Journal of immunology (Baltimore, Md. : 1950) (J Immunol)

Journal PubWeight™ 68207.80‹?›

Top papers

Rank Title Year PubWeight™‹?›
1 Application of a microtechnique to viral serological investigations. 1962 51.33
2 Rapid isolation of antigens from cells with a staphylococcal protein A-antibody adsorbent: parameters of the interaction of antibody-antigen complexes with protein A. 1975 47.77
3 Enzyme-linked immunosorbent assay, Elisa. 3. Quantitation of specific antibodies by enzyme-labeled anti-immunoglobulin in antigen-coated tubes. 1972 40.51
4 Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. 1986 35.41
5 Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. 1995 29.42
6 T cell growth factor: parameters of production and a quantitative microassay for activity. 1978 28.92
7 Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. 1984 17.76
8 Micromethods for the study of proteins and antibodies. I. Procedure and general applications of hemagglutination and hemagglutination-inhibition reactions with tannic acid and protein-treated red blood cells. 1954 17.47
10 Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. 1999 16.86
11 A new mouse myeloma cell line that has lost immunoglobulin expression but permits the construction of antibody-secreting hybrid cell lines. 1979 16.56
13 Current knowledge of type-specific M antigens of group A streptococci. 1962 14.71
14 Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule. 1983 14.36
15 Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. 1988 14.21
16 IL-10 inhibits cytokine production by activated macrophages. 1991 13.13
18 Studies on immunization against plague. I. The isolation and characterization of the soluble antigen of Pasteurella pestis. 1952 12.34
19 CD4+CD25high regulatory cells in human peripheral blood. 2001 11.25
20 Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. 1992 11.24
21 Quantitative micro-complement fixation and its use in the study of antigenic structure by specific antigen-antibody inhibition. 1961 11.21
22 IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells. 1991 11.04
23 Studies on treponemal immobilizing antibodies in syphilis. I. Techniques of measurement and factors influencing immobilization. 1951 11.01
24 Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1). 1986 10.92
25 A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells. I. Production of anti-Tac monoclonal antibody and distribution of Tac (+) cells. 1981 10.92
26 Of mice and not men: differences between mouse and human immunology. 2004 10.61
27 IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis. 2006 10.33
28 IgG or IgM monoclonal antibodies reactive with different determinants on the molecular complex bearing Lyt 2 antigen block T cell-mediated cytolysis in the absence of complement. 1980 10.30
29 Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice. 2003 10.21
30 Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis. 1981 9.86
31 Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression. 2006 9.82
32 Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells. 2005 9.76
33 Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells. 2010 9.72
34 "Protein A" from S. aureus. I. Pseudo-immune reaction with human gamma-globulin. 1966 9.65
35 Studies on pulmonary alveolar macrophages from the normal rabbit: a technique to procure them in a high state of purity. 1961 9.52
36 Myeloid-derived suppressor cells: linking inflammation and cancer. 2009 9.41
37 Pathogenesis of experimental cholera: biologic ativities of purified procholeragen A. 1966 9.39
38 A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R. 2002 9.30
39 Detection of immune complexes in unheated sera by modified 125I-Clq binding test. Effect of heating on the binding of Clq by immune complexes and application of the test to systemic lupus erythematosus. 1976 9.28
40 Subsets of myeloid-derived suppressor cells in tumor-bearing mice. 2008 9.25
41 Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity. 2005 9.17
42 Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific. 2000 9.15
43 Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance. 1999 8.98
44 Antigen elimination from the blood as an early manifestation of the immune response. 1951 8.92
45 Chromatographic purification of tetramethylrhodamine-immune globulin conjugates and their use in the cellular localization of rabbit gamma-globulin polypeptide chains. 1965 8.88
46 Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response. 2004 8.65
47 Monoclonal antibodies to Chlamydia trachomatis: antibody specificities and antigen characterization. 1982 8.61
48 Hybridoma cell lines secreting monoclonal antibodies to mouse H-2 and Ia antigens. 1980 8.56
49 Studies of arthritis and other lesions induced in rats by injection of mycobacterial adjuvant. II. Evidence that the disease is a disseminated immunologic response to exogenous antigen. 1960 8.51
50 Typing of viruses by combinations of antiserum pools. Application to typing of enteroviruses (Coxsackie and ECHO). 1960 8.41
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