Published in Cell Mol Neurobiol on February 01, 1999
Forced exercise enhances functional recovery after focal cerebral ischemia in spontaneously hypertensive rats. Brain Sci (2012) 0.91
Normobaric hyperoxia delays and attenuates early nitric oxide production in focal cerebral ischemic rats. Brain Res (2010) 0.87
Age-related changes of NADPH-diaphorase positivity in the rat rostral migratory stream. Cell Mol Neurobiol (2005) 0.81
Protective Role of Arginase II in Cerebral Ischemia and Excitotoxicity. J Neurol Neurosci (2016) 0.75
Spatiotemporal alterations of the NO/NOS neuronal pools following transient abdominal aorta occlusion: morphological and biochemical studies in the rabbit. Cell Mol Neurobiol (2006) 0.75
Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci U S A (1990) 16.34
Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme. Proc Natl Acad Sci U S A (1990) 10.40
Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase. Nature (1991) 8.41
A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds. Nature (1993) 8.29
Nitric oxide stimulates auto-ADP-ribosylation of glyceraldehyde-3-phosphate dehydrogenase. Proc Natl Acad Sci U S A (1992) 8.24
Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. Stroke (1986) 8.23
Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum. Proc Natl Acad Sci U S A (1989) 6.08
Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures. Proc Natl Acad Sci U S A (1991) 5.70
Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase. Science (1994) 5.15
Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity. Science (1994) 3.86
Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J Neurochem (1984) 3.39
Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-L-arginine. J Cereb Blood Flow Metab (1996) 2.78
Nitric oxide synthase protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with NADPH diaphorase. Neuron (1991) 2.60
Gases as biological messengers: nitric oxide and carbon monoxide in the brain. J Neurosci (1994) 2.25
Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists. J Neurosci (1988) 2.14
Nitric oxide regulates mitochondrial respiration and cell functions by inhibiting cytochrome oxidase. FEBS Lett (1995) 2.01
Nitric oxide mediates neuronal death after focal cerebral ischemia in the mouse. Eur J Pharmacol (1991) 1.85
Nitric oxide measured by a porphyrinic microsensor in rat brain after transient middle cerebral artery occlusion. J Cereb Blood Flow Metab (1993) 1.63
Inducible nitric oxide synthase gene expression in brain following cerebral ischemia. J Cereb Blood Flow Metab (1995) 1.31
Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity. Proc Natl Acad Sci U S A (1993) 1.31
Inducible nitric oxide synthase gene expression in vascular cells after transient focal cerebral ischemia. Stroke (1996) 1.30
Inhibition of inducible nitric oxide synthase ameliorates cerebral ischemic damage. Am J Physiol (1995) 1.27
Free radicals and brain damage. Cerebrovasc Brain Metab Rev (1989) 1.18
The NOS inhibitor, 7-nitroindazole, decreases focal infarct volume but not the response to topical acetylcholine in pial vessels. J Cereb Blood Flow Metab (1994) 1.17
Neuronal (type I) nitric oxide synthase regulates nuclear factor kappaB activity and immunologic (type II) nitric oxide synthase expression. Proc Natl Acad Sci U S A (1997) 1.15
The neuroprotective effect of a nitric oxide inhibitor in a rat model of focal cerebral ischaemia. Br J Pharmacol (1992) 1.10
L-arginine decreases infarct size caused by middle cerebral arterial occlusion in SHR. Am J Physiol (1992) 1.09
Marked induction of calcium-independent nitric oxide synthase activity after focal cerebral ischemia. J Cereb Blood Flow Metab (1995) 1.08
ARL 17477, a potent and selective neuronal NOS inhibitor decreases infarct volume after transient middle cerebral artery occlusion in rats. J Cereb Blood Flow Metab (1996) 1.01
Nitric oxide synthesis and regional cerebral blood flow responses to hypercapnia and hypoxia in the rat. J Cereb Blood Flow Metab (1993) 1.01
Effect of nitric oxide blockade by NG-nitro-L-arginine on cerebral blood flow response to changes in carbon dioxide tension. J Cereb Blood Flow Metab (1992) 1.00
A new model of temporary focal neocortical ischemia in the rat. Stroke (1992) 0.97
Cerebral endothelial nitric oxide synthase expression after focal cerebral ischemia in rats. Stroke (1993) 0.94
Nitric oxide (NO) is involved in increased cerebral cortical blood flow following stimulation of the nucleus basalis of Meynert in anesthetized rats. Neurosci Lett (1992) 0.93
Blockade of nitric oxide formation by N omega-nitro-L-arginine mitigates ischemic brain edema and subsequent cerebral infarction in rats. Neurosci Lett (1992) 0.91
Cerebroprotective effects of aminoguanidine in a rodent model of stroke. Stroke (1996) 0.89
Upregulation of neuronal nitric oxide synthase and mRNA, and selective sparing of nitric oxide synthase-containing neurons after focal cerebral ischemia in rat. Brain Res (1994) 0.86
Inhibition of nitric oxide synthesis increases focal ischemic infarction in rat. J Cereb Blood Flow Metab (1992) 0.86
The effect of nitric oxide synthase inhibition on infarct volume after reversible focal cerebral ischemia in conscious rats. Stroke (1993) 0.86
Anti-ischaemic efficacy of a nitric oxide synthase inhibitor and a N-methyl-D-aspartate receptor antagonist in models of transient and permanent focal cerebral ischaemia. Br J Pharmacol (1994) 0.84
Nitroprusside improves blood flow and reduces brain damage after focal ischemia. Neuroreport (1993) 0.81
Elevation of plasma nitric oxide end products during focal cerebral ischemia and reperfusion in the rat. J Cereb Blood Flow Metab (1994) 0.80
Ca2+-activated mechanisms in cell killing. Drug Metab Rev (1989) 0.79
Temporal profiles of Ca2+/calmodulin-dependent and -independent nitric oxide synthase activity in the rat brain microvessels following cerebral ischemia. Acta Neurochir Suppl (Wien) (1994) 0.78
The neuroprotective effect of a potent and selective inhibitor of type I NOS (L-MIN) in a rat model of focal cerebral ischaemia. Neuroreport (1995) 0.78
Neuroprotective efficacy of N omega-nitro-L-arginine after focal cerebral ischemia in the mouse and inhibition of cortical nitric oxide synthase. Eur J Pharmacol (1994) 0.78
Time dependence of effect of nitric oxide synthase inhibition on cerebral ischemic damage. J Cereb Blood Flow Metab (1995) 0.77
N omega-nitro-L-arginine attenuates early ischemic neuronal damage of prolonged focal cerebral ischemia and recirculation in rats. Neurol Res (1997) 0.75
Effect of a new immunosuppressive agent, FK 506, on heterotopic cardiac allotransplantation in the rat. Transplant Proc (1987) 12.04
Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms. Endocrinology (1990) 6.34
Cyclosporine induces cancer progression by a cell-autonomous mechanism. Nature (1999) 3.93
Molecular diversity of the NMDA receptor channel. Nature (1992) 3.76
Choice in the repeated-gambles experiment. J Exp Anal Behav (1988) 3.57
Increased insulin sensitivity and hypoglycaemia in mice lacking the p85 alpha subunit of phosphoinositide 3-kinase. Nat Genet (1999) 2.81
Nonsense mutation of glucokinase gene in late-onset non-insulin-dependent diabetes mellitus. Lancet (1992) 2.71
A prolactin-releasing peptide in the brain. Nature (1998) 2.43
Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family. J Biol Chem (1998) 2.42
Evaluation of liver tumors using fluorine-18-fluorodeoxyglucose PET: characterization of tumor and assessment of effect of treatment. J Nucl Med (1992) 2.30
Functional characterization of a heteromeric NMDA receptor channel expressed from cloned cDNAs. Nature (1992) 2.18
Studies of the induction and maintenance of long-term graft acceptance by treatment with FK506 in heterotopic cardiac allotransplantation in rats. Transplantation (1987) 2.15
Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets. Diabetologia (1993) 2.11
Risk of bile duct carcinogenesis after excision of extrahepatic bile ducts in pancreaticobiliary maljunction. Surgery (1999) 2.09
Reciprocal role of ERK and NF-kappaB pathways in survival and activation of osteoclasts. J Cell Biol (2000) 2.04
Effects of combination treatment with FK506 and cyclosporine on survival time and vascular changes in renal-allograft-recipient dogs. Transplantation (1989) 2.03
The structure and function of p55PIK reveal a new regulatory subunit for phosphatidylinositol 3-kinase. Mol Cell Biol (1995) 1.97
Reconstitution of catecholamine-stimulated guanosinetriphosphatase activity. Biochemistry (1983) 1.87
Enhanced myosin light chain phosphorylations as a central mechanism for coronary artery spasm in a swine model with interleukin-1beta. Circulation (1997) 1.83
The coxsackievirus-adenovirus receptor protein as a cell adhesion molecule in the developing mouse brain. Brain Res Mol Brain Res (2000) 1.80
Ebselen in acute ischemic stroke: a placebo-controlled, double-blind clinical trial. Ebselen Study Group. Stroke (1998) 1.79
RGS8 accelerates G-protein-mediated modulation of K+ currents. Nature (1997) 1.73
Ethanol opens G-protein-activated inwardly rectifying K+ channels. Nat Neurosci (1999) 1.66
Cloning of cDNAs encoding two isoforms of 68-kDa type I phosphatidylinositol-4-phosphate 5-kinase. J Biol Chem (1996) 1.59
Studies with antipeptide antibody suggest the presence of at least two types of glucose transporter in rat brain and adipocyte. J Biol Chem (1988) 1.59
Frequent p53 accumulation in the chronically sun-exposed epidermis and clonal expansion of p53 mutant cells in the epidermis adjacent to basal cell carcinoma. J Invest Dermatol (1995) 1.55
Resistance of germfree rats to indomethacin-induced intestinal lesions. Prostaglandins (1977) 1.53
Massive actin polymerization induced by phosphatidylinositol-4-phosphate 5-kinase in vivo. J Biol Chem (1997) 1.51
Rho-kinase-mediated pathway induces enhanced myosin light chain phosphorylations in a swine model of coronary artery spasm. Cardiovasc Res (1999) 1.48
A novel 55-kDa regulatory subunit for phosphatidylinositol 3-kinase structurally similar to p55PIK Is generated by alternative splicing of the p85alpha gene. J Biol Chem (1996) 1.47
Screening of patients with maternally transmitted diabetes for mitochondrial gene mutations in the tRNA[Leu(UUR)] region. Diabet Med (1997) 1.46
Effects of staphylococcal enterotoxin B on intestinal transport in the rat. Am J Physiol (1971) 1.45
Naftopidil, a novel alpha1-adrenoceptor antagonist, displays selective inhibition of canine prostatic pressure and high affinity binding to cloned human alpha1-adrenoceptors. Jpn J Pharmacol (1999) 1.41
Overexpression of catalytic subunit p110alpha of phosphatidylinositol 3-kinase increases glucose transport activity with translocation of glucose transporters in 3T3-L1 adipocytes. J Biol Chem (1996) 1.39
Prolongation of canine renal allograft survival by treatment with FK-506. Transplant Proc (1987) 1.38
Copurification of small heat shock protein with alpha B crystallin from human skeletal muscle. J Biol Chem (1992) 1.37
p85alpha gene generates three isoforms of regulatory subunit for phosphatidylinositol 3-kinase (PI 3-Kinase), p50alpha, p55alpha, and p85alpha, with different PI 3-kinase activity elevating responses to insulin. J Biol Chem (1997) 1.37
Altered expression levels and impaired steps in the pathway to phosphatidylinositol 3-kinase activation via insulin receptor substrates 1 and 2 in Zucker fatty rats. Diabetes (1998) 1.37
Maximizing present value: A model to explain why moderate response rates obtain on variable-interval schedules. J Exp Anal Behav (1988) 1.33
Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5'-phosphatase catalytic activity. Mol Cell Biol (2001) 1.32
T-1095, an inhibitor of renal Na+-glucose cotransporters, may provide a novel approach to treating diabetes. Diabetes (1999) 1.32
14-3-3 protein binds to insulin receptor substrate-1, one of the binding sites of which is in the phosphotyrosine binding domain. J Biol Chem (1997) 1.32
Molecular cloning of a mouse G-protein-activated K+ channel (mGIRK1) and distinct distributions of three GIRK (GIRK1, 2 and 3) mRNAs in mouse brain. Biochem Biophys Res Commun (1995) 1.32
C-terminal truncated glucose transporter is locked into an inward-facing form without transport activity. Nature (1990) 1.27
Human blood platelet 3': 5'-cyclic nucleotide phosphodiesterase. Isolation of low-Km and high-Km phosphodiesterase. Biochim Biophys Acta (1976) 1.26
Purification and characterization of a 20-kDa protein that is highly homologous to alpha B crystallin. J Biol Chem (1994) 1.25
STAT3 inhibitor WP1066 as a novel therapeutic agent for renal cell carcinoma. Br J Cancer (2010) 1.25
Pharmacological profile of hydroxy fasudil as a selective rho kinase inhibitor on ischemic brain damage. Life Sci (2001) 1.25
Successful combined operation for mitral stenosis and atrial fibrillation. Ann Thorac Surg (1993) 1.24
Reconstitution of catecholamine-stimulated binding of guanosine 5'-O-(3-thiotriphosphate) to the stimulatory GTP-binding protein of adenylate cyclase. Biochemistry (1984) 1.24
Intraductal papillary mucinous tumors of the pancreas. Am J Surg (1999) 1.23
Gelation of Limulus amoebocyte lysate by an antitumor (1 leads to 3)-beta-D-glucan. Biochem Biophys Res Commun (1981) 1.23
Dexamethasone-induced insulin resistance in 3T3-L1 adipocytes is due to inhibition of glucose transport rather than insulin signal transduction. Diabetes (2000) 1.22
Metabolism of vitamin D in animals. V. Isolation of vitamin D sulfate from mammalian milk. J Vitaminol (Kyoto) (1967) 1.21
Purification and characterization of recombinant human interleukin-2 produced in Escherichia coli. Biochem Biophys Res Commun (1985) 1.21
Brain tumors induced with Rous sarcoma virus, Schmidt-Ruppin strain. I. Induction of brain tumors in adult mice with Rous chicken sarcoma cells. Jpn J Exp Med (1967) 1.19
The Fyn tyrosine kinase binds Irs-1 and forms a distinct signaling complex during insulin stimulation. J Biol Chem (1996) 1.18
Effects of rabeprazole, lansoprazole and omeprazole on intragastric pH in CYP2C19 extensive metabolizers. Aliment Pharmacol Ther (2002) 1.18
Protective immune responses induced by secretion of a chimeric soluble protein from a recombinant Mycobacterium bovis bacillus Calmette-Guérin vector candidate vaccine for human immunodeficiency virus type 1 in small animals. Proc Natl Acad Sci U S A (1995) 1.17
Defect in negative selection in lpr donor-derived T cells differentiating in non-lpr host thymus. J Exp Med (1991) 1.16
Detection of Chlamydia trachomatis in vaginal specimens from female commercial sex workers using a new improved enzyme immunoassay. Sex Transm Infect (1998) 1.16
Long-term inhibition of Rho-kinase induces a regression of arteriosclerotic coronary lesions in a porcine model in vivo. Cardiovasc Res (2001) 1.15
Vasodilatory action of HA1004 [N-(2-guanidinoethyl)-5-isoquinolinesulfonamide], a novel calcium antagonist with no effect on cardiac function. J Pharmacol Exp Ther (1984) 1.14
Insulin prevents cardiomyocytes from oxidative stress-induced apoptosis through activation of PI3 kinase/Akt. Circulation (2000) 1.14
Two glucose transporter isoforms are sorted differentially and are expressed in distinct cellular compartments. Biochem J (1992) 1.13
Identification of inosine and hypoxanthine as endogenous ligands for the brain benzodiazepine-binding sites. Proc Natl Acad Sci U S A (1979) 1.13
Expression of vascular endothelial growth factor in capillary hemangioblastoma. Biochem Biophys Res Commun (1993) 1.12
Activation of the inhibitory GTP-binding protein of adenylate cyclase, Gi, by beta-adrenergic receptors in reconstituted phospholipid vesicles. J Biol Chem (1984) 1.12
Uncoupling of gamma-aminobutyric acid B receptors from GTP-binding proteins by N-ethylmaleimide: effect of N-ethylmaleimide on purified GTP-binding proteins. Mol Pharmacol (1986) 1.11
AMP deaminase isozymes in human tissues. Biochim Biophys Acta (1982) 1.11
Modulation of the stress-induced synthesis of hsp27 and alpha B-crystallin by cyclic AMP in C6 rat glioma cells. J Neurochem (1996) 1.11
Regeneration of periodontal tissues by basic fibroblast growth factor. J Periodontal Res (1999) 1.11
An immunoperoxidase study on herpes simplex virus encephalitis. J Neuropathol Exp Neurol (1979) 1.10
Studies on FK506 in experimental organ transplantation. Transplant Proc (1988) 1.10
Neuroprotective effect of an antioxidant, ebselen, in patients with delayed neurological deficits after aneurysmal subarachnoid hemorrhage. Neurosurgery (1998) 1.09
Effects of basic fibroblast growth factor on human periodontal ligament cells. J Periodontal Res (1997) 1.09
ABCB1 C3435T polymorphism influences methotrexate sensitivity in rheumatoid arthritis patients. Clin Exp Rheumatol (2006) 1.08
MKK6/3 and p38 MAPK pathway activation is not necessary for insulin-induced glucose uptake but regulates glucose transporter expression. J Biol Chem (2001) 1.07
Induction of CD16+ CD56bright NK cells with antitumour cytotoxicity not only from CD16- CD56bright NK Cells but also from CD16- CD56dim NK cells. Scand J Immunol (2007) 1.07
Identification and characterization of a novel inositol polyphosphate 5-phosphatase. J Biol Chem (2000) 1.06
Prolongation of rat heart allograft survival by 15-deoxyspergualin. J Antibiot (Tokyo) (1987) 1.05
Small intestinal perforation in Wegener's granulomatosis. J Rheumatol (1989) 1.05
Effect of transient ischemia on free fatty acids and phospholipids in the gerbil brain. Lipid peroxidation as a possible cause of postischemic injury. J Neurosurg (1980) 1.05
Characterization of interactions between transducin alpha/beta gamma-subunits and lipid membranes. J Biol Chem (1994) 1.05
Neutral endopeptidase inhibits neuropeptide-mediated transactivation of the insulin-like growth factor receptor-Akt cell survival pathway. Cancer Res (2001) 1.04
Mechanism of action of a novel antivasospasm drug, HA1077. J Pharmacol Exp Ther (1987) 1.04
Cloning of a novel murine gene Sfmbt, Scm-related gene containing four mbt domains, structurally belonging to the Polycomb group of genes. Gene (2000) 1.04
Cloning and increased expression with fructose feeding of rat jejunal GLUT5. Endocrinology (1993) 1.04
Effects of vasopressin and oxytocin on canine cerebral circulation in vivo. J Neurosurg (1992) 1.04
A new model of cerebral microthrombosis in rats and the neuroprotective effect of a Rho-kinase inhibitor. Stroke (2000) 1.03
A novel CD3-J11d+ subset of CD4+CD8- cells repopulating thymus in radiation bone marrow chimeras. Eur J Immunol (1989) 1.03
Regulation of phosphoinositide metabolism, Akt phosphorylation, and glucose transport by PTEN (phosphatase and tensin homolog deleted on chromosome 10) in 3T3-L1 adipocytes. Mol Endocrinol (2001) 1.03
Clinical and experimental studies of acute pancreatitis after renal transplantation. Transplant Proc (1992) 1.03
Novel small GTPase M-Ras participates in reorganization of actin cytoskeleton. Oncogene (1997) 1.03
High levels of nervous system-specific proteins in cerebrospinal fluid in patients with early stage Creutzfeldt-Jakob disease. Clin Chim Acta (1992) 1.02
Oxidative stress induces insulin resistance by activating the nuclear factor-kappa B pathway and disrupting normal subcellular distribution of phosphatidylinositol 3-kinase. Diabetologia (2004) 1.02
Increased liver glucose-transporter protein and mRNA in streptozocin-induced diabetic rats. Diabetes (1990) 1.02
[Surgical resection of adrenal carcinoma extending into the vena cava, right atrium and ventricle: case report and review of the literature]. Nihon Geka Gakkai Zasshi (1987) 1.02