The Journal of biological chemistry (J Biol Chem)

Journal PubWeight™ 193144.36‹?›

Top papers

Rank Title Year PubWeight™‹?›
1 Protein measurement with the Folin phenol reagent. 1951 1743.91
2 A simple method for the isolation and purification of total lipides from animal tissues. 1957 173.99
3 The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis. 1969 142.11
4 High resolution two-dimensional electrophoresis of proteins. 1975 133.45
5 Acetylornithinase of Escherichia coli: partial purification and some properties. 1956 93.84
6 A new generation of Ca2+ indicators with greatly improved fluorescence properties. 1985 90.20
7 Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis. 1977 72.51
8 Phosphorus assay in column chromatography. 1959 60.56
9 A method for determining the sedimentation behavior of enzymes: application to protein mixtures. 1961 59.20
10 Notes on sugar determination. 1952 44.34
11 Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). 1969 43.83
12 The thiobarbituric acid assay of sialic acids. 1959 43.78
13 The regulation of rabbit skeletal muscle contraction. I. Biochemical studies of the interaction of the tropomyosin-troponin complex with actin and the proteolytic fragments of myosin. 1971 35.39
14 Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes. 1987 34.69
15 Mechanism of assembly of the outer membrane of Salmonella typhimurium. Isolation and characterization of cytoplasmic and outer membrane. 1972 29.60
16 DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. 1998 28.13
17 Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. 1974 27.82
18 The chromatographic identification of some biologically important phosphate esters. 1951 26.34
19 Phase separation of integral membrane proteins in Triton X-114 solution. 1981 26.33
20 THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE. 1964 24.57
21 FORMATION OF METHANE BY BACTERIAL EXTRACTS. 1963 24.25
22 A modified ninhydrin reagent for the photometric determination of amino acids and related compounds. 1954 23.09
23 A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase. 1952 22.93
24 The release of enzymes from Escherichia coli by osmotic shock and during the formation of spheroplasts. 1965 22.76
25 p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. 2007 21.73
26 The role of polyamines in the neutralization of bacteriophage deoxyribonucleic acid. 1960 21.21
27 Chromatography of amino acids on sulfonated polystyrene resins. 1951 21.20
28 METABOLISM OF ISOLATED FAT CELLS. I. EFFECTS OF HORMONES ON GLUCOSE METABOLISM AND LIPOLYSIS. 1964 21.04
29 The determination of hydroxyproline. 1950 20.59
30 Reagents for the Van Slyke-Folch wet carbon combustion. 1951 20.48
31 A submicrodetermination of glucose. 1949 20.20
32 Protein purification by affinity chromatography. Derivatizations of agarose and polyacrylamide beads. 1970 19.51
33 Sucrose synthesis from acetate in the germinating castor bean: kinetics and pathway. 1961 19.30
34 Codon selection in yeast. 1982 19.13
35 A modified colorimetric method for the estimation of N-acetylamino sugars. 1955 18.78
36 A simplified method for the estimation of total cholesterol in serum and demonstration of its specificity. 1952 18.27
37 Evidence for two functional gal promoters in intact Escherichia coli cells. 1981 17.42
38 The biochemical basis of phagocytosis. I. Metabolic changes during the ingestion of particles by polymorphonuclear leukocytes. 1959 17.39
39 The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. 1998 17.36
40 Method for the determination of hexosamines in tissues. 1953 17.27
41 A new spectrophotometric method for the detection and determination of keto sugars and trioses. 1951 17.26
42 A microchemical determination of desoxyribonucleic acid. 1952 17.00
43 Uptake of radioactive alanine in vitro into the proteins of rat liver fractions. 1952 16.86
44 Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters. 1982 16.71
45 The occurrence and determination of delta-amino-levulinic acid and porphobilinogen in urine. 1956 16.55
46 A microcolorimetric method for the determination of inorganic phosphorus. 1953 16.50
47 The oxidation of ribonuclease with performic acid. 1956 16.39
48 Determination of serum proteins by means of the biuret reaction. 1949 16.38
49 Molecular weight determination of protein-dodecyl sulfate complexes by gel electrophoresis in a discontinuous buffer system. 1971 16.34
50 A gas-liquid solid phase peptide and protein sequenator. 1981 15.73
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