Published in Nature on May 20, 1999
The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation. Nat Rev Genet (2010) 4.46
Quantitative proteomic analysis of distinct mammalian Mediator complexes using normalized spectral abundance factors. Proc Natl Acad Sci U S A (2006) 3.71
Mediator links epigenetic silencing of neuronal gene expression with x-linked mental retardation. Mol Cell (2008) 3.53
The human Mediator complex: a versatile, genome-wide regulator of transcription. Trends Biochem Sci (2010) 3.38
Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation. Genes Dev (2002) 2.02
A tissue-specific coactivator of steroid receptors, identified in a functional genetic screen. Mol Cell Biol (2000) 1.99
Requirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAF(II)s. Mol Cell Biol (2002) 1.86
Coactivator cross-talk specifies transcriptional output. Genes Dev (2006) 1.79
Structural organization of yeast and mammalian mediator complexes. Proc Natl Acad Sci U S A (2000) 1.76
The activator-recruited cofactor/Mediator coactivator subunit ARC92 is a functionally important target of the VP16 transcriptional activator. Proc Natl Acad Sci U S A (2004) 1.70
Novel critical role of a human Mediator complex for basal RNA polymerase II transcription. EMBO Rep (2001) 1.67
Temporal recruitment of the mSin3A-histone deacetylase corepressor complex to the ETS domain transcription factor Elk-1. Mol Cell Biol (2001) 1.65
The Mediator complex and transcription regulation. Crit Rev Biochem Mol Biol (2013) 1.64
Mediator modulates Gli3-dependent Sonic hedgehog signaling. Mol Cell Biol (2006) 1.58
Principal role of TRAP/mediator and SWI/SNF complexes in Kaposi's sarcoma-associated herpesvirus RTA-mediated lytic reactivation. Mol Cell Biol (2003) 1.53
Intrinsic structural disorder in adenovirus E1A: a viral molecular hub linking multiple diverse processes. J Virol (2008) 1.53
Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor. Genes Dev (2007) 1.49
TFIID and human mediator coactivator complexes assemble cooperatively on promoter DNA. Genes Dev (2002) 1.45
The DRIP complex and SRC-1/p160 coactivators share similar nuclear receptor binding determinants but constitute functionally distinct complexes. Mol Cell Biol (2000) 1.38
The TRAP100 component of the TRAP/Mediator complex is essential in broad transcriptional events and development. EMBO J (2002) 1.38
Interaction of Bunyamwera Orthobunyavirus NSs protein with mediator protein MED8: a mechanism for inhibiting the interferon response. J Virol (2006) 1.36
Identification of a transcriptionally active peroxisome proliferator-activated receptor alpha -interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator. Proc Natl Acad Sci U S A (2002) 1.36
Drosophila homologs of transcriptional mediator complex subunits are required for adult cell and segment identity specification. Genes Dev (2000) 1.34
TRAP/SMCC/mediator-dependent transcriptional activation from DNA and chromatin templates by orphan nuclear receptor hepatocyte nuclear factor 4. Mol Cell Biol (2002) 1.31
Mediator coordinates PIC assembly with recruitment of CHD1. Genes Dev (2011) 1.28
Activation domain-mediator interactions promote transcription preinitiation complex assembly on promoter DNA. Proc Natl Acad Sci U S A (2003) 1.28
Dysregulation of the basal RNA polymerase transcription apparatus in cancer. Nat Rev Cancer (2013) 1.26
A role for coactivators and histone acetylation in estrogen receptor alpha-mediated transcription initiation. EMBO J (2001) 1.25
Chromatin-bound mitogen-activated protein kinases transmit dynamic signals in transcription complexes in beta-cells. Proc Natl Acad Sci U S A (2008) 1.23
A C. elegans mediator protein confers regulatory selectivity on lineage-specific expression of a transcription factor gene. Genes Dev (2000) 1.22
Activator-independent functions of the yeast mediator sin4 complex in preinitiation complex formation and transcription reinitiation. Mol Cell Biol (2003) 1.22
Role of metazoan mediator proteins in interferon-responsive transcription. Mol Cell Biol (2003) 1.22
Structure of the VP16 transactivator target in the Mediator. Nat Struct Mol Biol (2011) 1.17
Drosophila Mediator complex is broadly utilized by diverse gene-specific transcription factors at different types of core promoters. Mol Cell Biol (2001) 1.16
Human mediator enhances activator-facilitated recruitment of RNA polymerase II and promoter recognition by TATA-binding protein (TBP) independently of TBP-associated factors. Mol Cell Biol (2003) 1.16
The nuclear hormone receptor coactivator NRC is a pleiotropic modulator affecting growth, development, apoptosis, reproduction, and wound repair. Mol Cell Biol (2004) 1.16
Elk-1 a transcription factor with multiple facets in the brain. Front Neurosci (2011) 1.15
MED19 and MED26 are synergistic functional targets of the RE1 silencing transcription factor in epigenetic silencing of neuronal gene expression. J Biol Chem (2008) 1.13
Mediator-dependent nuclear receptor function. Semin Cell Dev Biol (2011) 1.12
Mediator and p300/CBP-steroid receptor coactivator complexes have distinct roles, but function synergistically, during estrogen receptor alpha-dependent transcription with chromatin templates. Mol Cell Biol (2003) 1.12
Mediator and human disease. Semin Cell Dev Biol (2011) 1.10
Regulation of the 26S proteasome by adenovirus E1A. EMBO J (2000) 1.09
Characterization of mediator complexes from HeLa cell nuclear extract. Mol Cell Biol (2001) 1.09
Adenovirus E1B 55-kilodalton protein is required for both regulation of mRNA export and efficient entry into the late phase of infection in normal human fibroblasts. J Virol (2006) 1.08
Adenovirus type 5 exerts genome-wide control over cellular programs governing proliferation, quiescence, and survival. Genome Biol (2007) 1.07
Comparative sequence analysis of the largest E1A proteins of human and simian adenoviruses. J Virol (2002) 1.05
Analysis of Schizosaccharomyces pombe mediator reveals a set of essential subunits conserved between yeast and metazoan cells. Proc Natl Acad Sci U S A (2001) 1.04
NRC-interacting factor 1 is a novel cotransducer that interacts with and regulates the activity of the nuclear hormone receptor coactivator NRC. Mol Cell Biol (2002) 1.03
Canonical RTK-Ras-ERK signaling and related alternative pathways. WormBook (2013) 1.03
C. elegans EOR-1/PLZF and EOR-2 positively regulate Ras and Wnt signaling and function redundantly with LIN-25 and the SUR-2 Mediator component. Genes Dev (2002) 1.02
In vivo association of adenovirus large E1A protein with the human mediator complex in adenovirus-infected and -transformed cells. J Virol (2002) 1.02
Varicella-zoster virus IE62 protein utilizes the human mediator complex in promoter activation. J Virol (2008) 1.02
Transcriptional control by adenovirus E1A conserved region 3 via p300/CBP. Nucleic Acids Res (2009) 1.01
Roles for APIS and the 20S proteasome in adenovirus E1A-dependent transcription. EMBO J (2006) 1.01
A lin-45 raf enhancer screen identifies eor-1, eor-2 and unusual alleles of Ras pathway genes in Caenorhabditis elegans. Genetics (2002) 1.00
Herpes simplex virus 1 ICP4 forms complexes with TFIID and mediator in virus-infected cells. J Virol (2011) 1.00
The C-terminal domain-phosphorylated IIO form of RNA polymerase II is associated with the transcription repressor NC2 (Dr1/DRAP1) and is required for transcription activation in human nuclear extracts. Proc Natl Acad Sci U S A (2000) 0.99
Caenorhabditis elegans unc-37/groucho interacts genetically with components of the transcriptional mediator complex. Genetics (2002) 0.98
Adenovirus protein VII condenses DNA, represses transcription, and associates with transcriptional activator E1A. J Virol (2004) 0.98
Mediator kinase module and human tumorigenesis. Crit Rev Biochem Mol Biol (2015) 0.98
Walleye dermal sarcoma virus cyclin interacts with components of the mediator complex and the RNA polymerase II holoenzyme. J Virol (2002) 0.97
Robust mRNA transcription in chicken DT40 cells depleted of TAF(II)31 suggests both functional degeneracy and evolutionary divergence. Mol Cell Biol (2000) 0.97
Identification of a second CtBP binding site in adenovirus type 5 E1A conserved region 3. J Virol (2008) 0.96
Nuclear receptor coactivator/coregulator NCoA6(NRC) is a pleiotropic coregulator involved in transcription, cell survival, growth and development. Nucl Recept Signal (2008) 0.95
Caenorhabditis elegans mediator complexes are required for developmental-specific transcriptional activation. Proc Natl Acad Sci U S A (1999) 0.95
Site-specific Srb10-dependent phosphorylation of the yeast Mediator subunit Med2 regulates gene expression from the 2-microm plasmid. Proc Natl Acad Sci U S A (2004) 0.95
Mediator MED23 plays opposing roles in directing smooth muscle cell and adipocyte differentiation. Genes Dev (2012) 0.94
External control of Her2 expression and cancer cell growth by targeting a Ras-linked coactivator. Proc Natl Acad Sci U S A (2002) 0.94
The E4-6/7 protein functionally compensates for the loss of E1A expression in adenovirus infection. J Virol (2000) 0.91
The adenoviral E1B 55-kilodalton protein controls expression of immune response genes but not p53-dependent transcription. J Virol (2009) 0.91
Mediator complex dependent regulation of cardiac development and disease. Genomics Proteomics Bioinformatics (2013) 0.90
Message in a nucleus: signaling to the transcriptional machinery. Curr Opin Genet Dev (2008) 0.89
Activation of the Notch-regulated transcription factor CBF1/RBP-Jkappa through the 13SE1A oncoprotein. Genes Dev (2001) 0.88
The critical protein interactions and structures that elicit growth deregulation in cancer and viral replication. Wiley Interdiscip Rev Syst Biol Med (2010) 0.88
Analysis of differential expression of Mediator subunit genes in Arabidopsis. Plant Signal Behav (2012) 0.88
Requirement of Sur2 for efficient replication of mouse adenovirus type 1. J Virol (2004) 0.87
Heterogeneous nuclear ribonucleoprotein R enhances transcription from the naturally configured c-fos promoter in vitro. J Biol Chem (2009) 0.87
Signal-induced transcriptional activation by Dif requires the dTRAP80 mediator module. Mol Cell Biol (2003) 0.87
Cellular GCN5 is a novel regulator of human adenovirus E1A-conserved region 3 transactivation. J Virol (2012) 0.86
Disordered proteinaceous machines. Chem Rev (2014) 0.86
Dual role of Med12 in PRC1-dependent gene repression and ncRNA-mediated transcriptional activation. Cell Cycle (2016) 0.86
The evolutionarily conserved mediator subunit MDT-15/MED15 links protective innate immune responses and xenobiotic detoxification. PLoS Pathog (2014) 0.84
A shared but complex bridge. Nature (1999) 0.84
Adenovirus L-E1A activates transcription through mediator complex-dependent recruitment of the super elongation complex. J Virol (2013) 0.83
Comparison of E1A CR3-dependent transcriptional activation across six different human adenovirus subgroups. J Virol (2010) 0.82
Poly(ADP-ribose) polymerase 1 is a key regulator of estrogen receptor α-dependent gene transcription. J Biol Chem (2013) 0.82
Activator-mediator binding stabilizes RNA polymerase II orientation within the human mediator-RNA polymerase II-TFIIF assembly. J Mol Biol (2012) 0.81
Drosophila Med6 is required for elevated expression of a large but distinct set of developmentally regulated genes. Mol Cell Biol (2001) 0.81
Caenorhabditis elegans lin-25: a study of its role in multiple cell fate specification events involving Ras and the identification and characterization of evolutionarily conserved domains. Genetics (2000) 0.80
E1A-CR3 interaction-dependent and -independent functions of mSur2 in viral replication of early region 1A mutants of mouse adenovirus type 1. J Virol (2005) 0.80
Evolution of disorder in Mediator complex and its functional relevance. Nucleic Acids Res (2015) 0.79
Requirements for E1A dependent transcription in the yeast Saccharomyces cerevisiae. BMC Mol Biol (2009) 0.79
Transcriptional regulation of the human glycoprotein hormone common alpha subunit gene by cAMP-response-element-binding protein (CREB)-binding protein (CBP)/p300 and p53. Biochem J (2002) 0.78
The Mediator complex subunit MED25 is targeted by the N-terminal transactivation domain of the PEA3 group members. Nucleic Acids Res (2013) 0.78
Proteomic analysis of the herpes simplex virus 1 virion protein 16 transactivator protein in infected cells. Proteomics (2015) 0.77
Small molecule probes to target the human Mediator complex. Isr J Chem (2013) 0.76
The RNA Binding Complexes NF45-NF90 and NF45-NF110 Associate Dynamically with the c-fos Gene and Function as Transcriptional Coactivators. J Biol Chem (2015) 0.76
P-TEFb goes viral. Inside Cell (2015) 0.75
Fusion of the BCL9 HD2 domain to E1A increases the cytopathic effect of an oncolytic adenovirus that targets colon cancer cells. BMC Cancer (2006) 0.75
ETV4 and AP1 transcription factors form multivalent interactions with three sites on the MED25 activator-interacting domain. J Mol Biol (2017) 0.75
Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids. Cell (1977) 61.24
Spliced early mRNAs of simian virus 40. Proc Natl Acad Sci U S A (1978) 18.67
Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs. Cell (1979) 12.83
Structure of the adenovirus 2 early mRNAs. Cell (1978) 10.54
Purification and mapping of specific mRNAs by hybridization-selection and cell-free translation. Proc Natl Acad Sci U S A (1979) 9.94
p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. Cell (1994) 7.05
Analysis of adenovirus transforming proteins from early regions 1A and 1B with antisera to inducible fusion antigens produced in Escherichia coli. J Virol (1984) 6.73
Association of human cyclin E with a periodic G1-S phase protein kinase. Science (1992) 5.98
Adenovirus promoters and E1A transactivation. Annu Rev Genet (1986) 5.86
Resolving the functions of overlapping viral genes by site-specific mutagenesis at a mRNA splice site. Nature (1982) 5.61
Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice. Nature (1994) 5.34
Inhibition of RNA cleavage but not polyadenylation by a point mutation in mRNA 3' consensus sequence AAUAAA. Nature (1983) 5.18
Holo-TFIID supports transcriptional stimulation by diverse activators and from a TATA-less promoter. Genes Dev (1992) 4.85
Transcriptional activation by Sp1 as directed through TATA or initiator: specific requirement for mammalian transcription factor IID. Proc Natl Acad Sci U S A (1990) 4.79
The DNA sequence of human herpesvirus-6: structure, coding content, and genome evolution. Virology (1995) 4.77
Adenovirus E1A activation domain binds the basic repeat in the TATA box transcription factor. Cell (1991) 4.66
Expression of early adenovirus genes requires a viral encoded acidic polypeptide. Proc Natl Acad Sci U S A (1981) 4.42
Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein. Nature (1992) 4.36
Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1. Mol Cell Biol (1997) 4.36
Cloning of a transcriptionally active human TATA binding factor. Science (1990) 4.18
Transcription maps of adenovirus. Methods Enzymol (1980) 3.82
A human RNA polymerase II complex associated with SRB and DNA-repair proteins. Nature (1996) 3.50
A human RNA polymerase II complex containing factors that modify chromatin structure. Mol Cell Biol (1998) 3.45
Canopy nitrogen, carbon assimilation, and albedo in temperate and boreal forests: Functional relations and potential climate feedbacks. Proc Natl Acad Sci U S A (2008) 3.37
The Zta trans-activator protein stabilizes TFIID association with promoter DNA by direct protein-protein interaction. Genes Dev (1991) 3.24
Adenovirus early region 1A protein activates transcription of a nonviral gene introduced into mammalian cells by infection or transfection. Proc Natl Acad Sci U S A (1984) 3.24
Cis-acting induction of adenovirus transcription. Cell (1983) 3.05
Yeast TATA-box transcription factor gene. Proc Natl Acad Sci U S A (1989) 3.03
BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines. Cancer Res (2000) 3.01
The cdk2 kinase is required for the G1-to-S transition in mammalian cells. Oncogene (1993) 2.99
Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection. Virology (1987) 2.85
In vitro transcriptional activation, dimerization, and DNA-binding specificity of the Epstein-Barr virus Zta protein. J Virol (1990) 2.84
Imaging adenoviral-directed reporter gene expression in living animals with positron emission tomography. Proc Natl Acad Sci U S A (1999) 2.71
Adenovirus stimulation of transcription by RNA polymerase III: evidence for an E1A-dependent increase in transcription factor IIIC concentration. EMBO J (1986) 2.62
How proteins recognize the TATA box. J Mol Biol (1996) 2.60
Imaging of adenoviral-directed herpes simplex virus type 1 thymidine kinase reporter gene expression in mice with radiolabeled ganciclovir. J Nucl Med (1998) 2.58
Altered regulation of G1 cyclins in senescent human diploid fibroblasts: accumulation of inactive cyclin E-Cdk2 and cyclin D1-Cdk2 complexes. Proc Natl Acad Sci U S A (1993) 2.55
Adenovirus E1B oncoprotein tethers a transcriptional repression domain to p53. Genes Dev (1994) 2.54
A mechanism for TAFs in transcriptional activation: activation domain enhancement of TFIID-TFIIA--promoter DNA complex formation. Genes Dev (1994) 2.49
The TATA homology and the mRNA 5' untranslated sequence are not required for expression of essential adenovirus E1A functions. Cell (1982) 2.46
Resolution of human transcription factor TFIIIC into two functional components. Proc Natl Acad Sci U S A (1987) 2.43
The p53 activation domain binds the TATA box-binding polypeptide in Holo-TFIID, and a neighboring p53 domain inhibits transcription. Mol Cell Biol (1993) 2.37
NAT, a human complex containing Srb polypeptides that functions as a negative regulator of activated transcription. Mol Cell (1998) 2.33
Phosphorylation of spliceosomal protein SAP 155 coupled with splicing catalysis. Genes Dev (1998) 2.30
Enhanced expression of adenovirus transforming proteins. J Virol (1982) 2.24
Repetitive, non-invasive imaging of the dopamine D2 receptor as a reporter gene in living animals. Gene Ther (1999) 2.21
Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH. Nat Med (1996) 2.19
The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation. Oncogene (2000) 2.15
Ultraviolet mapping of the adenovirus 2 early promoters. Cell (1977) 2.10
Transcription of class III genes activated by viral immediate early proteins. Science (1985) 2.10
Direct cleavage of human TATA-binding protein by poliovirus protease 3C in vivo and in vitro. Mol Cell Biol (1993) 2.09
The effect of regional gene therapy with bone morphogenetic protein-2-producing bone-marrow cells on the repair of segmental femoral defects in rats. J Bone Joint Surg Am (1999) 2.00
An adenovirus early region 1A protein is required for maximal viral DNA replication in growth-arrested human cells. J Virol (1985) 1.97
A cell cycle-regulated inhibitor of cyclin-dependent kinases. Proc Natl Acad Sci U S A (1994) 1.95
Association between proto-oncoprotein Rel and TATA-binding protein mediates transcriptional activation by NF-kappa B. Nature (1993) 1.94
Methods utilizing cell-free protein-synthesizing systems for the identification of recombinant DNA molecules. Methods Enzymol (1983) 1.94
Cyclin E associates with BAF155 and BRG1, components of the mammalian SWI-SNF complex, and alters the ability of BRG1 to induce growth arrest. Mol Cell Biol (1999) 1.91
Sp1 activates transcription without enhancing DNA-binding activity of the TATA box factor. Mol Cell Biol (1989) 1.87
Helminth infestations in immigrant children. Br Med J (1965) 1.87
A class of activation domains interacts directly with TFIIA and stimulates TFIIA-TFIID-promoter complex assembly. Mol Cell Biol (1995) 1.85
Domains required for in vitro association between the cellular p53 and the adenovirus 2 E1B 55K proteins. Virology (1990) 1.85
The 289-amino acid E1A protein of adenovirus binds zinc in a region that is important for trans-activation. Proc Natl Acad Sci U S A (1988) 1.84
Cyclin E, a potential prognostic marker for breast cancer. Cancer Res (1994) 1.82
The zinc finger region of the adenovirus E1A transactivating domain complexes with the TATA box binding protein. Proc Natl Acad Sci U S A (1994) 1.82
Radical mutations reveal TATA-box binding protein surfaces required for activated transcription in vivo. Genes Dev (1996) 1.82
Mechanism of mitochondrial DNA replication in mouse L-cells: asynchronous replication of strands, segregation of circular daughter molecules, aspects of topology and turnover of an initiation sequence. J Mol Biol (1974) 1.80
Factors (TAFs) required for activated transcription interact with TATA box-binding protein conserved core domain. Genes Dev (1993) 1.74
Molecular cloning and characterization of an antigen associated with early stages of melanoma tumor progression. Cancer Res (1988) 1.72
Identification of an overlapping binding domain on Cdc20 for Mad2 and anaphase-promoting complex: model for spindle checkpoint regulation. Mol Cell Biol (2001) 1.70
Early embryonic lethality of H ferritin gene deletion in mice. J Biol Chem (2000) 1.66
A genetically distinct thymidine kinase in mammalian mitochondria. Exclusive labeling of mitochondrial deoxyribonucleic acid. J Biol Chem (1973) 1.64
Cyclin C/CDK8 and cyclin H/CDK7/p36 are biochemically distinct CTD kinases. Oncogene (1999) 1.64
Three RNA polymerase II carboxyl-terminal domain kinases display distinct substrate preferences. J Biol Chem (2001) 1.63
Polyvalent human immunodeficiency virus synthetic immunogen comprised of envelope gp120 T helper cell sites and B cell neutralization epitopes. J Immunol (1989) 1.63
Early events in human T cell ontogeny. Phenotypic characterization and immunohistologic localization of T cell precursors in early human fetal tissues. J Exp Med (1988) 1.62
Cyclin D-CDK subunit arrangement is dependent on the availability of competing INK4 and p21 class inhibitors. Mol Cell Biol (1999) 1.58
Cyclin C/CDK8 is a novel CTD kinase associated with RNA polymerase II. Oncogene (1996) 1.58
Breast carcinomas occurring in young women (< 35 years) are different. Br J Cancer (1996) 1.57
Comparative pathology, and immunohistology associated with clinical illness after Ehrlichia phagocytophila-group infections. Am J Trop Med Hyg (2000) 1.55
Purification and characterization of transcription factor IIIC2. J Biol Chem (1989) 1.54
Functional interaction of adenovirus E1A with holo-TFIID. Genes Dev (1993) 1.54
Arrangement of messenger RNAs and protein coding sequences in the major late transcription unit of adenovirus 2. J Mol Biol (1980) 1.53
Factors responsible for the higher transcriptional activity of extracts of adenovirus-infected cells fractionate with the TATA box transcription factor. Mol Cell Biol (1988) 1.53
Adenovirus 5 early region 1A host range mutants hr3, hr4, and hr5 contain point mutations which generate single amino acid substitutions. J Virol (1985) 1.53
Cyclin E associates with components of the pre-mRNA splicing machinery in mammalian cells. Mol Cell Biol (1998) 1.52
Immunohistologic analysis of the distribution of cell adhesion molecules within the inflammatory synovial microenvironment. Arthritis Rheum (1989) 1.47
Modulation of cyclin gene expression by adenovirus E1A in a cell line with E1A-dependent conditional proliferation. J Virol (1994) 1.46
Intracoronary adenovirus-mediated transfer of immunosuppressive cytokine genes prolongs allograft survival. J Thorac Cardiovasc Surg (1997) 1.46
Mechanism of mitochondrial DNA replication in mouse L-cells: topology of circular daughter molecules and dynamics of catenated oligomer formation. J Mol Biol (1976) 1.46
Prostate cancer susceptibility genes: lessons learned and challenges posed. Endocr Relat Cancer (2003) 1.44
Far upstream initiation sites for adenovirus early region 1A transcription are utilized after the onset of viral DNA replication. J Virol (1983) 1.40
trans-dominant mutants of E1A provide genetic evidence that the zinc finger of the trans-activating domain binds a transcription factor. Mol Cell Biol (1991) 1.39
A Streptococcus mutans superoxide dismutase that is active with either manganese or iron as a cofactor. J Biol Chem (1986) 1.39
Rapid intracellular turnover of adenovirus 5 early region 1A proteins. J Virol (1984) 1.39
Expression of histocompatibility antigens H-2K, -D, and -L is reduced in adenovirus-12-transformed mouse cells and is restored by interferon gamma. Proc Natl Acad Sci U S A (1985) 1.39
Induction of Fanconi anemia cellular phenotype in human 293 cells by overexpression of a mutant FAC allele. J Clin Invest (1996) 1.38
Adenovirus E1B 55K represses p53 activation in vitro. J Virol (1998) 1.37
Transcription control region within the protein-coding portion of adenovirus E1A genes. Mol Cell Biol (1984) 1.36
Functions of adenovirus E1A. Cancer Surv (1986) 1.35