Nucleic acids research (Nucleic Acids Res)

Journal PubWeight™ 61743.75‹?›

Top papers

Rank Title Year PubWeight™‹?›
1 Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. 1997 665.31
2 CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. 1994 392.47
3 A rapid alkaline extraction procedure for screening recombinant plasmid DNA. 1979 214.95
4 The Protein Data Bank. 2000 187.10
5 A comprehensive set of sequence analysis programs for the VAX. 1984 181.98
6 The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. 1997 175.36
7 MUSCLE: multiple sequence alignment with high accuracy and high throughput. 2004 168.89
8 tRNAscan-SE: a program for improved detection of transfer RNA genes in genomic sequence. 1997 142.55
9 A new mathematical model for relative quantification in real-time RT-PCR. 2001 124.61
10 Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. 1983 124.30
11 KEGG: kyoto encyclopedia of genes and genomes. 2000 117.00
12 Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. 1984 86.56
13 RNAmmer: consistent and rapid annotation of ribosomal RNA genes. 2007 85.81
14 Mfold web server for nucleic acid folding and hybridization prediction. 2003 77.89
15 A simple salting out procedure for extracting DNA from human nucleated cells. 1988 77.80
16 dbSNP: the NCBI database of genetic variation. 2001 76.97
17 Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. 2002 76.95
18 The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000. 2000 67.44
19 Optimal computer folding of large RNA sequences using thermodynamics and auxiliary information. 1981 61.59
20 ARB: a software environment for sequence data. 2004 58.27
21 The Pfam protein families database. 2004 56.46
22 Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. 2008 54.83
23 The Gene Ontology (GO) database and informatics resource. 2004 54.37
24 The KEGG resource for deciphering the genome. 2004 53.05
25 A system for shotgun DNA sequencing. 1981 52.99
26 The SWISS-PROT protein knowledgebase and its supplement TrEMBL in 2003. 2003 52.80
27 Summaries of Affymetrix GeneChip probe level data. 2003 52.74
28 The Ribosomal Database Project: improved alignments and new tools for rRNA analysis. 2008 52.43
29 SIFT: Predicting amino acid changes that affect protein function. 2003 52.26
30 Improved microbial gene identification with GLIMMER. 1999 51.34
31 The Pfam protein families database. 2002 51.34
32 Human non-synonymous SNPs: server and survey. 2002 50.45
33 Rapid isolation of high molecular weight plant DNA. 1980 50.26
34 KEGG for linking genomes to life and the environment. 2007 49.37
35 The COG database: a tool for genome-scale analysis of protein functions and evolution. 2000 49.22
36 Tandem repeats finder: a program to analyze DNA sequences. 1999 49.21
37 NCBI reference sequences (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins. 2006 48.10
38 DNA polymorphisms amplified by arbitrary primers are useful as genetic markers. 1990 47.84
39 MAFFT: a novel method for rapid multiple sequence alignment based on fast Fourier transform. 2002 47.62
40 Sequence data handling by computer. 1977 45.33
41 RefSeq and LocusLink: NCBI gene-centered resources. 2001 45.29
42 AFLP: a new technique for DNA fingerprinting. 1995 45.26
43 From genomics to chemical genomics: new developments in KEGG. 2006 44.35
44 ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data. 2010 43.51
45 The COG database: new developments in phylogenetic classification of proteins from complete genomes. 2001 43.17
46 The Pfam protein families database. 2000 42.28
47 The Ensembl genome database project. 2002 40.87
48 KEGG: Kyoto Encyclopedia of Genes and Genomes. 1999 40.62
49 Rapid and efficient cosmid cloning. 1981 40.13
50 Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation. 2002 40.03
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