| Rank |
Title |
Year |
PubWeight™‹?› |
|
1
|
Penetration through the gram-negative cell wall: a co-determinant of the efficacy of beta-lactam antibiotics.
|
1979
|
2.07
|
|
2
|
The influence of temperature of ingested fluid on stomach emptying time.
|
1977
|
1.53
|
|
3
|
[First experiences with BS 100-141, a new antihypertensive substance].
|
1976
|
1.51
|
|
4
|
Antihypertensive effect of N-amidino-2-(2,6-dichlorophenyl) acetamide hydrochloride. A double-blind cross-over trial versus clonidine.
|
1978
|
1.50
|
|
5
|
Assessment and treatment of abstinence in the infant of the drug-dependent mother.
|
1975
|
1.49
|
|
6
|
Long-term follow-up study of gastric cancer patients treated with surgery and adjuvant chemotherapy with mitomycin C.
|
1978
|
1.20
|
|
7
|
Comparative pharmacokinetic investigations with tritium-labeled ergot alkaloids after oral and intravenous administration man.
|
1977
|
1.19
|
|
8
|
Clofibrate and enzymatic induction in man.
|
1978
|
1.18
|
|
9
|
Immune reactions associated with practolol therapy.
|
1978
|
1.12
|
|
10
|
Pharmacological evaluation of YC-93, a new vasodilator, in healthy volunteers.
|
1977
|
1.10
|
|
11
|
The relative potencies and beta2-selectivities of intravenous rimiterol, salbutamol and isoprenaline in asthmatic patients.
|
1975
|
1.04
|
|
12
|
Pharmacokinetics and therapeutic efficacy of metronidazole at different dosages.
|
1978
|
1.03
|
|
13
|
Effects of sex hormones on oncogenesis in rat urinary bladder by N-butyl-N-(4-hydroxybutyl)-nitrosamine.
|
1977
|
1.00
|
|
14
|
Deaths in connection with chlormethiazole (heminevrin) therapy.
|
1976
|
1.00
|
|
15
|
The pharmacokinetics of the oral cephalosporins cefaclor, cephradine and cephalexin.
|
1979
|
0.99
|
|
16
|
A clinical trial with nomifensin, a new antidepressant drug.
|
1975
|
0.98
|
|
17
|
[The propagation of aminoglycoside transferases in gram negative bacteria].
|
1979
|
0.97
|
|
18
|
The pharmacokinetics of dihydroergotamine in the beagle.
|
1978
|
0.97
|
|
19
|
Cerebrovascular effects of YC-93, a new vasodilator, in dogs, monkeys and human patients.
|
1979
|
0.97
|
|
20
|
Antihypertensive effect of trimepranol, a new beta-blocking agent.
|
1978
|
0.96
|
|
21
|
Assessment of beta-blocking activity of trimepranol in man.
|
1978
|
0.96
|
|
22
|
Renal function following a single dose of pindolol in hypertensive patients with varying degrees of impairment of renal function.
|
1977
|
0.95
|
|
23
|
Intramuscular absorption of dihydroergotamine in man.
|
1978
|
0.95
|
|
24
|
Hormonal regulation of drug metabolism during pregnancy.
|
1975
|
0.94
|
|
25
|
Plasma concentrations of diazepam and its metabolites after peroral, intramuscular, and rectal administration. Correlation between plasma concentration and sedatory effect of diazepam.
|
1975
|
0.93
|
|
26
|
Experimentally induced pain: measurement of pain threshold and pain tolerance using a new apparatus for electrical stimulation of the skin.
|
1977
|
0.93
|
|
27
|
Comparison of renal excretion of chloramphenicol in patients with chronic pyelonephritis, glomerulonephritis and polycystic kidneys.
|
1976
|
0.92
|
|
28
|
Some aspects of pharmacokinetic and biotransformation differences in humans and mammal animals.
|
1978
|
0.92
|
|
29
|
Interindividual differences of protein binding in man.
|
1979
|
0.91
|
|
30
|
A study of practolol elimination in all grades of chronic renal failure.
|
1975
|
0.90
|
|
31
|
Effects of tetrahydrocannabinol on arterial and intraocular hypertension.
|
1979
|
0.90
|
|
32
|
Factors affecting the bioavailability of phenytoin.
|
1977
|
0.90
|
|
33
|
Urinary excretion of drugs in chronic renal impairment with respect to changes their tubular handling by residual nephrons.
|
1976
|
0.90
|
|
34
|
Increasing threat to man as a result of frequently uncontrolled and widespread use of various drugs.
|
1975
|
0.90
|
|
35
|
The effect of alternate-day prednisone therapy on cortisol secretion rate in corticosteroid-dependent asthmatics.
|
1977
|
0.89
|
|
36
|
Beta-lactamases.
|
1979
|
0.89
|
|
37
|
Serum growth hormone, serum immunoreactive insulin and blood glucose response to oral and intravenous diazepam in man.
|
1975
|
0.88
|
|
38
|
Dissociation between clinical and exercise responsiveness to beta-blockade in angina.
|
1978
|
0.88
|
|
39
|
Effect of long-term alcohol consumption on the half-life of tetracycline and doxycycline in man.
|
1976
|
0.88
|
|
40
|
Effects of tolmetin, paracetamol, and of two combinations of tolmetin and paracetamol as compared to placebo on experimentally induced pain. A double blind study.
|
1979
|
0.88
|
|
41
|
Results obtained with fractionated ifosfamide massive-dose treatment in generalized malignant tumours.
|
1976
|
0.87
|
|
42
|
Respiratory and circulatory interactions of salbutamol and theophyllamine in asthmatic patients.
|
1979
|
0.87
|
|
43
|
Gentamicin pharmacokinetics during hemodialysis in patients suffering from chronic renal failure.
|
1977
|
0.87
|
|
44
|
Prediction of psychotropic properties of lisuride hydrogen maleate by quantitative pharmaco-electroencephalogram.
|
1975
|
0.86
|
|
45
|
Dosage monitoring through measurement of serum level--a task of clinical pharmacology.
|
1978
|
0.86
|
|
46
|
A clinical trial of intravenous bleomycin in the treatment of brain tumors.
|
1975
|
0.86
|
|
47
|
Investigation on the serum and lung tissue level of rifampicin in man.
|
1976
|
0.86
|
|
48
|
Comparative investigation of the respiratory and cardiovascular effect of mepindolol, propranolol and pindolol in asthmatic patients.
|
1978
|
0.86
|
|
49
|
Production of endogenous D-glucaric acid and oxidative N-demethylation of amidopyrine in man: lack of correlation.
|
1979
|
0.86
|
|
50
|
[Elimination kinetics of phenprocoumon (Marcumar) in liver cirrhosis and after premedication with phenobarbital].
|
1976
|
0.86
|