaloridine, cephalothin, and cephalexin. 1973 8.83
43 Pharmacokinetics and tissue penetration of ciprofloxacin. 1983 8.82
44 BRL 17421, a novel beta-lactam antibiotic, highly resistant to beta-lactamases, giving high and prolonged serum levels in humans. 1981 8.81
45 In vitro activity of thienamycin. 1978 8.76
46 Pipemidic acid, a new antibacterial agent active against Pseudomonas aeruginosa: in vitro properties. 1975 8.67
47 Role of an altered penicillin-binding protein in methicillin- and cephem-resistant Staphylococcus aureus. 1985 8.66
48 Streptococcus pneumoniae and Streptococcus pyogenes resistant to macrolides but sensitive to clindamycin: a common resistance pattern mediated by an efflux system. 1996 8.65
49 Molecular characterization of an enterobacterial metallo beta-lactamase found in a clinical isolate of Serratia marcescens that shows imipenem resistance. 1994 8.64
50 Ciprofloxacin, a quinolone carboxylic acid compound active against aerobic and anaerobic bacteria. 1984 8.62
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