Eicosanoids

Journal PubWeight™ 73.90‹?›

Top papers

Rank Title Year PubWeight™‹?›
1 Effect of the thromboxane receptor antagonist, BM 13.505, on the sequelae of endotoxemia in the conscious rat. 1988 1.38
2 Biosynthesis and interaction of endothelium-derived vasoactive mediators. 1991 1.21
3 The neutrophil and leukotrienes--role in health and disease. 1990 1.17
4 Prostaglandin J2--anti-tumour and anti-viral activities and the mechanisms involved. 1990 1.04
5 CP-66,248, a new anti-inflammatory agent, is a potent inhibitor of leukotriene B4 and prostanoid synthesis in human polymorphonuclear leucocytes in vitro. 1988 1.02
6 Structure elucidation of oxygenated lipids in human atherosclerotic lesions. 1992 0.98
7 PGD2 and its mimetic ZK 110.841 are potent inhibitors of receptor-mediated activation of human neutrophils. 1991 0.94
8 Hepoxilin A3 increases vascular permeability in the rat skin. 1991 0.94
9 Immunoquantitation of thromboxane synthase in human tissues. 1990 0.91
10 Formation of ketodienoic fatty acids by the pure pea lipoxygenase-1. 1991 0.87
11 Kinetic analysis of a TxA2 receptor antagonist. Evidence for the existence of an uptake system. 1990 0.86
12 Arachidonate 15-lipoxygenase; characteristics and potential biological significance. 1991 0.86
13 Formation of lipoxins and leukotrienes by human alveolar macrophages incubated with 15(S)-HETE: a model for cellular cooperation between macrophages and airway epithelial cells. 1992 0.86
14 The physiology and pathophysiology of eicosanoids in the skin. 1988 0.86
15 Omega-3 polyunsaturated fatty acids augment endothelium-dependent vasorelaxation by enhanced release of EDRF and vasodilator prostaglandins. 1991 0.85
16 Nitrovasodilator-induced inhibition of LTB4 release from human PMN may be mediated by cyclic GMP. 1990 0.83
17 Simvastatin reduces platelet thromboxane formation and restores normal platelet sensitivity against prostacyclin in type IIa hypercholesterolemia. 1989 0.83
18 Effect of the prostacyclin analogue iloprost on K+ permeability in the smooth muscle cells of the canine carotid artery. 1989 0.82
19 Differences of metabolism of prostaglandin E2 and F2 alpha by decidual stromal cells and macrophages in culture. 1991 0.82
20 A Calluna vulgaris extract 5-lipoxygenase inhibitor shows potent antiproliferative effects on human leukemia HL-60 cells. 1992 0.82
21 Adherence of leucocytes to electrically damaged venules in vivo. Effects of iloprost, PGE1, indomethacin, forskolin, BW 755 C, sulotroban, hirudin, and thrombocytopenia. 1988 0.81
22 Antiplatelet, antineutrophil and vasodilating properties of 13,14-dihydro-PGE1 (PGE0)--an in vivo metabolite of PGE1 in man. 1991 0.81
23 Effects of defibrotide on prostacyclin release from isolated rabbit kidneys and protection from post-ischemic acute renal failure in vivo. 1991 0.81
24 Prostaglandin receptors in the cardiovascular system: potential selectivity from receptor subtypes or modified responsiveness. 1989 0.80
25 Priming mechanisms and induction of heat shock proteins in human polymorphonuclear granulocytes induced by eicosanoids and cytokines. 1992 0.80
26 Increased concentrations of eicosanoids and platelet-activating factor in menstrual blood from women with primary dysmenorrhea. 1991 0.80
27 Effects of prostaglandin E2 and cyclic AMP on uptake of immunoglobulin G complexes by cultured macrophages. 1992 0.80
28 CD 18 monoclonal antibody inhibits neutrophil diapedesis in the murine dermis induced by leukotriene B4 and 12(R)-hydroxyeicosatetraenoic acid. 1990 0.80
29 ACE-inhibition, kinins, and vascular PGI2 synthesis. 1992 0.80
30 Interaction of 5-HETE, 12-HETE, 15-HETE and 5,12-diHETE at the human platelet thromboxane A2/prostaglandin H2 receptor. 1990 0.80
31 An abnormality of arachidonic acid metabolism is not a generalized phenomenon in patients with aspirin-induced asthma. 1988 0.80
32 Prostaglandin synthetase inhibition and formation of lipoxygenase products in immunologically challenged normal human lung parenchyma. 1988 0.80
33 Sulfhydryl reagents as model substances for eicosanoid research. 1988 0.80
34 Prostacyclin and the mechanism of action of defibrotide. 1989 0.79
35 Endothelium-dependent relaxation of rat aortic rings by leukotriene D4: importance of the magnitude of preload. 1989 0.79
36 Leukotriene and prostaglandin production after infusion of tumour necrosis factor in man. 1991 0.79
37 Cyclic AMP-mediated inhibition of cell growth by prostaglandin D2 in a fibroblastic cell line (EBTr). 1990 0.79
38 Prostaglandin levels in the rat resting gastric wall and enhancement of prostaglandin E2 generation after administration of mild hyperosmotic saline solution into the gastric lumen. 1990 0.79
39 Problems in production of prostaglandin D2-specific antibody. 1988 0.78
40 Prolactin secretion in anterior pituitary cells: effect of eicosanoids. 1992 0.78
41 NADPH-dependent formation of 15- and 12-hydroxyeicosatrienoic acid from arachidonic acid by rat epidermal microsomes. 1991 0.78
42 Lipoxin A4 elevates cytosolic calcium in human neutrophils. 1991 0.78
43 Stimulation of the 15-lipoxygenase in activated polymorphonuclear neutrophils. Influence of lipoxygenase inhibitors and hydroxyeicosatetraenoic acid derivatives. 1990 0.78
44 Adrenaline stimulates thromboxane and inhibits leukotriene synthesis in man. 1992 0.78
45 Comparison of urinary leukotriene E4 and 16-carboxytetranordihydro leukotriene E4 excretion in allergic asthmatics after inhaled antigen. 1990 0.78
46 Metabolism of absorbed glucose in mouse jejunum: influence of arachidonic acid, non-steroidal anti-inflammatory drugs and eicosanoids. 1992 0.78
47 The role of the epidermal 12-hydroxyeicosatetraenoic acid receptor in the skin. 1992 0.78
48 Membranes exert indirect negative control on phospholipase A2 in human placenta. 1991 0.78
49 Effect of prostaglandin E2 or prostaglandin synthesis inhibitors on human gonadotrophins and prolactin. 1992 0.78
50 Increased prostacyclin biosynthesis in patients with osteoid osteoma. 1991 0.78
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