Published in Nat Genet on June 01, 1999
A haplotype map of the human genome. Nature (2005) 105.70
dbSNP: the NCBI database of genetic variation. Nucleic Acids Res (2001) 76.97
The diploid genome sequence of an individual human. PLoS Biol (2007) 44.80
Methods for detecting associations with rare variants for common diseases: application to analysis of sequence data. Am J Hum Genet (2008) 26.79
Are rare variants responsible for susceptibility to complex diseases? Am J Hum Genet (2001) 22.46
Modeling linkage disequilibrium and identifying recombination hotspots using single-nucleotide polymorphism data. Genetics (2003) 17.73
Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology. Genet Med (2015) 16.87
Genetic mapping in human disease. Science (2008) 15.12
Linkage disequilibrium in humans: models and data. Am J Hum Genet (2001) 14.97
Linkage disequilibrium--understanding the evolutionary past and mapping the medical future. Nat Rev Genet (2008) 7.08
The allele frequency spectrum in genome-wide human variation data reveals signals of differential demographic history in three large world populations. Genetics (2004) 7.00
GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers. Neuron (2007) 6.88
dbSNP: a database of single nucleotide polymorphisms. Nucleic Acids Res (2000) 6.84
Ascertainment bias in studies of human genome-wide polymorphism. Genome Res (2005) 6.63
Highly multiplexed molecular inversion probe genotyping: over 10,000 targeted SNPs genotyped in a single tube assay. Genome Res (2005) 6.32
Estimating recombination rates from population genetic data. Genetics (2001) 5.95
Gene conversion and different population histories may explain the contrast between polymorphism and linkage disequilibrium levels. Am J Hum Genet (2001) 5.84
Genetic analysis of case/control data using estimated haplotype frequencies: application to APOE locus variation and Alzheimer's disease. Genome Res (2001) 5.78
A perspective on epistasis: limits of models displaying no main effect. Am J Hum Genet (2002) 5.63
Coalescent-based association mapping and fine mapping of complex trait loci. Genetics (2004) 5.26
Selection and evaluation of tagging SNPs in the neuronal-sodium-channel gene SCN1A: implications for linkage-disequilibrium gene mapping. Am J Hum Genet (2003) 4.58
High-throughput SNP allele-frequency determination in pooled DNA samples by kinetic PCR. Genome Res (2000) 4.55
Statistical tests for admixture mapping with case-control and cases-only data. Am J Hum Genet (2004) 4.52
Distribution of recombination crossovers and the origin of haplotype blocks: the interplay of population history, recombination, and mutation. Am J Hum Genet (2002) 4.29
Linkage disequilibrium and persistence of phase in Holstein-Friesian, Jersey and Angus cattle. Genetics (2008) 4.20
Haplotype diversity across 100 candidate genes for inflammation, lipid metabolism, and blood pressure regulation in two populations. Am J Hum Genet (2004) 3.91
Linkage disequilibrium, gene trees and selfing: an ancestral recombination graph with partial self-fertilization. Genetics (2000) 3.89
Global landscape of recent inferred Darwinian selection for Homo sapiens. Proc Natl Acad Sci U S A (2005) 3.77
Recent developments in genomewide association scans: a workshop summary and review. Am J Hum Genet (2005) 3.76
Sequence features in regions of weak and strong linkage disequilibrium. Genome Res (2005) 3.74
Power of linkage versus association analysis of quantitative traits, by use of variance-components models, for sibship data. Am J Hum Genet (2000) 3.69
Extent and distribution of linkage disequilibrium in three genomic regions. Am J Hum Genet (2000) 3.68
The genetic dissection of complex traits in a founder population. Am J Hum Genet (2001) 3.36
Power to detect risk alleles using genome-wide tag SNP panels. PLoS Genet (2007) 3.29
Whole genome linkage disequilibrium maps in cattle. BMC Genet (2007) 3.28
Microsatellite variation and evolution of human lactase persistence. Hum Genet (2005) 3.20
Comparison of the accuracy of methods of computational haplotype inference using a large empirical dataset. BMC Genet (2004) 3.15
Matching strategies for genetic association studies in structured populations. Am J Hum Genet (2004) 3.13
Fine mapping of a quantitative trait locus for twinning rate using combined linkage and linkage disequilibrium mapping. Genetics (2002) 3.12
Homozygosity and linkage disequilibrium. Genetics (2002) 3.04
When did the human population size start increasing? Genetics (2000) 2.94
Host determinants of HIV-1 control in African Americans. J Infect Dis (2010) 2.90
Haplotype block structure and its applications to association studies: power and study designs. Am J Hum Genet (2002) 2.88
Extensive and breed-specific linkage disequilibrium in Canis familiaris. Genome Res (2004) 2.85
Genetic epidemiology of single-nucleotide polymorphisms. Proc Natl Acad Sci U S A (1999) 2.81
The first linkage disequilibrium (LD) maps: delineation of hot and cold blocks by diplotype analysis. Proc Natl Acad Sci U S A (2002) 2.80
Association testing by DNA pooling: an effective initial screen. Proc Natl Acad Sci U S A (2002) 2.79
Bayesian fine-scale mapping of disease loci, by hidden Markov models. Am J Hum Genet (2000) 2.72
Beyond GWASs: illuminating the dark road from association to function. Am J Hum Genet (2013) 2.67
A second-generation genomewide screen for asthma-susceptibility alleles in a founder population. Am J Hum Genet (2000) 2.62
A global perspective on genetic variation at the ADH genes reveals unusual patterns of linkage disequilibrium and diversity. Am J Hum Genet (2002) 2.60
Assessing the performance of the haplotype block model of linkage disequilibrium. Am J Hum Genet (2003) 2.59
The extent of linkage disequilibrium in rice (Oryza sativa L.). Genetics (2007) 2.56
A coalescent approach to study linkage disequilibrium between single-nucleotide polymorphisms. Am J Hum Genet (2000) 2.53
A SNP resource for human chromosome 22: extracting dense clusters of SNPs from the genomic sequence. Genome Res (2001) 2.49
Multiple sclerosis. J Clin Invest (2004) 2.48
Designing candidate gene and genome-wide case-control association studies. Nat Protoc (2007) 2.42
Population genetic analysis of ascertained SNP data. Hum Genomics (2004) 2.41
The optimal measure of allelic association. Proc Natl Acad Sci U S A (2001) 2.41
Analysis of genomic admixture in Uyghur and its implication in mapping strategy. Am J Hum Genet (2008) 2.30
Mapping in structured populations by resample model averaging. Genetics (2009) 2.30
Linkage disequilibrium in domestic sheep. Genetics (2002) 2.29
Biases and reconciliation in estimates of linkage disequilibrium in the human genome. Am J Hum Genet (2006) 2.26
Linkage disequilibrium and allele-frequency distributions for 114 single-nucleotide polymorphisms in five populations. Am J Hum Genet (2000) 2.25
A validated whole-genome association study of efficient food conversion in cattle. Genetics (2007) 2.23
Unbiased application of the transmission/disequilibrium test to multilocus haplotypes. Am J Hum Genet (2000) 2.22
The genetic architecture of selection at the human dopamine receptor D4 (DRD4) gene locus. Am J Hum Genet (2004) 2.21
Sequence variation and haplotype structure surrounding the flowering time locus FRI in Arabidopsis thaliana. Genetics (2002) 2.10
HaploRec: efficient and accurate large-scale reconstruction of haplotypes. BMC Bioinformatics (2006) 2.08
A linkage map of the Atlantic salmon (Salmo salar) based on EST-derived SNP markers. BMC Genomics (2008) 2.07
Natural variation in Arabidopsis: from molecular genetics to ecological genomics. Plant Physiol (2011) 2.06
A random forest approach to the detection of epistatic interactions in case-control studies. BMC Bioinformatics (2009) 2.03
The extent of linkage disequilibrium in four populations with distinct demographic histories. Am J Hum Genet (2000) 2.03
The portability of tagSNPs across populations: a worldwide survey. Genome Res (2006) 1.99
A novel method for SNP detection using a new duplex-specific nuclease from crab hepatopancreas. Genome Res (2002) 1.98
New explicit expressions for relative frequencies of single-nucleotide polymorphisms with application to statistical inference on population growth. Genetics (2003) 1.97
Pooled DNA genotyping on Affymetrix SNP genotyping arrays. BMC Genomics (2006) 1.96
Variation in the interleukin 4-receptor alpha gene confers susceptibility to asthma and atopy in ethnically diverse populations. Am J Hum Genet (2000) 1.94
Two loci on chromosomes 2 and X for premature coronary heart disease identified in early- and late-settlement populations of Finland. Am J Hum Genet (2000) 1.93
Founding mothers of Jewish communities: geographically separated Jewish groups were independently founded by very few female ancestors. Am J Hum Genet (2002) 1.89
Forward-time simulations of human populations with complex diseases. PLoS Genet (2007) 1.87
MHC haplotype matching for unrelated hematopoietic cell transplantation. PLoS Med (2007) 1.83
Isolated populations and complex disease gene identification. Genome Biol (2008) 1.83
Joint estimates of quantitative trait locus effect and frequency using synthetic recombinant populations of Drosophila melanogaster. Genetics (2007) 1.78
Comprehensive analysis of APOE and selected proximate markers for late-onset Alzheimer's disease: patterns of linkage disequilibrium and disease/marker association. Genomics (2007) 1.78
Data mining applied to linkage disequilibrium mapping. Am J Hum Genet (2000) 1.78
Genetic demography of Antioquia (Colombia) and the Central Valley of Costa Rica. Hum Genet (2003) 1.76
GENOMEPOP: a program to simulate genomes in populations. BMC Bioinformatics (2008) 1.76
A comparison of linkage disequilibrium patterns and estimated population recombination rates across multiple populations. Am J Hum Genet (2005) 1.75
Direct molecular haplotyping of long-range genomic DNA with M1-PCR. Proc Natl Acad Sci U S A (2003) 1.74
Haplotype block partitioning and tag SNP selection using genotype data and their applications to association studies. Genome Res (2004) 1.74
Simulations provide support for the common disease-common variant hypothesis. Genetics (2006) 1.72
Genome screening in human systemic lupus erythematosus: results from a second Minnesota cohort and combined analyses of 187 sib-pair families. Am J Hum Genet (2000) 1.72
Linkage disequilibrium decay and haplotype block structure in the pig. Genetics (2008) 1.71
Genotyping DNA pools on microarrays: tackling the QTL problem of large samples and large numbers of SNPs. BMC Genomics (2005) 1.68
Efficient selection of tagging single-nucleotide polymorphisms in multiple populations. Hum Genet (2006) 1.66
Consistent long-range linkage disequilibrium generated by admixture in a Bantu-Semitic hybrid population. Am J Hum Genet (2000) 1.65
Signatures of founder effects, admixture, and selection in the Ashkenazi Jewish population. Proc Natl Acad Sci U S A (2010) 1.64
The power to detect linkage disequilibrium with quantitative traits in selected samples. Am J Hum Genet (2001) 1.64