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Science (New York, N.Y.) (Science)
Journal PubWeight™ 126635.94
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Top papers
Rank
Title
Year
PubWeight™
‹?›
1
Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase.
1988
220.77
2
The sequence of the human genome.
2001
101.55
3
Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia.
1985
95.08
4
Emergence of scaling in random networks
1999
89.38
5
Quantitative monitoring of gene expression patterns with a complementary DNA microarray.
1995
88.48
6
The complete genome sequence of Escherichia coli K-12.
1997
84.27
7
Screening lambdagt recombinant clones by hybridization to single plaques in situ.
1977
83.82
8
Molecular classification of cancer: class discovery and class prediction by gene expression monitoring.
1999
83.27
9
Rapid and sensitive protein similarity searches.
1985
76.83
10
The Evolution of Oxygen From Illuminated Suspensions of Frozen, Dried, and Homogenized Chloroplasts.
1946
74.78
11
The genome sequence of Drosophila melanogaster.
2000
74.32
12
Induced pluripotent stem cell lines derived from human somatic cells.
2007
71.50
13
Optimization by simulated annealing.
1983
71.02
14
Whole-genome random sequencing and assembly of Haemophilus influenzae Rd.
1995
68.34
15
Multilineage potential of adult human mesenchymal stem cells.
1999
66.19
16
Embryonic stem cell lines derived from human blastocysts.
1998
65.53
17
Genome-wide mapping of in vivo protein-DNA interactions.
2007
64.92
18
The future of genetic studies of complex human diseases.
1996
64.76
19
EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy.
2004
61.56
20
Genome sequence of the nematode C. elegans: a platform for investigating biology.
1998
61.48
21
MENDELIAN PROPORTIONS IN A MIXED POPULATION.
1908
60.99
22
Exploring the metabolic and genetic control of gene expression on a genomic scale.
1997
60.15
23
Serial analysis of gene expression.
1995
60.15
24
The consensus coding sequences of human breast and colorectal cancers.
2006
60.02
25
Human malaria parasites in continuous culture.
1976
59.70
26
Optical coherence tomography.
1991
57.87
27
Translating the histone code.
2001
56.77
28
Multiplex genome engineering using CRISPR/Cas systems.
2013
55.53
29
Amino acid metabolism in mammalian cell cultures.
1959
55.21
30
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.
2007
51.70
31
An integrated genomic analysis of human glioblastoma multiforme.
2008
51.36
32
The structure of haplotype blocks in the human genome.
2002
50.88
33
A genomic perspective on protein families.
1997
50.51
34
Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene.
1987
49.88
35
Understanding the Warburg effect: the metabolic requirements of cell proliferation.
2009
49.82
36
Diversity of the human intestinal microbial flora.
2005
49.64
37
On the origin of cancer cells.
1956
49.55
38
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics.
2002
49.51
39
The transcriptional landscape of the yeast genome defined by RNA sequencing.
2008
48.99
40
RNA-guided human genome engineering via Cas9.
2013
48.29
41
A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.
2012
48.17
42
TRANSMISSION OF INFLUENZA BY A FILTERABLE VIRUS.
1934
47.63
43
Environmental genome shotgun sequencing of the Sargasso Sea.
2004
45.23
44
Electric field effect in atomically thin carbon films.
2004
45.10
45
The tragedy of the commons. The population problem has no technical solution; it requires a fundamental extension in morality.
1968
45.05
46
Neighborhoods and violent crime: a multilevel study of collective efficacy.
1997
44.65
47
Identification of novel genes coding for small expressed RNAs.
2001
44.44
48
An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans.
2001
44.16
49
Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS).
1983
43.61
50
Two-photon laser scanning fluorescence microscopy.
1990
43.55
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