| Rank |
Title |
Year |
PubWeight™‹?› |
|
1
|
Cell cycle arrest in Metformin treated breast cancer cells involves activation of AMPK, downregulation of cyclin D1, and requires p27Kip1 or p21Cip1.
|
2008
|
1.96
|
|
2
|
Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer.
|
2010
|
1.94
|
|
3
|
Gadd45 in stress signaling.
|
2008
|
1.42
|
|
4
|
Abundance, complexation, and trafficking of Wnt/beta-catenin signaling elements in response to Wnt3a.
|
2007
|
1.27
|
|
5
|
The dietary bioflavonoid quercetin synergizes with epigallocathechin gallate (EGCG) to inhibit prostate cancer stem cell characteristics, invasion, migration and epithelial-mesenchymal transition.
|
2010
|
1.26
|
|
6
|
TRAF molecules in cell signaling and in human diseases.
|
2013
|
1.22
|
|
7
|
Multiple paxillin binding sites regulate FAK function.
|
2008
|
1.19
|
|
8
|
Molecular mechanisms mediating the G protein-coupled receptor regulation of cell cycle progression.
|
2007
|
1.19
|
|
9
|
Canonical Wnt signaling is involved in switching from cell proliferation to myogenic differentiation of mouse myoblast cells.
|
2011
|
1.17
|
|
10
|
Signaling in colon cancer stem cells.
|
2012
|
1.15
|
|
11
|
Inhibition of PI3K/AKT and MEK/ERK pathways act synergistically to enhance antiangiogenic effects of EGCG through activation of FOXO transcription factor.
|
2008
|
1.13
|
|
12
|
EGFR/Met association regulates EGFR TKI resistance in breast cancer.
|
2010
|
1.11
|
|
13
|
Src homology 2 (SH2) domain containing protein tyrosine phosphatase-1 (SHP-1) dephosphorylates VEGF Receptor-2 and attenuates endothelial DNA synthesis, but not migration*.
|
2008
|
1.11
|
|
14
|
Rac inhibits thrombin-induced Rho activation: evidence of a Pak-dependent GTPase crosstalk.
|
2006
|
1.06
|
|
15
|
AMPK exerts dual regulatory effects on the PI3K pathway.
|
2010
|
1.05
|
|
16
|
Combination of dasatinib and curcumin eliminates chemo-resistant colon cancer cells.
|
2011
|
1.05
|
|
17
|
Role of RGM coreceptors in bone morphogenetic protein signaling.
|
2007
|
1.01
|
|
18
|
Curcumin enhances the apoptosis-inducing potential of TRAIL in prostate cancer cells: molecular mechanisms of apoptosis, migration and angiogenesis.
|
2007
|
1.01
|
|
19
|
Ligand-dependent localization and intracellular stability of sigma-1 receptors in CHO-K1 cells.
|
2007
|
1.01
|
|
20
|
Sensitization of TRAIL-resistant LNCaP cells by resveratrol (3, 4', 5 tri-hydroxystilbene): molecular mechanisms and therapeutic potential.
|
2007
|
0.99
|
|
21
|
Membrane estrogen receptor-alpha-mediated nongenomic actions of phytoestrogens in GH3/B6/F10 pituitary tumor cells.
|
2009
|
0.98
|
|
22
|
G-protein-coupled receptor-associated A-kinase anchoring proteins AKAP5 and AKAP12: differential signaling to MAPK and GPCR recycling.
|
2008
|
0.96
|
|
23
|
The neurotransmitter dopamine modulates vascular permeability in the endothelium.
|
2008
|
0.96
|
|
24
|
AMPK-induced activation of Akt by AICAR is mediated by IGF-1R dependent and independent mechanisms in acute lymphoblastic leukemia.
|
2010
|
0.96
|
|
25
|
Estradiol effects on the dopamine transporter - protein levels, subcellular location, and function.
|
2006
|
0.94
|
|
26
|
NFAT5 in cellular adaptation to hypertonic stress - regulations and functional significance.
|
2013
|
0.94
|
|
27
|
Rad6B acts downstream of Wnt signaling to stabilize β-catenin: Implications for a novel Wnt/β-catenin target.
|
2011
|
0.93
|
|
28
|
Clusterin expression can be modulated by changes in TCF1-mediated Wnt signaling.
|
2007
|
0.92
|
|
29
|
Membrane TNF-alpha-activated programmed necrosis is mediated by Ceramide-induced reactive oxygen species.
|
2013
|
0.92
|
|
30
|
The roles played by highly truncated splice variants of G protein-coupled receptors.
|
2012
|
0.92
|
|
31
|
Glycogen Synthase Kinase-3beta regulates Snail and beta-catenin during gastrin-induced migration of gastric cancer cells.
|
2010
|
0.91
|
|
32
|
A novel mechanism of cell growth regulation by Cell Cycle and Apoptosis Regulatory Protein (CARP)-1.
|
2010
|
0.91
|
|
33
|
SFRP-4 abrogates Wnt-3a-induced beta-catenin and Akt/PKB signalling and reverses a Wnt-3a-imposed inhibition of in vitro mammary differentiation.
|
2008
|
0.91
|
|
34
|
Overexpression of tissue inhibitors of metalloproteinase 2 up-regulates NF-kappaB activity in melanoma cells.
|
2009
|
0.88
|
|
35
|
Dual function of polycomb group proteins in differentiated murine T helper (CD4+) cells.
|
2011
|
0.88
|
|
36
|
Brain-derived neurotrophic factor receptor TrkB exists as a preformed dimer in living cells.
|
2012
|
0.88
|
|
37
|
Enhanced catharanthine and vindoline production in suspension cultures of Catharanthus roseus by ultraviolet-B light.
|
2008
|
0.88
|
|
38
|
Multiple functions of G protein-coupled receptor kinases.
|
2014
|
0.87
|
|
39
|
Glucocorticoid evoked upregulation of RCAN1-1 in human leukemic CEM cells susceptible to apoptosis.
|
2009
|
0.87
|
|
40
|
siRNA knockdown of GPR18 receptors in BV-2 microglia attenuates N-arachidonoyl glycine-induced cell migration.
|
2012
|
0.86
|
|
41
|
Tumour promoting and suppressing roles of the atypical MAP kinase signalling pathway ERK3/4-MK5.
|
2012
|
0.86
|
|
42
|
The adaptor protein p62/SQSTM1 in osteoclast signaling pathways.
|
2012
|
0.86
|
|
43
|
The alpha1D-adrenergic receptor is expressed intracellularly and coupled to increases in intracellular calcium and reactive oxygen species in human aortic smooth muscle cells.
|
2008
|
0.85
|
|
44
|
Caspase-3 mediated release of SAC domain containing fragment from Par-4 is necessary for the sphingosine-induced apoptosis in Jurkat cells.
|
2013
|
0.85
|
|
45
|
Zinc release from thapsigargin/IP3-sensitive stores in cultured cortical neurons.
|
2010
|
0.85
|
|
46
|
G-patch domain and KOW motifs-containing protein, GPKOW; a nuclear RNA-binding protein regulated by protein kinase A.
|
2011
|
0.85
|
|
47
|
Wnt and Frizzled RNA expression in human mesenchymal and embryonic (H7) stem cells.
|
2008
|
0.84
|
|
48
|
Neuronal aging: learning from C. elegans.
|
2013
|
0.84
|
|
49
|
Genetic and functional characterization of putative Ras/Raf interaction inhibitors in C. elegans and mammalian cells.
|
2010
|
0.84
|
|
50
|
E4BP4 facilitates glucocorticoid-evoked apoptosis of human leukemic CEM cells via upregulation of Bim.
|
2011
|
0.84
|