The Journal of experimental medicine (J Exp Med)

Journal PubWeight™ 41807.93‹?›

Top papers

Rank Title Year PubWeight™‹?›
1 A study of fixation for electron microscopy. 1952 121.17
2 THE ELABORATION OF SPECIFIC SOLUBLE SUBSTANCE BY PNEUMOCOCCUS DURING GROWTH. 1917 80.64
3 Plaque formation and isolation of pure lines with poliomyelitis viruses. 1954 68.67
4 THE LATENT PERIOD IN THE GROWTH OF BACTERIA. 1916 46.86
5 THE SOLUBLE SPECIFIC SUBSTANCE OF PNEUMOCOCCUS : THIRD PAPER. 1925 44.30
6 Localization of antigen in tissue cells; improvements in a method for the detection of antigen by means of fluorescent antibody. 1950 43.56
7 FURTHER STUDIES ON BACTERIAL HYPERSUSCEPTIBILITY. II. 1923 42.15
8 A FURTHER STUDY OF THE BACTERICIDAL ACTION OF ETHYLHYDROCUPREIN ON PNEUMOCOCCI. 1915 40.58
9 THE SOLUBLE SPECIFIC SUBSTANCE OF PNEUMOCOCCUS : SECOND PAPER. 1924 38.49
10 THE ACTION OF ETHYLHYDROCUPREIN (OPTOCHIN) ON TYPE STRAINS OF PNEUMOCOCCI IN VITRO AND IN VIVO, AND ON SOME OTHER MICROORGANISMS IN VITRO. 1915 36.35
11 THE SOLUBLE SPECIFIC SUBSTANCE OF PNEUMOCOCCUS. 1923 32.69
12 EXPERIMENTAL PNEUMONIA BY INTRABRONCHIAL INSUFFLATION. 1912 31.80
13 Cellular resistance to infection. 1962 30.96
14 Immunization of dissociated spleen cell cultures from normal mice. 1967 30.93
15 The adsorption of proteins on erythrocytes treated with tannic acid and subsequent hemagglutination by antiprotein sera. 1951 29.48
16 A SARCOMA OF THE FOWL TRANSMISSIBLE BY AN AGENT SEPARABLE FROM THE TUMOR CELLS. 1911 29.44
17 IMMUNOLOGICAL RELATIONSHIPS OF CELL CONSTITUENTS OF PNEUMOCOCCUS : SECOND PAPER. 1925 29.02
18 IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. 2005 28.73
19 Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. 2003 26.05
20 Studies on the propagation in vitro of poliomyelitis viruses. IV. Viral multiplication in a stable strain of human malignant epithelial cells (strain HeLa) derived from an epidermoid carcinoma of the cervix. 1953 25.88
21 STUDIES ON THE TUBERCULIN REACTION AND ON SPECIFIC HYPERSENSITIVENESS IN BACTERIAL INFECTION. 1921 25.29
22 Surface markers on human T and B lymphocytes. I. A large population of lymphocytes forming nonimmune rosettes with sheep red blood cells. 1972 24.43
23 Structure and development of viruses observed in the electron microscope. II. Vaccinia and fowl pox viruses. 1954 24.15
24 VARIETIES OF PNEUMOCOCCUS AND THEIR RELATION TO LOBAR PNEUMONIA. 1915 24.12
25 STUDIES ON THE CHEMICAL NATURE OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES : INDUCTION OF TRANSFORMATION BY A DESOXYRIBONUCLEIC ACID FRACTION ISOLATED FROM PNEUMOCOCCUS TYPE III. 1944 24.08
26 The chemotactic effect of mixtures of antibody and antigen on polymorphonuclear leucocytes. 1962 23.03
27 STUDIES ON THE BIOLOGY OF STREPTOCOCCUS : I. ANTIGENIC RELATIONSHIPS BETWEEN STRAINS OF STREPTOCOCCUS HAEMOLYTICUS. 1919 22.91
28 A QUANTITATIVE STUDY OF THE PRECIPITIN REACTION BETWEEN TYPE III PNEUMOCOCCUS POLYSACCHARIDE AND PURIFIED HOMOLOGOUS ANTIBODY. 1929 22.71
29 Clonal growth of mammalian cells in vitro; growth characteristics of colonies from single HeLa cells with and without a feeder layer. 1956 22.68
30 IMMUNOLOGICAL RELATIONSHIPS OF CELL CONSTITUENTS OF PNEUMOCOCCUS. 1923 22.54
31 A STUDY OF TISSUE CULTURE CELLS BY ELECTRON MICROSCOPY : METHODS AND PRELIMINARY OBSERVATIONS. 1945 22.42
32 Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. 1992 22.13
33 THE DIFFERENTIATION OF MONONUCLEAR PHAGOCYTES. MORPHOLOGY, CYTOCHEMISTRY, AND BIOCHEMISTRY. 1965 21.86
34 Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. 1994 21.52
35 THE RELATIVE REACTION WITHIN LIVING MAMMALIAN TISSUES : IV. INDICATED DIFFERENCES IN THE REACTION OF THE ORGANS ON VITAL STAINING WITH PHTHALEINS. 1925 21.41
36 ON THE PERMANENT LIFE OF TISSUES OUTSIDE OF THE ORGANISM. 1912 21.31
37 The isolation and properties of the specific cytoplasmic granules of rabbit polymorphonuclear leucocytes. 1960 21.07
38 The influence of immunologically committed lymphoid cells on macrophage activity in vivo. 1969 20.62
39 VIRULENCE AND MORPHOLOGICAL CHARACTERISTICS OF MAMMALIAN TUBERCLE BACILLI. 1947 20.55
40 SPECIFIC PRECIPITATION AND MOUSE PROTECTION IN TYPE I ANTIPNEUMOCOCCUS SERA. 1930 20.13
41 Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. 2000 19.81
42 CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. 1998 19.03
43 THE PROTECTION OF PATHOGENIC MICROORGANISMS BY LIVING TISSUE CELLS. 1916 18.60
44 An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection. 1993 18.56
45 One-step growth curve of Western equine encephalomyelitis virus on chicken embryo cells grown in vitro and analysis of virus yields from single cells. 1954 17.92
46 THE USE OF THE FINAL HYDROGEN ION CONCENTRATION IN DIFFERENTIATION OF STREPTOCOCCUS HAEMOLYTICUS OF HUMAN AND BOVINE TYPES. 1919 17.61
47 Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. 1996 17.51
48 TYPING GROUP A HEMOLYTIC STREPTOCOCCI BY M PRECIPITIN REACTIONS IN CAPILLARY PIPETTES. 1943 17.30
49 Interactions between rabbit polymorphonuclear leucocytes and staphylococci. 1959 17.17
50 Functional subclasses of T-lymphocytes bearing different Ly antigens. I. The generation of functionally distinct T-cell subclasses is a differentiative process independent of antigen. 1975 17.16
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